Conserved Protein Domain Family
GT1_UGDG_like

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cd03817: GT1_UGDG_like 
This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Statistics
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PSSM-Id: 99987
View PSSM: cd03817
Aligned: 67 rows
Threshold Bit Score: 296.455
Threshold Setting Gi: 23335711
Created: 15-Dec-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                      #                                                                 
gi 14043013    2 RIGIFSEaYLPLISGVVTSVVNLKEGLealGHEVYVITPIPSKdkfendpSVIripgwv------iprksLKGFRLVLFV 75
gi 115361663   2 VIVLVVDsFENKSNGTSMTAARFCKALrehGHSVRVVAPFVQGegfyalkERYiplv---------tklaHKQHILFGKP 72
gi 42519196    2 KILIVIDdYFNKSNGMSISTQRFVHEFkkmGQDVRILSSIAGGepdyslpIMTipif---------kniiAKEGFHFAKP 72
gi 32262225    2 IIAIVVDsYKDRSNGTSMTAFRFARALierGHCVRIITTNPTQeesneqsSGEefyfvkeryipivteisHKQHMIFGSP 81
gi 15645049    2 VIVLVVDsFKDTSNGTSMTAFRFFEALkkrGHVMRVVAPHVDNlgseeegYYNlkeryip----lvteisHKQHILFAKP 77
gi 125974034  31 IITLVNDtFNINNNGTTISAMRFAEALsqrGHQIRIITCGDPLksgkdpdTGFemfylpelkipiasrlaHKQNTLFAKP 110
gi 23335711   15 TIALVVDtVGNQGNGTSNSALQWAAELerqGHHVRLVGIGAPEyparvnkVPLvsw------------vaAKQLMQFAEP 82
gi 147920496   2 KIAVFTDtFYPQVNGVVNAIRNFNSQLtarGHEITVYTSGKKPgvskmdgAEVrryia-------ftlppYPEFEPSPNV 74
gi 148927305   2 KILIAADlHWPTINGVATFSRNLAHGLaarGHEVVVVAPSQTGrpyqetdRNHtvmrtta----lpfpfyQNFRISVRPQ 77
gi 45657618    2 RILYFSDtFLPKVDGVAISMRNFADLLakrGHTFAICCPKYGEgdfdslgDGIrverfrs----gylpsyPDIKVVLPSP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 14043013   76 KRYVrkMRKLKLDVVHIHTEFSMGKLGLAVAKkERIPSVYTLHTSYQ---DYTHYVSKLLTrfapnaakkl--------- 143
gi 115361663  73 HEKTlrQAFEGADIVHLFLPFKLEKVALKVARaMKIPFVGAFHLQPE---HITYNMRLQNLgwlnrllf----------- 138
gi 42519196   73 RKEIikDAIRWADLVHLEDPFPVCWSAAKIAKqMRKPITGTFHLYPE---NLTASVPVLDHasinsafm----------- 138
gi 32262225   82 DSHIleSALKGCDIAHFYLPFALEIAGVHLCRkMKIPYISAFHLQPQ---HISYNMNMNFKwfnaylfr----------- 147
gi 15645049   78 DEKIlrKAFKGADMIHTYLPFLLEKTAVKIAReMQVPYIGSFHLQPE---HISYNMKLGWFswfnmmlf----------- 143
gi 125974034 111 VRSIlkKAISGSDVVHIYQPWPLGSAAQRVARqMNIPAIAAFHIQPE---NITFNIGLKRFspaahlty----------- 176
gi 23335711   83 SDTLfrTAFQGVDVVHIYMPFKFGRRAAKVAHqMGIPVTAGFHLQPE---NVLYSAGPLRRipgissfly---------- 149
gi 147920496  75 IGPAasAIKFKPDIVHAHTQFMMGYSAWMAAKrLGVPLVGTFHTPVD---EYVMYVAKHSKmsqrllkri---------- 141
gi 148927305  78 NEVRriIEDFQPDVIHIQMMMGIGRAALGIGKkLGIPVVATNHAMPE---NLLDNLKLLAPfarpigyim---------- 144
gi 45657618   78 TKIKriIKEFEPDLVHIHTPGLLGLYGINATEkYGIPTIGTYHTLMSeqeMYLSFYRLLKLdklflrvsksnkklkmkdl 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 14043013  144 ---------------agkinnqytKNCHMTIVPTkk--iyDKMIRLKHDge-----fTIIPSGINLKPFykssytseqvq 201
gi 115361663 139 ----------------wwfkqsyyQHFTHIHCPSpf--ikSELIKHNYGgk-----kYAISNGFDPMYAprphn------ 189
gi 42519196  139 ----------------rlfrdttfNYCSYLQCPTsk--veQRLKKYNFKsk-----lIVISNGISDYYLqnnqk------ 189
gi 32262225  148 -----------------rfykafyRYTHHIHCPSqlmeeeIQKAGYGGKk-------FVISNGFQINRAqscvk------ 197
gi 15645049  144 ----------------swfksshyRYIHHIHCPSkf--ivEELEKYNYGgk-----kYAISNGFDPMFRfehpqk----- 195
gi 125974034 177 ----------------flfylffyRRFSHIHCPSkf--iaAQLRSHGYKar-----lHVISNGVHPAFCapakp------ 227
gi 23335711  150 ----------------wlfkhwlyKHIDHIHVPTem--taSLLRAHGYKak-----lHVISNGYSPVYSpkkpad----- 201
gi 147920496 142 ---------------areyqdffyKRCDIIIVPA------PSAAKYLHVknk---piVTVSNGLNLSRYgpegree---- 193
gi 148927305 145 ----------------keygarfhNNADFVTLPTe-----AAIKMFGSKaenmkvpmVAISNGIDLKRFslkkppkti-- 201
gi 45657618  158 gkiekfdkfnirkkiilkisnniyERCDLIISPShl--ieKQLREFGLKtk-----iAVISNGLDLTSFkgsi------- 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                         ###                                                            
gi 14043013  202 alkdklgirnDEFVAILVARIAKEKSIGDLVEAFVEFyksypnSRFIIIGDGPDKPVLdklidskkaSKYINTLGFVKNA 281
gi 115361663 190 ------tksdDLYHIAMVGRYSPEKNQRVLIEAAHLSkha-akIQLHLKGQGPQLASLqkh---askLAHRVDFGFLEPD 259
gi 42519196  190 ------ttttDPFTILSIGRFSNEKDQKTLIKAIGRSkyk-drIKLILAGKGPLKNEYisl---cqrLKINAQFGFYSRN 259
gi 32262225  198 ------pfddTFFHIISVGRFSKEKRQDILIKAITQSkya-nnIKLHLHGIGPKEQYLrklc--dklLINPPEFGFIDNN 268
gi 15645049  196 -----slfdtTPFKIAMVGRYSNEKNQSVLIKAVALSkyk-qdIVLLLKGKGPDEKKIkll---aqkLGVKAEFGFVNSN 266
gi 125974034 228 -----rehtfKPIKILMIGRLSPEKRQDVLIRAVMKSrya-drIQLYFAGSGPWEKKLrrl---gnkLPNPPVFGYYNRD 298
gi 23335711  202 ----pdasapVPFRVIASGRLASEKDQITLIKAVSMSrha-gdIQLVIAGTGPLKQYLkfra--grlLARKADIGFHKHA 274
gi 147920496 194 ---vrkrfglTGPVIMHGGRLSYEKRIEGVIDAMPLVlekvpdAKLMIVGRGPAMKFLecrvkalgiEQSVVFTGYVSDE 270
gi 148927305 202 --fkkfglpeNKPIITYVGRLDTEKHVSVLLEAMRRVlet-ldAHLLVVGSGNDSEHLhelagqlgiAGQVTFTGRVSDE 278
gi 45657618  224 ------kqlgSAPKLLHVGRISYEKNCDVILNSFKLIhdeipdSTLTIIGDGPALPSLkvqaqnlgvENFVTFTGFIKRE 297
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        #                      #                                                        
gi 14043013  282 EVGLYYQiADVFLNASTTETQGLTYVEALAA-SLPIIVRYDDVFDAFVEdgkNGIFFNkne----------elvKHLIHI 350
gi 115361663 260 ELVKLLYqCDLYVHTADVEGEAIACLEAMACgIVPIISDSKISATNQFAl-dDRSLFKsndprd----ladkidWWLDHP 334
gi 42519196  260 DLKQIMDqSNIVVHCANVEVEGMACMEAFATgCVPIIAQSPLSSTSSYAl-sPNNLFPag-------------rSEILTQ 325
gi 32262225  269 ILIEKLKcCHLYVHSAEVESEAISCLEAVSIgLVPVIADSKISATTQFAl-dERSLFKtnniadls-akidywvEHSKER 346
gi 15645049  267 ELLEILKtCTLYVHAANVESEAIACLEAISVgIVPVIANSPLSATRQFAl-dERSLFEpnnakdlsakidwwleNKLERE 345
gi 125974034 299 ELIKLIHeCDLYVHASDAEIEGISLIEAFACgLVPIISDSKQSAAAQFAlgpQNLFKAgspe---------slaEKIDYW 369
gi 23335711  275 DMPDLLRsGDLFVHCSIADIESVSVIEAMACgLVPVIAASELSAASQFAl-iDESLFPvr-------------dAALLAR 340
gi 147920496 271 DFPKMFAaADVLAINSPVETQSLIVLEAMAT-GLPVVGADSAAIPDAVVsgeNGYLFKpdds--------kalaEHLTRI 341
gi 148927305 279 DIVELHRtGKVFCMTSPVELQCIAMLESMAS-GLPVIGVDSGALYELCHdgeNGFICEtdnd--------aeiaEKIIIL 349
gi 45657618  298 QLPEEYPkYDLFLTASTMETQGLVILESVAC-GLPAVGVDSFAIPELIHdgkNGYIAKpfdi--------kgiaEKAISI 368
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
Feature 1                                                        
gi 14043013  351 RQNPeil-------gtLSKNAEISTKPyake----vyaKSCETLYLDL 387
gi 115361663 335 EERLqae-------drYVQNATRYTLDka--------iEQALAMYQEV 367
gi 42519196  326 RIDYwinhp--kdlkvMSTNYQNYAKSltve----fsaKKVLTMMKNA 367
gi 32262225  347 EQMKe----------qYAKSASKYALE-----------KSIDKIINMY 373
gi 15645049  346 RMQNe-----------YAKSALNYTLEns--------vIQIEKVYEEA 374
gi 125974034 370 LDHPe-----------QLKEAEKKYAQlgkqyalehsiRKIEKVYSSM 406
gi 23335711  341 RIDWwi--------ahQAERAEWGEKYa----------EYTKAHYSVE 370
gi 147920496 342 LTDGelr-------akLKAGALRTASEhs-------leKSADKLLKVY 375
gi 148927305 350 LTNEklr------kkmAKKSLEIARTHdlq-----hvlNEFEKVYAYV 386
gi 45657618  369 LKDPvlyekfskeslkISKSHEMNSCV-----------DKMEEVYKTI 405

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