Conserved Protein Domain Family
R3H_AAA

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cd02645: R3H_AAA 
R3H domain of a group of proteins with unknown function, who also contain a AAA-ATPase (AAA) domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA or ssRNA in a sequence-specific manner.
Statistics
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PSSM-Id: 100074
View PSSM: cd02645
Aligned: 17 rows
Threshold Bit Score: 70.7707
Threshold Setting Gi: 88811456
Created: 28-Mar-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
RxxxH motif
Feature 1:RxxxH motif
Evidence:
  • Comment:The RxxxH motif gives R3H domain its name.
  • Citation:PMID 9787637

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                      #   #                         
gi 51209952  502 RILIETRIAIEKIVNGkkQSVELLSRNVNLRKLQHQLINFYnLRSRSFGeEPNRRLRIFP 561
gi 1723347   505 QALQEAKLAIEIIILNenSIVQLTPRSAYIRKMQHNLIDNYqLRARSFGeEPYRKLRIYP 564
gi 28416489  467 DALEEVRLAIEYIVIPggEPVELLPRRSDIIVRQLELVESYqLAVENLGtHLNPRLQILP 526
gi 57234427  450 LAIHEAEEAIAQVKSSh-IPVELSPQGAYIRRFQHIIAEKEhLSSHSLGkEPHRRVRISR 508
gi 17131401  519 DALEEARLAVEQIVIPkgQPVELLPRSPQVRKMQHELVEHYrLKSHSFGeEPNRRLRIYP 578
gi 168013314 469 DALEEARVAVEQIVIPkvQAVELLPRSPEVLALQVKLVESYqLAWEKTGsGMNKRLRILP 528
gi 159897031 506 EAMEEVEEAISQVMDGstESIELSPQSSYVRRLQHQIVERYnLQSESTGkEPRRRIRIFR 565
gi 71842246  495 SPLEETQFLIDEIIQSkkRAINLLPRSREVRKLQHQLISHYqLKSISVGvEPHRYVRLFP 554
gi 159475499 480 PALEEAQVAVTEIVIPlhQPVELMPRARSVLEAQIKLLERYkLSHEIVGaGAEARIRILP 539
gi 88811456  446 EAAREAEQAAQRVLAQg-IAVELTPRSAPIRRMQHRIAMRHrLLAESAGsDPQRRLVLHP 504

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