Conserved Protein Domain Family
R3H_sperm-antigen

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cd02636: R3H_sperm-antigen 
R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Statistics
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PSSM-Id: 100065
View PSSM: cd02636
Aligned: 10 rows
Threshold Bit Score: 79.2948
Threshold Setting Gi: 156540079
Created: 28-Mar-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
RxxxH motif
Feature 1:RxxxH motif
Evidence:
  • Comment:The RxxxH motif gives R3H domain its name.
  • Citation:PMID 9787637

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                       #   #                           
CAF04077      47 KKDIEKKVGKFISDsk--eTRLKLPPASKVNRALVHDIAEANgLISHSFGteevdRHLVLFKK 107 Suberites domuncula
AAF53905      47 RKYVDERMGRFAKDd---rRCIEFQPLDKVHRSVIHEVAENGgFIAMSFGredvdRHSVVYKK 106 fruit fly
O75391        49 RKRMEKEVSDFIQDsg--qIKKKFQPMNKIERSILHDVVEVAgLTSFSFGedddcRYVMIFKK 109 human
AAH54697      49 RKKMEKEVSEFIKDst--lQKKKYNPMGKIERSILHDVAEVAgLTSFSFGedeesRYVMLFKK 109 zebrafish
XP_001630538  44 REKVEKDVNKFINDak--rTRLKFPPMNKVQRSIVHDVAEIGgLTTFSFGedevdRYVMLFKK 104 starlet sea anemone
AAI33781      48 RKRMEQEVSQFIQDst--qTRRKFESMGKIERSIVHDVVEVAgLTSFSFGddeetRYVMIFKK 108 African clawed frog
EDS42426      47 RKYAEERLGRLVKDpv--rTYMEFQPLDKVHRSVVHDIAEIAgMVAMSFGvegvdRYIVVYKK 107 southern house mosquito
XP_796847     47 RAKVEKEVDAFLNDsa--rTRLKYPPIDKVYRSIIHDVAEVAgMTSFSFGeaevdRYIMLFKK 107 purple urchin
XP_852612      9 LSSMEKPPSLGDQEsr-heAWEKSQLMNKIERSIQDDTVEVAgLTSFSLReddecHYVMIYHH 70  dog
XP_001599643   7 IRSFKNTCNKFIFKevaiiAVEENASPSVLLFQLLHDVCDVAnILAYSFGedendKHVVIFKK 69  jewel wasp

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