Conserved Protein Domain Family
R3H_unknown_1

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cd02638: R3H_unknown_1 
R3H domain of a group of eukaryotic proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Statistics
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PSSM-Id: 100067
View PSSM: cd02638
Aligned: 5 rows
Threshold Bit Score: 111.392
Threshold Setting Gi: 66557531
Created: 28-Mar-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
RxxxH motif
Feature 1:RxxxH motif
Evidence:
  • Comment:The RxxxH motif gives R3H domain its name.
  • Citation:PMID 9787637

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                      #   #                             
CAB43396      39 VHRIQEELDRFLLQKQLSKVLLFPPLSSRLRYLIHRTAENFd--LLSSFSVGEGWKRRTVICHQ 100 human
XP_417686     14 VGRIAEELEHFMLQGQHHRVLLFPPLSSRLRYLIHRTVENVd--LLSSFSVGEGWRRRTVICHS 75  chicken
XP_001339211 145 VHTVLEELEVFLQRNERKSVLLFPPLPSRFRFLIHETTLNHp--DLSTFSVGEGCARRVVVCYS 206 zebrafish
XP_001606474   9 AEDAEEDLQLFLKSDKRRRVLLFPPVNNYRRFLIHQLVQDNfgdLLQTFSIGQGYARRTVVCYK 72  jewel wasp
XP_624370     34 LSPVSLSVAIITCSFHFYRVLVFPPVNNYRRYIIHQLVRDRf-vDLHTFSIGQGSARRTVVCYK 96  honey bee

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