Conserved Protein Domain Family
GT1_mtfB_like

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cd03809: GT1_mtfB_like 
This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Statistics
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PSSM-Id: 99981
View PSSM: cd03809
Aligned: 358 rows
Threshold Bit Score: 164.855
Threshold Setting Gi: 78183706
Created: 6-Dec-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815    2 HIILATESIrh--plTGVGRYTQELAAHLaa--------lPQIESLQYLHGRRllqqrpspgpasaaasw-----mrdrf 66
gi 13932334   73 KIVVSFTDDgrrgvaGAISRAISIVMRGIs---------lRASVIAGLSEKLGffspvefedfvwrrffaktlpvddrph 143
gi 159028564   9 KVLIVGNYVnd--rqISINRFVGLVEKGLrqk------ghEIRRVQAQPIFGQlkpsprgigkwlg-------------- 66
gi 62423868   15 RVFFDARFTrtt-hhDGISRYGSCLLEALlna------vaGTDIEVTAIISDEdqlallpk------------------- 68
gi 148927306  51 KIFFDARWTrtd-rhDGVSRYSANLLGALa---------rIHPVTAIIHNKDQlkllpeg-------------------- 100
gi 149279791   9 KILLDAHIFdh--sfQGTATYIYGLYTALvafe----rleITLCAHDVDNLKQlfpdpr--------------------- 61
gi 134097289   2 NVFIDARWTrtd-thDGISRYGANLIEALhqlhp--vtmlIHDVRQLDLLPDGvphv----------------------- 55
gi 108761847  15 ALLMDPREEg----wPSMDLVGEALLAGLaa--------hPSEVHATAVRPDMpav------------------------ 58
gi 116670801   2 KIIIDARFTrld-hhDGISRYGASLIAATakiad-vsmliSDSRQLALLPDVPytl------------------------ 55
gi 148272894   2 RLVFDCRYTrig-rhDGISRYGAELVARLgarfdvtmlisDHRQLALLPDLPWql------------------------- 55
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815   67 srievatdayrrLSNLAKARALhgq-------------------rpALFHGCNYYlp-------ayDGPSVATFHDISIY 120
gi 13932334  144 vlaaqyrvlplaMATLHRLKISlsgllrv-----------krfkkiETRDFDVFIsqtpfpgvlssNTKLIVRYHDAIPI 212
gi 159028564  67 yidkliifpvqlRQQLDWADIVcic-------------------dqALSYLTPYLk----------DRKYFIICHDLLAI 117
gi 62423868   69 -----crwvklnSPTSAKEVVIakkln---------------dlgaDVVFSTMQVmgs-----tgrRYGLILTVHDLIYY 123
gi 148927306 101 -----idytilnNPFSPRELFMgytln---------------klgaDVVFSPLQYmgg-----lgrKYKLILTIHDLIYY 155
gi 149279791  62 -------fkfvqLNAAGRMKRLmteypr------------iikeggYDYAHFQYIvpf------vkNCKFINTVHDLLFL 116
gi 134097289  56 ---------kinSPFSPRELWVsrtln---------------klgaDVVFSPMQVigg-----fsrRYKLILTLHDLIYY 106
gi 108761847  59 ---------lrrLPRAGARNAAfnadrlltrfglypgrallargrhDAFHVVDHTyaqlv--halpASRTGVYCHDLDAF 127
gi 116670801  56 ----------inSPLSPAELFVagkvn---------------klgaDVVVCPMQTmgt-----fgrKYGLVLTLHDLIYY 105
gi 148272894  56 ----------vsSPTGAREPWVarrvs---------------rmrpDVVYSPMQTmgs-----rgrTYPLVLTLHDLIYY 105
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815  121 RWPQCHrad---------rvrYMRKELALAVQRAQLILTVSDFSRREIAAHFalpLERIRAIPLAADaafrphaqaela- 190
gi 13932334  213 FLPHTIkdra-------fhhgAHYDALARNVRSGAYFACVSAATRNDLLKIFpeiEDRAVVIHNTVSpiyseidspkelv 285
gi 159028564 118 RSALGEipenpt----swtgkQYQAMILRGLKQAKYVVCSSEATRADVLRLTkiaPEQTEVIEDCLNqgyspmtkeaav- 192
gi 62423868  124 SHPLPPadlpaavrllwrayhLSFAPQRLLLGRADAIAAVSQTTKGLIADHRl-sSKPVTVVSNAAEvavagsr------ 196
gi 148927306 156 RHPKPPgflplpvrmvwrlyhLTFGPQRWLLNRADHVAAVSETTKRYMLKHRi-tKHPIDVVYNAPQetflrpt------ 228
gi 149279791 117 EFKQYFpws---------yrvSRKLMFYASAKRSDLILTVSDYSRIDVAKKFgikISDIHVTPNAVSpaepsdvn----- 182
gi 134097289 107 RHPQPPgflplpvqvvwrlyhKAYWPQRVLLNRADAVVTVSETTRTLMRSYRl-tRRPITVVHNAPSeldssvsvkdsvd 185
gi 108761847 128 RSVLEPrrepr-----pawfrAMARAQLAGLERAAIVFHSTQAVRMELLAHGlvpESRLVWAPYGVSpeyrpvptpgapd 202
gi 116670801 106 EHPSPPgflpapvrvlwrlyhKAYWPQRLLLDRADVVATISHTTEALIAKHRl-tRRPVRIVGNAPQhghtprd------ 178
gi 148272894 106 RHRRPPrdlpapvralwrafhLAWWPQRLLLDRADAIVTVSETTRGLIRAHRl-tTRPVVVVPNAAElapapdghp---- 180
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815  191 ----------------------------aplqalglqtdAYCLCVSTIEPRKNIDVLLTAYAALPAavr-aryPLVIAGH 241
gi 13932334  286 kdivssrlfrplakkykalssshvdvftrsrlnadqqdfEYLLMVSTVEPRKNHTSLVAAWELLRSrhn-ealKLVLVGD 364
gi 159028564 193 ---------------------------alvgkfninrdyPWLIHVGGRQWYKNRLGLLKIFKRLITfsglencRLILMGK 245
gi 62423868  197 --------------------------------svnrhdaRSLVYMGSFLPYKNVETLIRSLQHLPGw------TLHIASR 238
gi 148927306 229 --------------------------------klqktptKDIVFMGSFMPYKNVECLIQSLEFLPGy------TLHLLSK 270
gi 149279791 183 -------------------------------ilekyglkKYLLYVSRFEPRKNHIGLLQAYLKLKLyeq--gyHLVFIGS 229
gi 134097289 186 sgrge----------------gaveraagedarngaggpRELVYMGSFMPYKNVETLIDGMASLPGy------RLHLVSR 243
gi 108761847 203 ---------------------------aseavlaplggrPYLLHVGSAIPRKRLDVLFAVFAALRAry----pELRLVQQ 251
gi 116670801 179 ---------------------------------pgagadRTLLYMGSFMPYKNVETMVRGMAELPDm------TLHLLSR 219
gi 148272894 181 ------------------------------dgpreapaeRTLVYMGSYMPYKNVETLVRAADDLPDh------ELHLMSR 224
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21240815  242 SGWSSEAlharm----rsaeQAGWLRYLGYVpQDGLPALVAgARLFVFPSFYEGFGLPVLEAMASGTPVICASasSLPEV 317
gi 13932334  365 LGWDYAEfvdai----vpwvERGELFLLSNVaAPDLRDLYKhAKVTICPSYAEGFDYSGVEAMMSGGVVAASDipVHREV 440
gi 159028564 246 LLLPDMRefvn------qnnLSAQVIELGTVsDDDLRAFYClATALIFPSFQEGFGVPVIEAQSCGCPVFTSNrlPMTVI 319
gi 62423868  239 IHGRREAalra------lipDRAKVIFHRGVsDEEYAGLLEgATALVTASQEEGFGLPVIEAMAQGVPVAISDiaIFHEI 312
gi 148927306 271 IVPERKAelle------lapKGAKIKFWNGIsDEAYCALLAhATALVSASKEEGFGLPLVEGMMQGVPVVCSDieIFHEV 344
gi 149279791 230 KKEQIELnayeelqklihadARPFIHFKEKLsWPDLNAFYQqADCFVFPSLAEGFGIPPIEAAMNGCKVLSSNq-TAMSE 308
gi 134097289 244 VAPAREAelvr------ripPGADVIFWRGIsDGDYHELLSrAFALVTASKDEGFGLPIIEAMNVGTPVVCSDltIFREV 317
gi 108761847 252 GGALNGTqraqv----ealgIGDALLQPPRQeRATLAGLYRrATAVLVTSEAEGFGLPVIEALACGAPVVASDlpVLREV 327
gi 116670801 220 ITPQRQAelea------lvqPGANVVFHNGVtDAEYEALLGrTTALISLSRAEGYGLPLVEAMSHGTPVIASDipIFREV 293
gi 148272894 225 VGSAERArle-------glaDGARLVFRDGAsDDEYALTLRhATALLTASRDEGFGIPVIEAMSVGLPVVVSDipIFREI 297
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21240815  318 AADAAMLFDPadVSALTLALARg----IDDSDWREAARQtgl--------qrAAQFSWQRCAVATAD 372
gi 13932334  441 YEDACIYFNPysVESIVGGIREai--sLRNASETFAEYRrcakrisarytaeAISPRWDEFIQSVGS 505
gi 159028564 320 ADDAAVYFDPteHEAAATIIAEn----LLAPDRLEDLRQkgf--------inATRFTYERMIQSYDQ 374
gi 62423868  313 AGDAAVYFDPddAGDVAAGIAR-----LTDAKLWSELSAagq--------kqATSFDWNSSAQALIG 366
gi 148927306 345 AGKAALFFDPnsPKECAKQIHK-----LENPKLRAELIKkgp--------kqASKFSWDNSAEALLA 398
gi 149279791 309 FSFFKYLFDPndQTAFENQLAAv----LADDNYPFEEIKea----------iTNKYNWQVIAENFYH 361
gi 134097289 318 TGGHARFFQPdsPDGFAAAIDG-----LEDGAVRAELVEsar--------vqAKHFTWASSAERLLE 371
gi 108761847 328 GAEACTYCPVgdVPAWVESVTAllaghDTQPSREARLTR-------------ASRFTWSAHARTVLD 381
gi 116670801 294 GHDAVSYVHPdsPSEFANAVRRl----EEPEVWKAHSLRsv---------erAAEFSWDHSARQLVQ 347
gi 148272894 298 GGDAAVYVDPddAEGFAAAVRA-----LEDPDEWRRRSAaci--------arAAEYDWDRSAEALGD 351
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