Conserved Protein Domain Family
GT2_SpsF

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cd02518: GT2_SpsF 
SpsF is a glycosyltrnasferase implicated in the synthesis of the spore coat.
Spore coat polysaccharide biosynthesis protein F (spsF) is a glycosyltransferase implicated in the synthesis of the spore coat in a variety of bacteria challenged by stress as starvation. The spsF gene is expressed in the late stage of coat development responsible for a terminal step in coat formation that involves the glycosylation of the coat. SpsF gene mutation resulted in spores that appeared normal. But, the spores tended to aggregate and had abnormal adsorption properties, indicating a surface alteration.
Statistics
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PSSM-Id: 133011
View PSSM: cd02518
Aligned: 44 rows
Threshold Bit Score: 230.151
Threshold Setting Gi: 42527422
Created: 28-Oct-2011
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
ligand binding
Feature 1:ligand binding site
Evidence:
  • Comment:Putative ligand binding site based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1            # #                                                                         
gi 15895459    5 FCIVQARMGSERLQGK---VIKPILKKPMVIYTLDRLKksk----yidKIVLATSsmeretpLVESCEEYGYDVFKGSEA 77
gi 29339024    4 AFVVQARLGSTRLPGK---ILKPFYGNQSILDLMVHKLsai----sniPVIIATTnsvinepIEKKALALGVKCFRGEEN 76
gi 42527422    9 AVIVQARLSSKRLVRK---ALLDLGGMPILYRVLDSVRelp-----aeHFILACDtns-kkeFQPIAESLGYLCIDGSEE 79
gi 19705007    7 AVIIACRLKSSRLKRK---ALLKIGTLSSIEMCIKNVLkfe----dtnSVVLATSiteedsiLKNYTYNKSVIFHQGDPD 79
gi 37999498    4 IGIIQARTGSKRLKNK---VLLKLGDRCILEILLERLKksk----kldDIIVATTikkednaIVELCNSLGVNVFRGSEK 76
gi 24194125   12 YAFIQARTGSSRLPEKvllEFPSGSGKTLVDRIYDRILtvl----pkeQIVYLIPked--keLRYFLNQRNYLFFAGDLL 85
gi 124002188   7 GIIIQARMGSSRLPAKialKLPYSGELSVIEHIIARSKavn----pdyLIAVATSvnaendlLAAMTSQQGVVLFRGDEE 82
gi 730815      5 LFIIQARMGSTRLPGK---VLRPLGSNRLLDILVHRVRqsafyqkdrdNLVIATSdketddiLEAHCIKQGFRVFRGSEE 81
gi 78192930    7 VAVIQARMGSSRLPGK---VLMTVAGKPLLEHIIDRLRrsr----tldDIVIATSdkpcddpLVDFAQTRGVTLVRGSED 79
gi 46581409    4 MAFVQARMGSTRLPGKs--LMPVWNGMGVLEMTLRRALrar----tlsGVVLCTStdpacdaLETLASGLGVQAFRGPED 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                      #                                                 
gi 15895459   78 NVLKRYEqaaeky----ganieDAVIRVTGDCPLIDPiivdnvv-tkflssdYDYVRLdv----pnTFVRGFDVEIFSMK 148
gi 29339024   77 DVLKRFIdvae-------yfdiQGIFRICSDNPFLDVhaarqlv-eiamkscNDYISFdidgtpsiKTHFGFWGEFVTLD 148
gi 42527422   80 DVLRRFCdavefinsnfpnrplKAVIRVTADNPFLFVqaaeasirryfelgePDYFTYt-------GLPHGSGIEIIKAD 152
gi 19705007   80 DVIQRYIdiin-------kknyDVIVRVTGDCPYLSKdickfvl-dshfekgAEYSNGi-------GAAIGTNVEIMNSL 144
gi 37999498   77 DVLDRFYnask-------fysgDVIVRITGDNPLTSIelidkqv-eyllknnFDYVSTk-------NIILGLSSEVFTFD 141
gi 24194125   86 DVRRRYIeaah-------ffnaDSILRLTGDNPFYDTihldqll-qsfqffeSDLSYVs-------GLPLGMGGEIFTRK 150
gi 124002188  83 DVLSRYAaitq-------qyqlDTIVRLTGDNPCIDPvyiekai-eehathkADYTYTq-------GLPLGMNVEVVSNT 147
gi 730815     82 RVLDRFVkvie-------avkpSVIIRLTGDNPFVDPelldvmi-qahfdqgSDYTYIl-------NAPLGICGEVVNAN 146
gi 78192930   80 NVLLRFNkaae-------evdaDVIIRVTGDAPLVDPevmdrlv-rtllqegAEYCTIea-----gINSIHEGFCTFTRG 146
gi 46581409   78 DVLTRYAlate-------rfepDAVVRICADSPLVCPegidalv-affrdegLDYAAHamd---gtGLPDGLGCEVFTAA 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 15895459  149 ALktvnslinggkipkeeadmyKEHVTLYMYKhpneFKVGYVKgdef-----yskdYRLCVDTKEDFelvkniy----eh 219
gi 29339024  149 ALkrvigf--------tddllyREHVTNYIYShpelFNIQWISgspvv---skhhnIRLTIDTLEDFsvaqriyr--dlq 215
gi 42527422  153 SLlkaase--------tddeyaHEHVSPAIYGhsdkYRCVRETappvw----yypeLRTTVDTAEDYekakeiykhlisn 220
gi 19705007  145 CLkeikky--------fpradySEYMTWYFQNnsevFKLNYVDlpnk-----wkrdYRLTLDYQEDLdlfnkvee--yfs 209
gi 37999498  142 ALekawkn--------akekyqREHVTPYIYEnpnlFKVFYLEppeyl----kregIRLTIDTIKDFklylelq----kh 205
gi 24194125  151 ALewtpnt---------leerhKEHVSLHIKEnsdrFRITKLSsllsekeklilpkLRLTIDEPKDFettsnifn--iln 219
gi 124002188 148 ALqiaheq--------gidqneREHVTYFVRQrpdqFVLHYPQvlsde---qdcaqYRLTLDTPSDYalmcllyq--qly 214
gi 730815    147 LLidisriq-------aledqyQEHVTLYIRNhpalYRVQFLEaperf----rapqYRLTIDTKEDYesikalyq---ka 212
gi 78192930  147 ALkrlmtea-------pddpvaIEHVTAYFIAhpdkFHIARIPvgneh----rfkgARLSVDTPADVqffdelyr--llg 213
gi 46581409  147 ALaqahae--------atapedREHVSLFIRHrperFRQATLAadaal----rapgVSLDVDTQDDLdalrrfima-lpp 213
                        250       260
                 ....*....|....*....|....*....
Feature 1                                     
gi 15895459  220 fndefVSSKNVIn--yLDRNSEIAQINND 246
gi 29339024  216 ekrveISIEVIVd--yVRRHAEYIQLMKQ 242
gi 42527422  221 kkavpFTPADIVe--aVSYADRLVVFCPS 247
gi 19705007  210 knninYTIDNLFe--fLDKNPEISKINLN 236
gi 37999498  206 fdlinVDIRQIId--fLDKNPQIKNINSN 232
gi 24194125  220 eqnpiFGARECIn--lFEIDPNVFAGNQN 246
gi 124002188 215 shnhlFGFNEIMe--fFKENPWVKAINQD 241
gi 730815    213 gerpdVSASELIt--lLNRNPDAATETRG 239
gi 78192930  214 vpagdADIADVVr--lLRNNPHLLQINQH 240
gi 46581409  214 segpfWSADAIAplarGLHTPPQGTSMDI 242

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