Conserved Protein Domain Family
SelD

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cd02195: SelD 
Selenophosphate synthetase (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The N-terminal domain of SelD is related to the ATP-binding domains of hydrogen expression/formation protein HypE, the AIR synthases, and FGAM synthase and is thought to bind ATP.
Statistics
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PSSM-Id: 100031
View PSSM: cd02195
Aligned: 72 rows
Threshold Bit Score: 266.309
Threshold Setting Gi: 33860860
Created: 31-Jul-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ATPdimerization
Feature 1:putative ATP binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
P16456         8 LTQYSHGAGCGCKISPKVLETILhseqakfvdp-nllvgnetrDDAAVYdlg-ngTSVISTTDFFMPIVDNPFDFGRIAA 85  Escherichia col...
ZP_01114202  383 EASTMHCAGCGSKLGPAMLSETLselgy-----------repaEDAVALpl--kqGHLWQSLDGFRSFTDDLYRLGIVSV 449 Reinekea sp. ME...
YP_001550213 360 AESNLLCRGCAAKVSEGTLKEALkevdlq--------klgdypEDASMVssskgtGTLMQSVDGFPALISDPWLNARLTA 431 Prochlorococcus...
NP_874727    353 EEKIIACRGCASKVAAQPLKSALksaeld--------nlinypEDAALVassldkGLWLQSVDGFPALSNDPWLNARLTT 424 Prochlorococcus...
YP_292858    364 EEDMIKCRGCAAKLAFTPLSSALkkvdl----------iesskDDSINIgilnsdKTLIQSVDGFPSLISDPWLNGRLLA 433 Prochlorococcus...
NP_896285    342 ASEPMACRGCAAKLPAQPLAAALeqagl-----------tgapEDAARIeg---dPPLLQSVDGFPALVSDPWLNGRLTT 407 Synechococcus s...
ZP_01471743  309 EKTSMACRGCAAKLPAAPLEQALqrcgig--------elgqqpEDAQAIgatdngATVLSSVDGFPALIPDPWLNGRLTA 380 Synechococcus s...
NP_892421    369 EGGMEECRGCAAKIPQSILNKSLrsaqlen-------fatspeDSVEIYkn--nqDIILQSVDGFPALISDPWLNAKITV 439 Prochlorococcus...
ZP_01084572  363 MVEESPCRGCAAKLGAAPLRGALerlgvaaagvwsadqgspggDDAAVIagsldqGLLLQSLDGFPALVGDDWLNGRLTA 442 Synechococcus s...
YP_693445    382 DPDTLHCAGCGAKVGSDALHEALaelqpvvnp--gieagvdaaDDAAIIdwp-agQRLVQSLDFFPAFIDEPYLFGRIAA 458 Alcanivorax bor...
Feature 1         #   #                                                ###                       
P16456        86 TNAISDIFAMGGKPIMAIAILGWpink--lspeIAREVTEGGRYACRQAGIALAGGHSIDap---------ePIFGLAVT 154 Escherichia col...
ZP_01114202  450 HHAVNDSYAMGLAPSSAQVWINLafshprlarrDFKWLMHGVHDALREHDARLIGGHSTEga---------eTHMAVVVN 520 Reinekea sp. ME...
YP_001550213 432 LHACSDIWASGASVISAQAVITLpvlnsylqkeLLVQSIAGIKSVLEPQGAKLIGGHTFEsrnepieqitlgIEISLSIN 511 Prochlorococcus...
NP_874727    425 LHACSDLWARGASVTSAQAVITLptihqklqqeLLIQCLSGIKSALMPQGAELIGGHTYEsrtelsgnismdIEISLSIN 504 Prochlorococcus...
YP_292858    434 FHSCSDIWACGGSVISAQSLINLpsisnnlqqeLLYQVLEGINSALTIQGANLIGGHTLEsrkiseepfslgIESSLTVN 513 Prochlorococcus...
NP_896285    408 LHACSDLWACGVRVDSAQAIVTLpvleaaeqqeLLVQTLCGVRSVLEEQQAQLIGGHTLEsrsepphcpslgVQLSLCVN 487 Synechococcus s...
ZP_01471743  381 LHACSDLWASGARVTTVHAIVTVpaidpdhqveLLSQTLAGVRSALKEQGADLIGGHTMEsrqpsatpsaldCQLSLSVT 460 Synechococcus s...
NP_892421    440 LHACSDLWACGVKLSSAQALISLpkvgkdfqsfLFSHCLKGIKTTVEEQGGKLIGGHTFEsrslvdqpyslgIDISLTVQ 519 Prochlorococcus...
ZP_01084572  443 LHACSDLWACGARVESVLALVTLprgtaalqeeWLLQTLAGVLSVLDPLGARLVGGHTLEqrtt-----segLSLALSVT 517 Synechococcus s...
YP_693445    459 LHSLSDVYAMNAQPHSALANITLpwhhprlqsrDLQRMMAGAVRELNAAGCTLVGGHTIEgp---------qMAAGFTVN 529 Alcanivorax bor...
Feature 1                                                                                        
P16456       155 GIVPTervkkn-staqaGCKLFLTKPLGIGVLTTAEKKSl------lKPEHQGLATevmCRMNIAGAsfa--------ni 219 Escherichia col...
ZP_01114202  521 AEGQArwpkr---gaqpGDWLMLNRPIGTGILLAADMAGs------aHPADIESLWqhlLTSNRDFFeal--------ad 583 Reinekea sp. ME...
YP_001550213 512 GILKPgqlplnkrglkpKDELLISRGLGSGVIFAGTMHGa------tSSEVLETTLdtlSQSQHFLLedikkpinqnlds 585 Prochlorococcus...
NP_874727    505 GLVVPnirpwskgglqiGDEILISRGIGTGVIFSAAMKGa------vPAKHVDAALfqlSQSQHVFVeglrkqsletnds 578 Prochlorococcus...
YP_292858    514 GVIDDkkyfwpkggmrnGDEILISRSLGTGIIFSAFMNGq------vKPYILDNVLkemNKSQHEIVnyinqltnlnprs 587 Prochlorococcus...
NP_896285    488 GRSAApwskg---giahGDVLLLSRPLGTGVLFAAAMAGa------cQPEALDTVLqhmSRSQHRLLdqle------phr 552 Synechococcus s...
ZP_01471743  461 GETPTgaqpwskgpiqpGDVLLLSRGLGSGVMFAAAMQGr------cDPWHLDACLkqlGTSQHSRLhelfkl--eaedp 532 Synechococcus s...
NP_892421    520 GVLKNgakpwlksgmkkGDIILMSRPLGVGIFFAAQMQNi------nLKDSSEEIMrnlVTSQQPLIdkiyllq-dkfge 592 Prochlorococcus...
ZP_01084572  518 GRSEPgrfwak-gdlaaGDRLLLSRPIGSGVLFAGAMAGa------aEPEWIDGALevmAQSQQPLVell--------aa 582 Synechococcus s...
YP_693445    530 GQADPaqlwhk-hgardGDRLILTKPLGSGVQLAALMQVsrepssafHGPWLDTTLrhlLISNHLAQqal--------qg 600 Alcanivorax bor...
Feature 1                                                                                        
P16456       220 eGVKAMTDVTGFGLLGHLSEMCqg----------agVQARVDYEAIPKLpgveeyiklgavpggternfa---------- 279 Escherichia col...
ZP_01114202  584 tPVNAATDITGFGLIGHVLEMMad----------tsTSAVIEVDTVPLLpgahelskqgvqstllpqlep---------- 643 Reinekea sp. ME...
YP_001550213 586 fVINACTDITGYGLLGHLGEMLkssnhfrelrgesgLRIKLYPDSIPILkgakkllrsgfsstfaqsnrsffsllnsfkn 665 Prochlorococcus...
NP_874727    579 fLIHACTDITGFGLLGHLGEMIqatnikrlkaslplVKINLFANSIPVLdgvknlfklgyestlapsnrcflellnlknk 658 Prochlorococcus...
YP_292858    588 kIVNACTDITGFGLLGHLSEMLestnsdqlkmnsepFKVNLELDKIPLYdgvkelldkgfestlapanqiflknidgd-- 665 Prochlorococcus...
NP_896285    553 qAIHACTDVTGFGLLGHLGEMLass---------spLRITLWTNRIPAYpeamdrlaqgyasslapanrrswq------- 616 Synechococcus s...
ZP_01471743  533 gCIHACTDITGFGLLGHLNEMLaas---------paACVDLWIEKIPSFegaldllksglastlapsnrralaslg---- 599 Synechococcus s...
NP_892421    593 tFINAATDVTGYGFIGHLKEMIdssnllrkdnklkpIRVLLDLFAFKAYpgvfdlihkgiksslfesnkeifdqiiaek- 671 Prochlorococcus...
ZP_01084572  583 hGCRACTDVTGFGLLGHLGEMLeaa--------aepLRVVLEPQALPAFsgalellergfasslapanrsawv------- 647 Synechococcus s...
YP_693445    601 iPVNACTDITGFGLLGHLYEISqq----------sqVSLSVDCHKVPLLpgtlslieqgvastlsdanrqi--------- 661 Alcanivorax bor...
Feature 1                                                                         
P16456       280 ---------syghlmgemprevrdllcdpQTSGGLLLAVMpeaene-vkataaEFGIELTAIGEL 334 Escherichia coli K12
ZP_01114202  644 --------llrdcqierptdarlrclldpQTQGGLLVSVSpehg------qslLDAGLATRIGQV 694 Reinekea sp. MED297
YP_001550213 666 applidldlgdiqhesiehqvikelivdpQTCGPLLVSCPqnvs------qilLNKGPWVRIGLV 724 Prochlorococcus marinus str. M...
NP_874727    659 tvpfielimedissemqevhlikellvdpQTCGPLVISCEskia------nslIDNYYWHRIGFV 717 Prochlorococcus marinus subsp....
YP_292858    666 knlrfeltsndscsnrsfynamlkilvdpQTCGPLVVCCSsiys------eklIQQGPWIKIGFI 724 Prochlorococcus marinus str. N...
NP_896285    617 ------wldgliqlddspsqallellvdpQTCGPLLLACTetta------qtlTAEGPWIPIGNA 669 Synechococcus sp. WH 8102
ZP_01471743  600 --srvrtiqhsedvsnsleagleallvdpQTCGPLLVSCAgat-------ariLGDQGWIAIGQA 655 Synechococcus sp. RS9916
NP_892421    672 rndriiafskknkvnsesfkekisllldpQTCGPLLICCApky--------ekFLKDEWYKVGEV 728 Prochlorococcus marinus subsp....
ZP_01084572  648 ------eletgrvqaaalkaplrellidpQTCGPLLASMPaaaaqaalaavrtAGFPRAELIGTV 706 Synechococcus sp. WH 5701
YP_693445    662 --------lvhcqqqqpvaealltalcdpQTAGGLLFCLHadyakq-alqrldSKGIAAAEIGKV 717 Alcanivorax borkumensis SK2

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