Conserved Protein Domain Family
GT1_Glycogen_synthase_GSY2_like

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cd03793: GT1_Glycogen_synthase_GSY2_like 
Glycogen synthase, which is most closely related to the GT1 family of glycosyltransferases, catalyzes the transfer of a glucose molecule from UDP-glucose to a terminal branch of a glycogen molecule, a rate-limit step of glycogen biosynthesis. GSY2, the member of this family in S. cerevisiae, has been shown to possess glycogen synthase activity.
Statistics
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PSSM-Id: 99967
View PSSM: cd03793
Aligned: 13 rows
Threshold Bit Score: 1036.91
Threshold Setting Gi: 110637984
Created: 5-Dec-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619      7 NHLLFETATEVANRVGGIYSVLKSKAPItvaQYKDHYHLIGPLNkatyqnevdildwkkpeafsdemrpvqhALQTMESR 86
gi 45446490   48 NRWNFEVAWEVANKVGGIYTVIRSKAYVsteEMGEQLCMMGPYKehcartemeem-------efprgnplldAVNSLRSR 120
gi 6425330    43 GRFVFECAWEVANKVGGIYTVLRSKAQIsteELGDQYCMFGPMKdgkwrlevdp--------iepenrtiraAMKRFQAD 114
gi 57229362    7 NPFLFEAAWEVANKVGGIYTVIKTKVPVtvrEYGDRLCLIGPLSyksapvevea--------eepgpgpfgdALRSMQER 78
gi 66827711   48 HTVLFDLSWEVAKKVGGIYTVLKTKAPVtveEYKSRYALIGPYNastaptefep--------lipgplsspiIENMMKKY 119
gi 28949926   13 NHLLFEVATEVAHRVGGIYSVLKSKAPVttaEYGDRYTLIGPLNhqsaavevee--------lepsnpelkaTIQAMRDR 84
gi 183355     26 NAVLFEVAWEVANKVGGIYTVLQTKAKVtgdEWGDNYFLVGPYTeqgvrtqvel--------leaptpalkrTLDSMNSK 97
gi 41056213   26 DAVLFEIAWEVANKVGGIYTVIQTKARLtceEWGENYFLVGPYMesnvrtqvel--------iepcnaalrrTIDKMNSS 97
gi 118083110  27 DLLLFEVSWEVTNKVGGIYTVIQTKAKItadEWGENYFLIGPYFehnvktqvev--------ceppnpaikkAMDTMKSQ 98
gi 147901679  27 DLLLFEVAWEVTNKVGGIYTVIQTKAKVtadEWGDNYFLMGPYMehnvrtqvei--------cdppnghirkAIDVLQSQ 98
gi 56718386   33 NKWVFEIAWEVANKVGGIYTVIKSKAPVsvaELGEQYCLLGPYNeacvrtevei--------lepshyvyrqTLQTMRDA 104
gi 156390449  16 PYFTFEVSWEVANKVGGIYTVIRSKAATsvdIHGDNYCMMGIYNkaqcnmevem--------tepdmkamkgALKCMRNK 87
gi 110637984   7 DCLLTEVAWEVCNQVGGIYTVIRSKVPTmteVWGDRYCLVGPYFhnkaiaefeai------dtyeaddvfaqAVLRMRNL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619     87 GVhfVYGRWLIEGAPKVILFdldsvrgYSNEWKGDLWSlVGIPSPENDFetndaiLLGYTVAWFLGEVAhl--------- 157
gi 45446490  121 GYkiHTGRWLVDGNPQLILFdigsaawKLDQFKSEMWEkCHIGIPHLDIetndaiILGFMIAEFLEEFRnfavtysqnne 200
gi 6425330   115 GFrcMYGRWLIEGYPKVILFdlgsgavKMNEWKHELFEqCKIGIPHEDIesndavILGFMVALFLKHFResv-------t 187
gi 57229362   79 GVklLYGRWLIEGAPRVLLFdtgscydRMDEWKGDLWNlAGIPSPPNDHetnetiVFGYMVAWFLGEFAar--------- 149
gi 66827711  120 GIhvHFGKWLVEGYPKVFLIdl---hsSMHKLGEWRWDlMSGFEQAGDNetnetiVFGYQSALLLKEFAea--------- 187
gi 28949926   85 GIgiLYGRWLIEGAPRVLLFdtktaygYMNEWKTDLWNvASIPSPDNDEetneaiVFGYLVAWFLGEFVch--------- 155
gi 183355     98 GCkvYFGRWLIEGGPLVVLLdvgasawALERWKGELWDiCNIGVPWYDReandavLFGFLTTWFLGEFLaq--------s 169
gi 41056213   98 GCkvYFGRWLIEGSPYVVLLdvgftawSLDRWKSELWEkCNIGVPWFDReandavLFGFLTAWLLGEYAaq--------c 169
gi 118083110  99 GCqvFFGRWLIEGSPYVLLFdigsaawNLDRWKGEFWDaTNIGIPFHDReandavIFGSLTAWFLKELScq--------f 170
gi 147901679  99 GCqvYFGRWLIEGNPYVVLFdigsaawNLDRWKGEFWDcCTVGIPYNDReandalIFGSLTAWFLKELTdq--------f 170
gi 56718386  105 GIkvHFGRWLIDGYPKVILFdigsaawKLDEFKHELWEkASIGIPWHDResndavIFGALVAWFIGEFRkn--------l 176
gi 156390449  88 GVqvHFGRWLIEGYPKVVLFdigsvyhKLNKWKADLWEnCHIGLPDGDTeandslVLGCLVAQFISEFRsr--------f 159
gi 110637984  81 GYevHYGHWLVSGRPKVVLInhfsafyRLGEIKYSLWEnHGISSPEGDDllnqviAFGFLAKVFHQQLDet--------- 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619    158 dSQHAIVAHFHEWlAGVALPLCRKRRIdvVTIFTTHATLLGRYLCAsgsFDFYNCLESVDVDheaGRFGIYHRYCIERAA 237
gi 45446490  201 lSAPRIVAHFHEWqAGVGLIVLRTRLVeiATVFTTHATLLGRYLCAg-nTDFYNNLDKFAVDeeaGKRQIYHRYCLERGA 279
gi 6425330   188 sYTPLVVAHFHEWqAGVGLLMTRLWKLdiATVYTTHATLLGRHLCAg-gADLYNNLDSFDLDaeaGKRKIYHQYCLERAA 266
gi 57229362  150 eTDNAIVAHFHEWqAGLAIPLCRKRHIdvTTIFTTHATLLGRYLCAg-sVDFYNNLQYFDVDheaGKRGIYHRYCIERSS 228
gi 66827711  188 nPNDKYIAHFHEWqASVGLILLKKWKVpvSTIFTTHATLLGRYLAAg-gVDLYNQMQVLNMDfeaSKRGIYHRHWIEKKS 266
gi 28949926  156 eKRKAVIAHFHEWlAGVALPLTKKRQIdvTTIFTTHATLLGRYLCAg-sVDFYNNLQWFDVDaeaGKRGIYHRYCIERAA 234
gi 183355    170 eEKPHVVAHFHEWlAGVGLCLCRARRLpvATIFTTHATLLGRYLCAg-aVDFYNNLENFNVDkeaGERQIYHRYCMERAA 248
gi 41056213  170 dEPPHIVAHFHEWlAGLGLVLCRQRQLpvSTIFTTHATLLGRYLCAg-nVDFYNNLAEFNVDkeaGDRQIYHRYCLERAA 248
gi 118083110 171 dDKPNVVAHFHEWqAGVGLILSRSQKLpvATIFTTHATLLGRYLCAa-nIDFYNNLDQFDIDkeaGERQIYHRYCMERAS 249
gi 147901679 171 qDKPGVIAHFHEWqAGAGLVLCRNQKLpvATIFTTHATLLGRYLCAa-nVDFYNQLDQFDIDreaGDREIYHRYCMERAA 249
gi 56718386  177 tDQPIVVTHFHEWlAGAGLMDLRTRKVdcITIFTTHATLLGRYLCAg-sSDFYNNIDKYNLVkeaGDRQIYHCYCMERTA 255
gi 156390449 160 dPEIPVVAHFHEWqAGVGEIMLRTKKVnvSTVFTTHATLLGRYLCAa-nVDFYNNLERFDVDkeaGDRGIYHRYCLERAA 238
gi 110637984 152 kGELPCVSHFHEWmTGTAIPEMRREHVktSIVFTTHATLLGRYLAMn-dPNFYDNLPYYDWNkeaVNFNIEPAVKIERAA 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619    238 AHsaDVFTTVSQITAFEAe-HLLKRKPDGILPNGLNVIKFQaFHEFQNLHALKkeKINDFVRGHFHGc-fDFDLDNTLYF 315
gi 45446490  280 THlaHVFTTVSEITGYEAe-HLLKRKPDIITPNGLNVKKFSaIHEFQNLHAVAkeKINEFVRGHFYGh-iDFDLDKTLYF 357
gi 6425330   267 CQtaHIFTTVSEITGLEAe-HFLCRKPDVLTPNGLNVVKFAaLHEFQNLHAQNkeKINQFIRGHFHGh-lDFDLDKTLYF 344
gi 57229362  229 AHcaDVFTTVSHITAFESe-HLLKRKPDGVLPNGLNVVKFAaMHEFQNLHVQSkeKINEFIRGHFYGh-yDFDLDNTIYM 306
gi 66827711  267 AAdsHVFTTVSEITGYESe-HILMRKPDVILPNGLKLDKFTaLHEFQNLHAKYkgVLNEFVRGHFYGhysDFDLDNTLYV 345
gi 28949926  235 AHscDVFTTVSHITAYESe-HLLKRKPDGVLPNGLNVTKFSaMHEFQNLHQQNkeKIHDFVRGHFYGh-yDFEPENTLYF 312
gi 183355    249 AHcaHVFTTVSQITAIEAq-HLLKRKPDIVTPNGLNVKKFSaMHEFQNLHAQSkaRIQEFVRGHFYGh-lDFNLDKTLYF 326
gi 41056213  249 CRcaHVFTTVSQITAIEAe-HLLKRKPDIVTPNGLNVKKFSaMHEFQNLHAQSkaRIQEFVRGHFYGh-lDFNLDKTVFL 326
gi 118083110 250 VHcaHVFTTVSQITAIEAe-HMLKRNPDVVTPNGLNIKKFSaMHEFQNLHSMYkaRIQEFIRGHFYGh-lDFSLENTLFF 327
gi 147901679 250 VHcaHVFTTVSQITGIEAe-HMLKRKPDVITPNGLNIKKFSaTHEFQNLHAMYkaQIQEFVRGHFYGh-lDFSLEKTLFF 327
gi 56718386  256 VHssQVFISVSEITEVEAehLLKRKPNMIVPPNGLNVVKFStIHEFQNMHAICkeKIHDIVRGHFYGh-yDFDLDKTLYF 334
gi 156390449 239 AHaaHVFTTVSRITADEAe-HLLKRKPDLVVPNGLNVVKYTaLHEFQNLHAKSkeKINDFVRGHFYGh-fDFDLDKTLYF 316
gi 110637984 231 AHgaNVFTTVSEVTARECq-SLLGRNPDMVLPNGLNIERFTaLHEFQNLHKEHkdQIHEFVIGHFFQs-yTFDLDKTLYF 308
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619    316 FIAGRYEYKNKGADMFIEALARLNy----rLKVSGSKKTVVa-FIVMPAKNNSFTVEALKGQAEVRALENTvhevtTSIG 390
gi 45446490  358 FIAGRYEFGNKGADIFIEALARLNa----mLKHEKPDTTVVa-FLIFPTKTNNFNVDSLRGHAVIKQLRDTinnvqQAVG 432
gi 6425330   345 FTAGRYEFSNKGGDMFIESLARLNhylkttSDPRHMGVTVVa-FLIYPAPANSFNVESLKGQAVTKQLKEAvdrikEKVG 423
gi 57229362  307 FTAGRYEFRNKGVDMFIESLARLNh-----RLKKMGSKTTVvaFIIMPAATNSYTIEALKGQAVTSQLKDCveqvtNRIS 381
gi 66827711  346 FTAGRHEYFNKGVDMFLDSLAGLNk----lLQQSGSKMTVVa-FIIMPAATNNFNVESLKGHSYLKDMRRTcntivEAMG 420
gi 28949926  313 FTAGRYEFRNKGVDMFIESLARLNh----rLKTAGSKTTVVa-FIIMPAQTTSLTVEALKGQAVIKSLRDTvdvieRGIG 387
gi 183355    327 FIAGRYEFSNKGADVFLEALARLNy----lLRVNGSEQTVVa-FFIMPARTNNFNVETLKGQAVRKQLWDTantvkEKFG 401
gi 41056213  327 FIAGRYEFSNKGADIFLEALARLNy----lLRVNHSEVTVIa-FFIMPARTNNFNVETLKGQAVRKQLWDTaqsvkERFG 401
gi 118083110 328 FIAGRYEFSNKGADMFLEALSRLNf----lLRVHKSDVTVVv-FFIMPAKTNNFNVETLKGQAVRKQLWDTaqsvkEKFG 402
gi 147901679 328 FIAGRYEYTNKGADIFLEALSRLNf----lLRVHRSDVTVVv-FFIMPTKTNNFNVETLKGQAVRKQLWDTahsvkEKFG 402
gi 56718386  335 FTAGRYEFSNKGADMFIESLARLNf----yLKQANSEATVVa-FLIFPTKTNNFNVESLRGQAISKQLKETvhhvqTQIG 409
gi 156390449 317 FAAGRYEYFNKGADVFLESLARLNy----qLKTNNSETTVVa-FLIFPTKTNNFNVDSLRGQAVTKQLKETvneiqDKIG 391
gi 110637984 309 FTSGRYEYKNKGFDITLEALARLNw----rLKEENTDTTVVm-FFITKQPYHTINPQVLQSRAVMEEVRSNcdaivQQLG 383
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619    391 KRIFDHAIRYPhnglttelptdlgellkSSDKVMLKRRILALRRPEgqlPPIVTHNMVDDANDLILnkirQVQLFNSPSD 470
gi 45446490  433 KRMFDTCLQGNipnad--------dllqKDDLVKIKRCMFAMQRDSm--PPVTTHNVADDWNDPVLssirRCHLFNSRHD 502
gi 6425330   424 QRIFDICLQGHlpepe--------elmsPADNILLKRCIMSLHNSS---LPPICTHNMIRADDPVLeslrRTSLFNKPED 492
gi 57229362  382 KRIFEHACRYSgehgtevp--npedllsNEDRVLLKRRVFALKRNSl--PPIVTHNMADDANDPILnqlrRVQLFNRPED 457
gi 66827711  421 ERLFEATSRGKmispe--------ellsQEDLVMLKRRIFALKQKSs--GPPVVTHNMINDNDEILqhirRIKLFNSQED 490
gi 28949926  388 RRIFERSVKWHegdplpe----ekelitSQDRVLLRRRLFAMKRHTl--PPIVTHNMLNDHEDPILnqirRVQLFNHPSD 461
gi 183355    402 RKLYESLLVGSlpdmn--------kmldKEDFTMMKRAIFATQRQSf--PPVCTHNMLDDSSDPILttirRIGLFNSSAD 471
gi 41056213  402 KKLYESLLVGQlpdvs--------kmldKEDFTMMKRAIFATQRQCq--PPVCTHNMLEDSSDPILncirRIGLFNSAQD 471
gi 118083110 403 KKLYNALLKGEipdls--------kildRDDITIMKRAIFSTQRHCl--PPVTTHNMIDDGNDPILntirRIGLFNNRTD 472
gi 147901679 403 KKLYEALLKGEipdln--------kildRDDVTIMKRAIFATQRQSl--PPITTHNMVDDSTDPILntvrRIGLFNSRTD 472
gi 56718386  410 KRIFEQSLKGKiltgd--------eileQEDIVKLKRCIYSAQRNSl--PPICTHNVNEDANDQILnalrRCQLFNRKED 479
gi 156390449 392 KRIYESCVKGNlpsge--------sllePDDIVRLKRCVLGAQHPEm--PPVVTHNVLNDATDPILchirRIQLFNTRHD 461
gi 110637984 384 DKLFEAAASSGdlklpd-----lnkfvdEYWKLRLRRTLLSWKSHEl--PKVVTHNLVYDNQDEILnflrHSNMVNNEHD 456
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171619    471 RVKMIFHPEFLNanNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVmGVPSITTNVSGFGSYMEDLIetnqaKDYG 550
gi 45446490  503 RVKMVFHPEFLTstNPLFGIDYEEFVRGCHLGVFPSYYEPWGYTPAECTVmGIPSVTTNLSGFGCFMEEHIsd--pKSYG 580
gi 6425330   493 RVKVVFHPEFLSsvSPLIGLDYEDFVRGCHLGVFPSYYEPWGYTPAECTVmGIPSVSTNLSGFGCFMQEHVed--hEQKG 570
gi 57229362  458 RVKVIFHPEFLNsnNPILGLDYEEFVRGCHLGVFPSYYEPFGYTPAECTVmGIPNITTNLSGFGCFMEDLLes--pEDYG 535
gi 66827711  491 RVKVIYHPEFLTstNPLIPLDYTEFVRGCHLGIFPSYYEPFGMTPAECCAsGCPSITSNLTGFANYMSRALqd--tDSKG 568
gi 28949926  462 RVKIVFHPEFLSsaNPVLPLDYDDFVRGTHLGVFASYYEPWGYTPAECTVmGVPSITTNLSGFGCYMEELIen--sSDYG 539
gi 183355    472 RVKVIFHPEFLSstSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVmGIPSISTNLSGFGCFMEEHIad--pSAYG 549
gi 41056213  472 RVKVIFHPEFLSstSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVmGIPSISTNLSGFGCFMEEHIad--pSAYG 549
gi 118083110 473 RVKVIVHPEFLSstSPLLPLDYEEFVRGCHLGVFPSYYEPWGYTPAECTVmGIPSVTTNLSGFGCFMQEHVad--pAAYG 550
gi 147901679 473 RVKIIVHPEFLSstSPLLPLDYEEFVRGCHLGVFPSYYEPWGYTPAECTVmGIPSVTTNLSGFGCFMQEHVad--pTAYG 550
gi 56718386  480 RVKVVFHPEFLNstNPLFGLDYEDFVRGCHLGVFASYYEPWGYSPAECTVyGIPSISTNLSGFGCFMQEHInd--pKSYG 557
gi 156390449 462 RVKIVFHPEFLSniNPLLAMEYSEFVRGCHLGVFPSYYEPWGYTRAECTVmGIPSVTTNLSGFGRFMAEHVcd--pTSYG 539
gi 110637984 457 KVKVVYHPDFIAstNPLFGMEYGQFVRGCHLGVFPSYYEPWGYTPLECMAsGVPAITSDLSGFGDYVLKNIpn--nENKG 534
                        570       580       590       600       610       620
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 171619    551 IYIVDRRFKApDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKRMGlEYVKARQLALRR 616
gi 45446490  581 IYIVDRRYIGlENSVQQLSSFMMEFSRLNRRQRIIQRNRTERLSDLLDWRTLGiYYRQARVKALQA 646
gi 6425330   571 IYVIDRRHKAaEESVQELAQVMYDFCGQSRRQRIILRNSNEGLSALLDWQNLGvFYRDCRRLALER 636
gi 57229362  536 CYIVDRRGQGiEESVDQLTGQLLSFTTKSRRQRINQRNRTERLSELLDWKSLGlEYAKARQLALRR 601
gi 66827711  569 IFIVDRRFKSsRETVDQMTQYLWKFTQLDRRQRIELRNATEKLSELLDWRTLGkFYKTARALALER 634
gi 28949926  540 IYIVDRRSKGvDDSVNQLTQYMFEFTQKSRRQRINQRNRTERLSDLLDWKRMGmEYVKARQLALRR 605
gi 183355    550 IYILDRRFRSlDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKYLGrYYMSARHMALSK 615
gi 41056213  550 IYILDRRYRSvDESCNQLTSFLFQFCQQSRRQRIIQRNRTERLSDLLDWRYLGrYYVSARHLALAK 615
gi 118083110 551 IYIVDRRFRSpDESCNQLTQFLYGFCQQSRRQRIIQRNRTERLSDLLDWRYLGrYYMHARHLALSR 616
gi 147901679 551 VYITDRRFRSpDESCNQLTQLLYGFCQQSRRQRIIQRNRTERLSDLLDWRYLGrFYKHARHLALCR 616
gi 56718386  558 LYIVDRRYKSpDESIHQLTQYMYDFTCLSRRQRIIQRNRTERLSDLLDWRNLGvYYRKARQIAVAR 623
gi 156390449 540 IYIVDRRFKCaEESIQELSGYMFSFCTMTRRQRIIQRNRTERLSELLDWKSLYrFYARARLLGLHR 605
gi 110637984 535 IYVTNRFHKSyHDAAQQLADQMYHFVHLSRRDRITQRNRVESASEHFDWQNLGsYYDKAHRLAFSI 600
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