Conserved Protein Domain Family
GT1_ExpC_like

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cd03818: GT1_ExpC_like 
This family is most closely related to the GT1 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).
Statistics
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PSSM-Id: 99988
View PSSM: cd03818
Aligned: 44 rows
Threshold Bit Score: 349.209
Threshold Setting Gi: 39982859
Created: 28-Dec-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                   #                                                                    
gi 1890594     4 HVAFVHRRGFGQFAALARHLAEA--GNEVTLVTETVDQRIPs---VRVVRHRAepgpqpn--phiarhLGVPDHHVRIGH 76
gi 148238455   2 RLLLIHQNFPGQFRQLAPYLLKQ--GHDLAAICSHQRPVPMp---IQLLRYTPpskvkg----lqhfgGSMWLEALQRAE 72
gi 148238457   2 RILFSHNNYPAQFRRLIPALIEQ--GHEVVFLCRSKEWHAPe---LDGVRLLPfephragggaaihpyLRRFEAAVLQGQ 76
gi 78183693    2 RILLIHQNFPGQFKHLVPYLSSF--GHDIMCICSHDRPFAHw---IQGWRYKPpeppke----pmplsQHLWFESLQRAA 72
gi 78183695    2 RILVSHVNYPAQFRRLIFHWSQS--GHDVVFIARQSEWHSPspkgFRVYFYENtrssnt---islhpyLNRFESAILEGQ 76
gi 78483937   12 RILFLHLSGPGQFEFLGRWLAGQ--GWDVTFMHGGIDADPA----HDGIRTRRfalrdttiptgdprhILDHAAQNCRGA 85
gi 157408723   3 DFLFVHSHFPGPFGFLAEALMGR--GHRCAAIAAEGAPGLPg---LPILHWRPgrkvt-----pglypLAHPTETAFINA 72
gi 33864943    2 HLLLIHQNFPGQFRDLAPAWLAS--GHQVTAIGSMAEAPSGl--qWQGLTYLQy-------------cFEQAPSQLQRGL 64
gi 33337561    2 NLLFIHGNFPGQFKDIAPALALNtnGKTYFLSLSDNPQNIVlp-rVQFRQFKLhrdvgs----ethayVQSAELAVLKGQ 76
gi 124021839   2 NILFVHGNHPGQFRSLCGALGESk-DHKVIYLTEKDYENVDhidgVETRSFKQhrlans----tthhyLHTTEECILKGQ 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 1890594    77 RVAETFDamg-rlGQSPDIVLGHiGWGSMMFVKDVlPRVPALGYCEFFYRS---EGADVGFAPDDRPDse--------tr 144
gi 148238455  73 SVTHAVAall-akGWQPDAVLAHsGWGETLGISELlPDVPQVIWPELWVRP---EHGGHGTDPGLPQKl----------- 137
gi 148238457  77 ATYRSLQplv-qeGWAPEWIINHvGFGNGLYLSDVfPNARRIGLFEWYYNA---CGADVDFLKRGPVDpd--------ra 144
gi 78183693   73 SVADICHkln-tqGWVPDRILAHsGWGETLGIAETwPNIPQIVWPELWTLP---QHGGYGFDPTLPEVsfsqtieqlgrn 148
gi 78183695   77 SVFRIARqlr-dsNWIPDIVISHlGFGNGLFLSDCfPHARRIGYAEWFYNS---YNSDVDFLSSEVVSd----------d 142
gi 78483937   86 TELMFRMrh--seGYVPDVVVAHaGWGVGLGVKLVwPDCTYVAYHEWYYTDr--NWDKRRAEKPADLAvm--------is 153
gi 157408723  73 TAALRCAldlrkhGFDPAVIVGHpGRGETLLLNQVfPRARRLAYAPYYRAEg--DALGFDPEWTRPPNl----------e 140
gi 33864943   65 AVARLVEqll-dqEHPPDLVMSHsAWGEALCLQRVcGDVPLISYPELWGNS---RSLGFGFDQDLDGFepdat---sfss 137
gi 33337561   77 AVLRALDqlhkqeGFMPDVVICHgGMGFGLFVKSLlPNVRLISYLEWYFTP---SNSQELILNPSINDf----------- 142
gi 124021839  77 ALIKEIDlll-adGFCPELIIFHgGMGYGLFINELlPHAKTIGYFEWWFTSktsQHLCNSIDYDTRFK------------ 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 1890594   145 KRLRlrni--aqllSLEAMDGGISPTNWQKSLYPADar-qRIAVCHEGVDTRRfRPDPAASLKLPDgrv----------- 210
gi 148238455 138 EQLGrhal---trvALAEAQAWVLPTRHQANSFPSEfqgsRLHVVHEGIDASVaCPNPLVRYSVRDcsi----------- 203
gi 148238457 145 LRLRtwna--hlllELAACDFAVTPTRWQRDQFPKHlr-sHLRVIHEGIDVDGmQALRQSPPIRPAclp----------- 210
gi 78183693  149 LMTRl---------ALNQAAAWVMPTHHQADSLPACfqdsRLNIIHEGINTSIaSPNKNVSFYVRGrhv----------- 208
gi 78183695  143 HRLKlrcwnseillEMSTLDYLIVPTCWQKSQFPSIyh-nQISVINDGLNLPLlSNIKHANSVDFNflp----------- 210
gi 78483937  154 DRMRnlp----itgEFDLADASWCPTLFQASRFPPVlr-rQITVMPDGVDCDLhRPDPQARIDFDWlrl----------- 217
gi 157408723 141 DRLRdragnaalamVYAEAERLVCPTEFQRGLLPSGlr-aQASVIHEGIDTDEvRYDPEAALRLPSgrv----------- 208
gi 33864943  138 ANLIae-------lAVFQSSAAVVASRSQLLSFPPDlq-qRLTLLPEGVDLERiMPDPNACLELPEqale---------- 199
gi 33337561  143 CRLEcrni--pilqEAAQADQLVCPTRWQRDQFPAFir-dRIQVVFDGVDLDFfSPGPPADPLVLNanresp------lq 213
gi 124021839 144 NDMRnlv----ilkELANCTRAVVPTEWQKNQFPNLae-gKLKVIFDGVNEYFfHEDTLRHDADSIktiligeelnkplv 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                  ###                                                                   
gi 1890594   211 lkaGDPVVTFVARDLEPYRGFPQALEAAAKVVRrhPDALFVFVGGDG--VSYGAPPPGGg-sWKDHLLASLdv--pRERL 285
gi 148238455 204 -drSVPTITFVNRNLERLRGFDMFMRALPMIQRahSQVRILIVGDNE--SGYAGGSPGGe-pLRQVMLRELqgeldLSRI 279
gi 148238457 211 adpDLEIVTYVSRGFEEYRGFPQAMQAIAELQRrrPGLHALIVGHDG--VAYGAKRQDGr-gWGEWARDELtl--dPSRT 285
gi 78183693  209 -daSVPSITFVNRNLERLRGFDLFMQSLPELQRnwPDLCVFIVGDNG--PGYGNGHPSGk-tLREVMINELaseldFNRI 284
gi 78183695  211 ndpNLEVLTFVSRCFEEYRGFPQAIRTISALQKlrPNLHVIIVGEDG--AAYGHPRSDGv-pWSVWAIKTLnl--dPLRT 285
gi 78483937  218 -paDRPVITYATRGMEPLRGFPQFLRGVARLQArrDDFDTVILANDS--VSYGRPLARGd-sWWLRMIDQLdl--dHRRI 291
gi 157408723 209 ltkARPVITFIARQLEPLRGFPTFMRALPRLLEevPQAEILIVGADG--RRDAAPKGSQpqtWKQRLLSELdgrldLGRL 286
gi 33864943  200 fraGQPLVTFISRDLEPLRGLRQLLKAWPLVSLalPEAQLVLVGGTG--QGYGLQPPKGe-dHFVDALEQLpdtlnREQI 276
gi 33337561  214 ftsDQLLLTYGTRGMEPLRGFPEFMRAAAVAQQtfPQLHVIVFGKDRsaYSYPSPHPSGs--WKQFMLEQLegqldLERL 291
gi 124021839 219 ienKDLIVSYATRGMEPLRGFPEFMLLLPELFKefNNLKVIIGGRDRaaYSYTAPTENGs--WKEYMLEKLkgsvdIERI 296
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                  #                     #                                               
gi 1890594   286 IFPGvVPHSVLRQLFQISAAHLYLTYPFVLSWSVLEAMACGALVIGSDTAPVQEVIRs--gRNGLLVPFFd---TDALAE 360
gi 148238455 280 HFLGrIPHPQLMALLQASWVHVYLSYPFVMGWSLLEAMACGCCIVGSRGMPVAEVIEd--gVQGLLVPMGd---VELLAR 354
gi 148238457 286 HWMGmLQDAEYHQVLAHSSVHLYLTVPFVLSWSLLEAMAAGCALVSSATPPVLEVLEh--dRSALLVDFFd---PMAQAN 360
gi 78183693  285 FFLGrVPYNQLITLFQISWVHVYLSYPFVLSWSLLEAMSCGCSIVASEGMPVEEVITd--nVNGLLTSMDn---PKLLSA 359
gi 78183695  286 HWLGlVQENVYLQVLSVSDVHFYLTVPFILSWSLLESMAVGCSIVASSTPPVMEFLEd--gLSALLVDFFd---VDAQVQ 360
gi 78483937  292 HVNAmRPRDEYVRTLQASHAHVYFTEPFVTSWSLSEAMATGCLVIGSNTAPVRELVRd--mENGLIVDMDd---ADEVAD 366
gi 157408723 287 HFLNrLTHAEMLAALSVATAHVAYTYPFSLSRVFLKAMACECLVIASDTAPVREVVRd--gVNGIIRDFFd---ADALAE 361
gi 33864943  277 HHLGpLPHAAMLTLLQCSACHVALSYPYTLSWSVLEALACSAPIISNPDSPIAVELHkeatDALALVPFNd---AEGLAN 353
gi 33337561  292 HFTGlLNYGELVQLFRRSDLHCYFTRPYVVSWGVFQAVACGARLLVNDFAGIDEVFDg--kPFFSPVDLDh---QEQINA 366
gi 124021839 297 FFTGlMSYENYRSLLRRSDLHVYFTRPYVVSWSLFEAITCRAHMLVNRNGATNGIATd---DSVYWTDLDrleeCREIAV 373
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
Feature 1                                                
gi 1890594   361 TIVGALNrp-dnFRELRGAARRtveq-rfrlDDCLARQLT 398
gi 148238455 355 RVIALLNap-dlRRNLGEAARKeals--wdqSVTLPQILR 391
gi 148238457 361 AVERLLDqp-dlRARLSRAASKkacd--fkaSIGIQSWLA 397
gi 78183693  360 RISQLLSdp-esRTRLSKAARIsals--ydtSITLPKLYK 396
gi 78183695  361 AINTLLSnr-klASRYADAAMNraea--lsfDKATESWDT 397
gi 78483937  367 AMAWVLDnp-gdAADLRRAARRtiladhdaaRVFPAKDAW 405
gi 157408723 362 ALITACRap-erSRPLREAARRtvidrydrrRHCLPTWLA 400
gi 33864943  354 RMIELLEqp-qqARTLGATGRSwierhgglsKAMEGYEQL 392
gi 33337561  367 SVIECLRve-keSNAVSLPSSLslss--ciaQWVDLIFSM 403
gi 124021839 374 NALKLPRqnrkkALLMKDYSLKksl---newSLLINEVFQ 410

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