Conserved Protein Domain Family
PurM-like2

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cd02691: PurM-like2 
AIR synthase (PurM) related protein, archaeal subgroup 2 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.
Statistics
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PSSM-Id: 100036
View PSSM: cd02691
Aligned: 9 rows
Threshold Bit Score: 439.902
Threshold Setting Gi: 156937218
Created: 6-Jun-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ATPdimerization
Feature 1:putative ATP binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2622644    84 MGEMGVGSRGEGDFFVHRKIadivsstgtrsfinpeaqddggvvrtetgsgdVYITTAVDGIHSRLSeYPFLGGFHVTRA 163
gi 156937218  69 AGEGGVGSRGLGDWAVHEALtslsgg--------------------gdaarvGDLVLAVDGFHSRLSsVPLLMGFHAVRA 128
gi 1707818    72 AGEAGLGSRGIGDNLIHTKLfelagkqie---------------eyddagirENVVVSIDGIHSRLSyFPFLAGFYATRA 136
gi 146304896  66 AGDSGLGSRGLGDNLIHLKLfelskrnle---------------tfddagivQDIVVSVDGIHSRLSyFPFLAGFHATKA 130
gi 20094929   77 MGEMGVGSRGEGDFFVHELLtrlaakasegalvsp--eerddagavridpdeVILVSAVDGMHSRLSeFPFLAGFHATRA 154
gi 11499940   69 MGEFGVGSRGRGDFYVHEKIaevigdsgavvss------kdlddagvvkfgdFYISVAIDGIHSRLSeFPFIAGFHVTRA 142
gi 20089792   81 MGEFGVGSRGTGDFYVHSKLgevigqtgavvds------aqlddsgvvkignEYLVVTIDGIHSRLSdFPFLSGFHVARA 154
gi 37999514   79 MGRMGVGSRGEGDFFVHREIarivkstkvkayvs----aeeqddagivradaKYIVAAIDGTHSRLSdFPFLGGFHVTRA 154
gi 84490291   74 MGEFGVGSRGQGDFYVHNQIaqiikntdtssivnp---taqddggvvkvedtYYITTAIDGIHSRLSdYPFLAGFHTARA 150
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1           #                                             ###                            
gi 2622644   164 ALRDVCVMGSRPVALISDLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMVLGDRLVSAVGAIGFSEtpp 243
gi 156937218 129 AVRDVMVSGGAPVASLIDVHVADDTDVAYLLDVTAGAYVAGELTGAPLVGGSTLRIGGDAVIGNRVTGGAFAVGRKVrdw 208
gi 1707818   137 TLRDIMVKGAYPLGLIVDIHLSDDSDIGMLIDFEAGVTTISKALDIPILAGSTLRIGGDLVLGDRISGAVGSIGILKskd 216
gi 146304896 131 TLRDIMVKGAIPLGILVDIHLSDDSDVSMLFDFEAGVSTVADALNVPILAGSTLRIGGDMVLGERISGGVASVGRLQgep 210
gi 20094929  155 AMRDVLVNGARPRGLLVDLHLADDGDVGRLFDFTAGVTAVGAATGVPILAGSTLRVGGDMVLGRRLVAGVACVGTARpde 234
gi 11499940  143 AMRDVYVMGAEPVAVFSDIHIADDGDVSKIFDHIAGITAVCEAVKVPLVSGSTLRIGGDMVIGERMTGGVGCVGVSKhit 222
gi 20089792  155 ALRDVYSMGSRPLAMLSDIHVADDGDVAKIFDHIAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGITSslt 234
gi 37999514  155 ALRDIYVMGAEAVALISDVHLADDGDVGKIFDFTAGICAVSEAVNVPLIGGSTLRVGGDMVIGDRLVSAVGAIGVIKege 234
gi 84490291  151 TLRDVCVMGANPVALISDIHLADDGDVGKILDYTAGICAVSELTQVPLVSGSTLRIGGDMVLGDRLVGAVGAVGSSNtlp 230
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2622644   244 tar-kraepgDVILLTEGSGGGTITTTAIYHGLFDVVWETLDVNFIraSEAIMdsgLLGDVHAMTDVTNGGLRGDAHEIS 322
gi 156937218 209 srf--naspgDELYATVGKGGGTVTAYALTHGRPELVKLTLNVDFV--YDIKRa-mEVECVKGAFDWTNGGIALDAFEIS 283
gi 1707818   217 flr-krvkkgLKILMTEGNGGGTIATTAIYNGMPDVISETLNIKDLltCIIVRd-yLSSDVYSMTDVTNGGIRADALEVS 294
gi 146304896 211 ftr-krisegQHIVMTEGHGGGTISSMAIFHGIEGVVEETLRVKDLeaCLAVRr--VRNLVSSMTDVTNGGIRGDALEIS 287
gi 20094929  235 ltprrdaepgDLIVLTEGAGGGTISTTAIYHGYYDVVEETLNVDFVraVEALReenLLSEVHAMTDITNGGIRGDATEIS 314
gi 11499940  223 prr--nvrdgDVILLTEGAGGGTVATTAIYFGMHEIVEETINLDFIkaVRAIFkadLVRRIHSMSDVTNGGIRGDAEEIA 300
gi 20089792  235 srn--rtrpgDLILMTEGAGGGTVSTTALYYGMHDVVEETINIRFLeaCEALLqsgLYKKVHSMTDVTNGGIRGDAREIS 312
gi 37999514  235 ptarrnaevgDVILMTEGSGGGTITTTALYYGWFDVIYETLNVDFIkaCQNLIrsgLIKKIHAMTDVTNGGLRGDAYEIS 314
gi 84490291  231 kar-snakegDLILMTEGCGGGTITTTSIYNNYPEVIKETLNVQFIkaSQLLNnypSEDKIHAMTDITNGGIIGDSNEIN 309
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2622644   323 STAGVGLEFDADAVmsmiNPSVLRMLQDLEIDPLGVSIDSLMIIApedvapdvmdtirgagvdVAEIGRVTDSGVpvl-l 401
gi 156937218 284 RKLGVKVVLWKSVYea-vHPELLKAFEEDGIDPLRTSVDSVVFVAergc-----------elpFVKVGEVEAGEGv---- 347
gi 1707818   295 KITNLSFVIDEEKFlsliNPKVRKMLNEINIDPFGISIDSILIFTdnpdlvkk--rlaqynirSEIVGYIDDFRQypi-- 370
gi 146304896 288 EVTNVSLVIDEDEFlsliNPRIRKAMNELGIDPFGLSLDSILIFTnnpdevir--tlrdnhvqAKTIGEVTRRRGypi-- 363
gi 20094929  315 ETAGVRLVFDEETVrslvNDRVLRMLDELDIDYLGLSLDMLMVIApedvaercvealngvgvrADVVGRVEEGSGvvl-e 393
gi 11499940  301 KVSGLALIFDYDKVrncvNPKVLKMLEELEIDFMGVSIDSLMVVCdaetaelvksavkeagvrIEEVGWVEKGRKgafvv 380
gi 20089792  313 KTAKVKMVFEEEKMrtlvNPKVLSMLEALKIDYLGVSLDALLVIAppeyageilktvraagveIDIIGRVEEGIGaei-i 391
gi 37999514  315 KTAKVSLIFDKEKVyktiNPKVLEMLEVLNIDPLGVSTDSLMIICpeeyadd-----ikkvtgAIEVGYVEEGEEsyl-v 388
gi 84490291  310 KTTGLGIHLYSENIknliNSKVYNMLDDLDIDVLGVSVDSLMIIVseeesdtiirllnenkikTDVIGKITNTGKtyled 389
                        330       340       350
                 ....*....|....*....|....*....|....
Feature 1                                          
gi 2622644   402 rdGSEEELRPLFREAAYTQIKKMVGDKTPQDFEE 435
gi 156937218 348 -yLEGEELEPAFREAPYTHSKRAVEGLERGADPE 380
gi 1707818   371 itYDGKELKPQFRESPYTPIKKYFGNYSPYSIEY 404
gi 146304896 364 vtRDGREMRPAFRESPYTPIKAVIGNYSPMDLDE 397
gi 20094929  394 rdGEEVELDVKFRETAYTKVKRVIGEEHPEEFEE 427
gi 11499940  381 egGEIREIKPRFRESAYTPLKKVVGEETPPDFEE 414
gi 20089792  392 vnGETRDFAPRFRESAYTPVKKIHGEDNPRDFEE 425
gi 37999514  389 dgNKKIPLKPMFRESAYTPVKKVVGERKPGDFEE 422
gi 84490291  390 esGNIKQLVPKFREAAYTPIKKVIDSINEVDFEE 423

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