Conserved Protein Domain Family
GT1_amsD_like

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cd03820: GT1_amsD_like 
This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Statistics
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PSSM-Id: 99990
View PSSM: cd03820
Aligned: 115 rows
Threshold Bit Score: 229.786
Threshold Setting Gi: 154249258
Created: 15-Dec-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.
  • Comment:Based on similarity to sequences with known structure

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                        #                                                               
gi 2498133     3 KLLILIDGIsn---sGGTDRVASTLSSLLsnhNYDVTLYSLNSGe----PYYPVDNKVSIRQPkss------mrLFKLFE 69
gi 160884480   3 NILITFTNAidp-ttGGVERVYHNLVPYFrehGYNVFATYQRKT-----DYDKNSVYTKAIFMey--------sIDNVGY 68
gi 29346762    1 MNILFIDNLepnpllGGISRVISCLASSL---KENYGFVVSHAA-----EKFDKHKQTELDIIlk-------ddQSYIPI 65
gi 153806204   2 KIAICNVQEfnp-tiGGIERVSVSLAEGLikeGVEVLFVACRKSpy--sKPYTLPAKQVLLPKtld------ycIENVQA 72
gi 150003638   2 NILFYTTNEvap-qyGGVERVTANIANALt-tFYNVNCYSAYKYni--dKSFIKQQFVNTIKIn---------sYHNLNN 68
gi 88802230    6 NLLFIYTSEiip-qeGGVQRVTKVLSDYFksqSINVFYISQHKKs---kPSKELSSHYFLPDSnl-------stIENINF 74
gi 91216637    2 NIALFLTQKldp-naGGVQRSSSKLAKIFqsnQHYSIIISVGNHa----TAQEDFEGITLYYIn----------IKDENQ 66
gi 160887498   2 NVLFVEESLdp--slGGIERVTYCLSKYLtkrGIGCYFIYYQNDypkieKQYKLKVDLKRQGC-----------KEFKIE 68
gi 149372426   8 KVCIVTISLa----kGGAERSTAILSQMLdsqGFDVHLVTLTNE-----IVYPYAGKLFNLGVfkdqqdntlsrLSRFKQ 78
gi 161322878   8 KICIIVDCLs----gGGAEKQAANFSKSLhkyGFEVSIISLKNQi---tYDYEGTLYNLGENEasik---iikqIQKFFA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2498133    70 FIRYAKn---TRPDGVMIIsmg-----klsVQALLLSKl--------FRVKSRLICCDHvsietlsaavr---------- 123
gi 160884480  69 FDKLDKvmmeMAVDIVICP-----------FPSYQLFNycsr-lidkKVFFHVHNVPSKlmypssaklpnilkesfvdrc 136
gi 29346762   66 LRQFLIn---KDIDIIVNMrptyc--vgiiNKAKADLKc--------KYIIEYHSTPFYarkdkkfafkrllrydikqep 132
gi 153806204  73 LAHILKe---EKVDILLNQnshs----elyNRTCYEVKsls----gvKLISVLHFSPDMrikgnrnlvsfkylslkenii 141
gi 150003638  69 LIQFIEq---NKIDVIINQge-------hkLTKSLRLAlnqsqnkkcKLMFALHVSPATeinfitldnpkkelkegknir 138
gi 88802230   75 LKNIVSn---KEIDVIINQaal------ggYMASFCDKaklv--rnvKIISVIHNSLLGnvenlstsnkkifnkvplsaf 143
gi 91216637   67 LKIILEk---EAVDFIINQkgy------slSLTKLLLKnkp---lktKMINTLRINPLNfygnhkdiikelfkskkidfl 134
gi 160887498  69 VLSFVEk---NEIDVVINQdqyhw-rlemiYRELINIGs-------cKIINCFHLSPDYfkynkltikgklknvvykl-- 135
gi 149372426  79 LRKYLKq---EQFDLIIDNrnrqsalkelyYLNYIYRKq-------kIVYVVRSFNLDQyf------------------- 129
gi 161322878  78 FKKVYRk---SNADMYIDFrsr-----srfFMEYLLHKyif---eakKMIMMVHSYHTEwhipkgkt------------- 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2498133   124 ----------------------klkvfcyglaEKVVVLTqhdk------------nyltSAFSLKNVYVVGNISPFHHEn 169
gi 160884480 137 -----------lkrirfdlrylasfrrielnkMKIVLLSdffrd----------dlksfYDFNPKCICALPNPFCIDEEy 195
gi 29346762  133 frysiklllfplwyhlsylrvsklwkrnyinaDKYILLSnnyidd---------fvnefNIIDASKLLAINNPLSYKEFl 203
gi 153806204 142 nllrd-vctrfplryifmydqcrmyknlylnsDRIVLLSnefkes---------yiklsGIKESSKLTAINNMLSFPYEm 211
gi 150003638 139 knisk-flsfpyqkirkiiklpilyresyhfaDKVILLSshfkkp---------fleysHLKDDSKIRIIHNALSFHSFy 208
gi 88802230  144 sflldtvffkifllgvyklkyklkylnlynlsDKVVLLSdnyfke---------lkffvKKADKNKVISIANPCTIQSPl 214
gi 91216637  135 nifl----trkfilgyhilkqnielrfivkntDAFVMLSerfkpel-------fflapsLKKFDAKIFGIGNPFQRPKLd 203
gi 160887498 136 --------------ftgytpdvyvrkknyelcDRFVLLSqnfmnd---------finlyGVTDTHKLISISNPLSFDESl 192
gi 149372426 130 ------------------------------pkLKVVSQLmvkravkivgvaeavseavnTKFNTNKAVTVYNPTPQFKTs 179
gi 161322878 134 ------------------------fkkiyneiHAVVAVSeaie------------dklgKEYDFENLLSIPNYITAVERn 177
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                          ###                                                           
gi 2498133   170 slnrfddvfarKQNRVLAVGRLTY-QKNFGRLLDIWKNVh----KQGWKLLIVGDGEEKAELlekiKKYHLEESAEIVSp 244
gi 160884480 196 qld-----yqkKEKMILYVGRINTrQKRFQSLLNIWKRLqn--eLLDYRLEIVGGGPEKELYen-lAHEMRLKRITFHDf 267
gi 29346762  204 pis----rlqnKQKRVLIVSRLWN-YKRIDMSLEIWKLIee--qVGDWELRIIGDGPEEEYLrrlvCRYNLKRVVFVGN- 275
gi 153806204 212 nn-------yqKKKQLLWCGRLLFsQKRPDRILLVWKKLqe--qLPDWNLVIVGDGPFSNEMkqlsKKLSLQRVEFAGF- 281
gi 150003638 209 dla----nynhKKKEVLIVSRLEEePKRISLALKIWKEIetdhtLSEWKLKIVGHGKMESWYkslvIHYGLQRVFFEGT- 283
gi 88802230  215 dte-----layKENELLYVGRINTsQKRVDLLLDIWDKThk--sFPNWRLTIVGDGEELISLkhlsKKMNLERIHFLGH- 286
gi 91216637  204 ia------tldKENIVLFVGRLNVpQKRVDLLLQIWKKLhg--eIPDWKFWVVGHGEERNKMeafcKAHKLDRVIFFGK- 274
gi 160887498 193 din----visqKKKQVLIISRLQEsHKNICSALRIWKRIed-yqIFDWKLVLAGYGRDEKLIldymSQLELKNVCYVGRs 267
gi 149372426 180 ktp-----spfKEKYIIFLGRLVEnVKNFTLLLEGYKKSni--sAANVHLKIMGEGQDKNFIldkiNELNLSKTVEILPf 252
gi 161322878 178 qee----nsivKDEYIIAVGRLQNdIKQFDRLIETYHASkl--aEKGIKLFICGEGDDKKALqkliTDLQLNEHVKLLGf 251
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1           #                     #                                                      
gi 2498133   245 sKKISEYYRSSGVIAMTSRYEGLPMVLIEAKNYALPAIAFDCKTGPAEIIKD--DGYVVDYQsnELFTAQLNQliASEQL 322
gi 160884480 268 -QNPTEYYKKAVCSCMTSNYEGFSMVLIEAMQYGCVPFVFNSFASLPDIIDDkvNGYVITPFdeGEYVQKIKEf-ILLSK 345
gi 29346762  276 -TEPKEEYEKASLFISNSAIDGWMITLTEAQQMGTVPLVMDSYKAVYQIITNheDGIIIQNNnvDEFAIQLLTlmKNDVK 354
gi 153806204 282 -ANPIKYYKESSIFCLTSNHEGWGLVLTEAMQFGCVPIAFDSFESIHEIIEDgkNGFLVKPFdiDKYADKVLRlaDNFKV 360
gi 150003638 284 -KNPEPYYNEASIFMMTSSFEGWGLTLTEAQQYGCVPLAFHSFASLTDIITDkvNGFAIPNDdiSLYIKQMKLlmTDEKL 362
gi 88802230  287 -KDPTPYYTTAKILCMTSSFEGLPLVLAEAHNFNVIPILFDSFPSATDIIKEgkNGFLIKPFdlDAYAVQLGKlmTDYNN 365
gi 91216637  275 -DNPNEYYKRAKIFHMTSAYEGFGNVLVEAQSFGCVPVLFNSYAAALDIVIHneNGILVTPFniDKYVEETKDliMNSSK 353
gi 160887498 268 -KNPQKLYQESKIFMMTSNFEGFGMTLTEALQNACVPFVFNTFSSLHDIIESdyNGFIIPAKdeILYATKMIEfmQGKNQ 346
gi 149372426 253 tPNIQPFVAHAEFLALTSHYEGFPRVLIEALSQQTPIVSVDCKSGPSEIVVPekNGILVPNYdaEALGKAFTKmiNEPDF 332
gi 161322878 252 vENIAEYIKNAKYLVLSSRVEGFPMVLLEALQQKTPVIAFDCKSGPSEIIQHkiNGLLVEDQnfANLKDAMLLliENMEL 331
                        410       420
                 ....*....|....*....|....*...
Feature 1                                    
gi 2498133   323 RKNFAqaa--wqNSADYGPELILKKWND 348
gi 160884480 346 KNKEIisvkameKSREFDVRRVGQRWIE 373
gi 29346762  355 REEMAkaa--ikNSKRFAVENIVAQWVE 380
gi 153806204 361 DYVMNvm----nSMERLMPENVVKLWIR 384
gi 150003638 363 RKSMSana--ieSSKQFSIEIIIKKWME 388
gi 88802230  366 LSPSLneq-caiSAKKFSLDRIGNKWLN 392
gi 91216637  354 LNQLAvng--yeHVTKFSYEESYKKWDR 379
gi 160887498 347 DKYAVqa---leSSRKFSIENIGLQWIH 371
gi 149372426 333 LLHCKnna--lsSIAHLKQDYIAKQWRQ 358
gi 161322878 332 YMNCKqnt--vsSILKFTEKPVIQQWIQ 357

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