Conserved Protein Domain Family
Succinoglycan_BP_ExoA

?
cd02525: Succinoglycan_BP_ExoA 
ExoA is involved in the biosynthesis of succinoglycan.
Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.
Statistics
?
PSSM-Id: 133016
View PSSM: cd02525
Aligned: 26 rows
Threshold Bit Score: 228.27
Threshold Setting Gi: 10640362
Created: 10-Mar-2005
Updated: 17-Jan-2013
Structure
?
Aligned Rows:
 
Ligand binding
Feature 1:Ligand binding site
Evidence:
  • Comment:Predicted ligand binding site based on similar proteins.

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1              # #                                                                       
gi 91200950   15 FVTIIMPIRNEASFINRSLGSVLAQdyphnlVEVIIVDGMSDDGTMEIvqsiinnysqtkdnnvpspihspitliDNPSR 94
gi 14521394    2 RISLITTVKNEENSIRAFLESILQQsr--ppDEFIIVDGGSTDKTVEIlqeytplfk---------rkniiykiiVKKGA 70
gi 10640362    5 GASIVVTVKNEGKNLRELLESIEKNdf--tnFETVVVDDLSTDDTEDIvksyr------------------ftvyKRIAC 64
gi 21227241    5 FVSVVVGIRNEERYIEECIESLLRLdypqdsYEIIIVDGMSTDRTRELvqkyp------------------vrllLNERK 66
gi 154248927   5 KVSIVLPVRNEAKTIQKVLDGLLRQey--edIEIIVIDGMSTDETRNIvqryvgrf------------pekvkliENEKV 70
gi 146348646   6 TVSIIIPVYNEELYIEKCLKSIIDQtye-niIEILVIDGMSTDSTRDIlksfen---------------ekialiDNEKK 69
gi 82617370   15 FISIIVAVKNEEKYVRECIDSLLNQsypadkYEIIVVDGLSTDGTWEIlqelkkr-------------npelrlfKNLKE 81
gi 157364739   5 KVSVIIPARNEEKFIEECIRSLMNTsypeekIEILVVDGVSEDGTRSVvekmmek-------------nkcvkliENLKK 71
gi 15900045    9 LVSIVISAYNEEKYLPGLIEDLKNQtypkedIEILFINAMSTDGTTAIiqqfikedt----------efnsirlyNNPKK 78
gi 110800604   2 LVSFIIIAHNEEKNLKNLLEDLNGQtypkklIEVILIDSISSDNTKNVmnefrnsnk----------efnkiiikSNVKK 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                               #                                                        
gi 91200950   95 IVPTGLNSAIRharGDIIIRVDGHAIIDTDYvqqcvk---vlkdtGAECVGGPmvtvgetwlac--vislaqssffgVGG 169
gi 14521394   71 NIAKGRNIAISnssGDIIACTDAGCVLSKAWleeiar--sfeqdpSVDIVSGWyeplatskfe----eivaeitypkLKK 144
gi 10640362   65 SRGEGRNIGVDlsrYGYILFTDGDAKVSEHWisgmv----salaaGNDAVIGNtl---------------------yTGK 119
gi 21227241   67 NVAAARNLGVQnsmGDFVAFTDGDCKADPLWlktlvte-mknapeDVVCVGGPnlifdtdpvfgr-vvghaqetflgSGG 144
gi 154248927  71 YTPSGLNIGIRnssGEYVMIASGHASYSKNYikecvk---aiessECDIAGGVvevlprseskkalaiaeilkhpfgIGG 147
gi 146348646  70 IQSAALNKGIKmskGDIVVRVDAHALYDKNYvrecvntlnkfkedSVVNVGGPtylltsksyven-civflheskfgIGV 148
gi 82617370   82 NAAAGRNIGVRnakGEYVAFIDGDAVADTNWlenisk---tfgnvDAVGVGGPdllppdsayisr-vigmimasplaSGG 157
gi 157364739  72 RKSPGLNIGIKhaaGDVILIADAHSTYPKDYilknvq---nllnsDAHCVGGMinvkprsdtvkakaiayvlshpfgTGG 148
gi 15900045   79 NQASGFNLGVKhsvGDLILKIDAHSKVTETFvmnnv----aiiqqGEFVCGGPrptivegkgkwaetlhlveenmfgSSI 154
gi 110800604  72 ILPCGWNIAISeskGDILLRVDAHSRIPKNFieenv----nciksGEKICGGYreniilnknnwketlllaeksifgSSI 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 91200950  170 VAFRtgrrqg------cyvdtVAFGAYRRnvfnrIGGFDEELvrnQDDEFNFRLTQSGGkirmdpsIRSVYYSRSSLRGL 243
gi 14521394  145 VLRNpskf----------lpsSRSIAFKKkcwkkVGGYPEWLytaEDTLYDILLKRAGCkfvfnpnAVVYWKVRENLRKL 214
gi 10640362  120 RRYMqervkifl-egievtapSVNLAYRKdrfrqLGGFDPKFvtaEDIDLNIRAVKAGFrfatcdsCVVYAKVRENLASF 198
gi 21227241  145 SAQSknslkkh----yvsslpNCNAMYKKntiieAGYFDERFvvgQDGDLNYRINKKGYkflyipeAIVLHHRRGTLKSF 220
gi 154248927 148 ARYKlgavek------tyvdtVAYGVYKRevfekVGLFNENLirnQDIEFNLRLKGSGYrimlipqARAYYFARDKYKEL 221
gi 146348646 149 AKFRqkdyd-------gfvdtVWNGAFYRwifdeIGFYNENFtrsEDNDLNNRILKRGYkiyqnknIIAYYKPRSSIKKI 221
gi 82617370  158 KLNPsvqhimssqagyvkhipTCNLCLRKdvierIGYFDEDFvkgQDLELNTRLVMAGYklyhspmIRVTHYRKQHIRDF 237
gi 157364739 149 AKYRlkiekp------eyvdtVPFGCYRKevfdkLEGFNENLhrnMDIEFNLRMIRNGYkiklfpdIVIDYYARDNYRDL 222
gi 15900045  155 ANYRnssed-------ryvssIFHGMYKRevfqkVGLVNEQLgrtEDNDIHYRIREYGYkiryspsILSYQYIRPTFKKM 227
gi 110800604 148 APYRrnigk-------ryvssIFHGAYSRevfenTGLFNENLartEDNEMNYRIRKNGYkicfnpnIKSYQYTRNNLLKM 220
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
Feature 1                                                     
gi 91200950  244 WKQYFQYGFykvrvi------------qkrgavPSWRHLIPAVFV 276
gi 14521394  215 FRQYYNYAKgdge-----------------anlFFWRYFLVCYFP 242
gi 10640362  199 LRQAYWNGYgryqlemkhpgitrntrvrlghnfFDFLHMVSGAAG 243
gi 21227241  221 SVRMFKYGMwmgelf------------kkhgelVRWYAILPSVAI 253
gi 154248927 222 WKNNFSNGFwvtysk------------kfaenpYRLRHLIPLFFV 254
gi 146348646 222 LSQNYGNGRaigesl------------innrdiVRMRHLVPLIFF 254
gi 82617370  238 TMQIYKWAKakaai--------------ikkhgMTNPSYLSPVFG 268
gi 157364739 223 WNNNFANGYwvmmsn------------lyskrpFSLRHTVPMAFL 255
gi 15900045  228 LHQKYSNGLwiglts------------hvqfkcLSLFHYVPCLFV 260
gi 110800604 221 LEQKFLNGYwigltl------------gvcpkcISIYHLIPFLFV 253

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap