Conserved Protein Domain Family
GT1_Bme6_like

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cd03821: GT1_Bme6_like 
This family is most closely related to the GT1 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Statistics
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PSSM-Id: 99991
View PSSM: cd03821
Aligned: 40 rows
Threshold Bit Score: 244.908
Threshold Setting Gi: 78355640
Created: 15-Dec-2005
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative
Feature 1:putative ADP-binding pocket [chemical binding site]
Evidence:
  • Comment:Some of the residues involved in ADP binding bind indirectly.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                        #                                                               
gi 5478236     2 KIIHVIGSYd--pAKGGPQAVVVRLAAAqaSLGHRVTIVSYSDDavsrraaeatami---pdfdkvqtlllpMPDIYETF 76
gi 84488886    2 NILQVIPYFa--fKRGGDVNVCYNLSKQltSMGHNVTILTTTFEynkedtdlvd---------nltmvpidyEFNLALFI 70
gi 119962757   2 KIVQVVTLVspdgAYGGPVRVAQNQSTElsKRGHQVQIFAGARGavdpsyfgpgv------qtrlfkalriiPGTGFAGL 75
gi 118470651   2 RILQVVTLFspdgLYGGPTRVALNQSAElaGRGHEVTIAGAARGyealpselngv------pvklfaatnilRRSGFAWT 75
gi 21227281    2 RILEVSNYFkpswETGGVTKVNYELSRGliEKGHEVTVYTTDGYasrldvpknkpvcvdgirvyyfynlfrsLVKKMKFP 81
gi 126178628   2 KILQVTPFFkplwESGGVARVAYDISRTlhENGHDITVYTTNRSiypndlptnrltsvdgmdvyyfenlrkyALGVTPPV 81
gi 73667585    2 KILQVTNFFkpswEAGGIARVAYEISKNlvQQGHEVTVFTTDGFksrlktiknkpvnv-dgintyyfrnlsnYLTKRNIV 80
gi 2621430    14 RILHVTPYFkpswEAGGPPRSVYDLASRqvSAGHEVTVYTTDGFkrrldvevnrpldvdgirtyyfrnlsmyLAGNMNLP 93
gi 126180331   2 KVLQVIPRFn--pSLGGGVDVAYNLSKHlaLRGHDVTIATTDYLfdadyaatike-------igvevipfehLFNYCLYI 72
gi 153891177  64 DVLHIVASLd--pAHGGPSQSVLALACAqaAAGARVCLAALDYRprsippg---------------gitlqiATGNAPRL 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 5478236    77 TGGhtanavTALIRGADFVHLHGiWETNLLRASMlcrrfHIPYCVCCCGMLDGAafiHALNRDEIELMRPLgl------- 149
gi 84488886   71 YSPkmkkwlDKNITKYDIIHLHElRSYQNNIVIKyakkyNIPYVLQPHNSTPKHv-tKTLIKHIYDIFYGNniiqnattt 149
gi 119962757  76 SAPamlpslWHALKDADVVHLHLaRDLVMLPAALlclirRKPFVVQTHGMIDES---NKKLARILDTLVTLrvlrsskrc 152
gi 118470651  76 YAPgltswlRRNWREFDTVHVHLaRDLVTMPVAAvvrrrGIPYVLQTHGMVVPT---NHSLATPLDRMWTHdilrharav 152
gi 21227281   82 TPYyapfvlRGEIRNFDIIHIHEhRTLLAAFVRYyakkyDVPYVVQAHGSVLPSf-qKQKFKHMFDFFFGNqilkdatnl 160
gi 126178628  82 MPYrmpavaRRETDGFDLVHIHDhRTMLTIIASHyarkyGVPYVLQAHGALPQDt-gSARMKRLFDRFWSEkvilgaagv 160
gi 73667585   81 IPYylpfiaRIKIQDFDVIHIHEhRTLLAVIVHYyskkyNIPYVLQAHGTLPNTi-gKQNLKKIFDVLWGNkilkdaskl 159
gi 2621430    94 VPLklpyvaWREIREFDVVHIHEhRTFLAAVVATlasraGVPYIVQPHGSVPTMs--RATLKEVFDFIAGNrimygasri 171
gi 126180331  73 PSPslkawcRTHIGEYDVVHLNGaRSYQNSVVMSqatknDVPIVLQAHGSIMRIv-eRKGIKWLYDQVWGSrllasasaf 151
gi 153891177 127 LACsrelnaFLQSTPAAVIHHHGlWLRTLHYAHAaarrhGSTLIIAPRGMLEPWarnHHALRKKLASRFVHpgaieaaag 206
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                    ###                 
gi 5478236   150 -------------------kAPSLVIPNGVFLNEvevgdm-------dvpglpARRFILFLSRLHYKKRLDILADAYCRI 203
gi 84488886  150 iavs----keeaqydkqmkaHDVRVIYNGMNTKDyenlpedg----tykdkhiHSPYILYFGRLDKLKGIENIIKAFSLL 221
gi 119962757 153 fwltp-eertslvgllgdghGPLERLVNGVPPADaaag------------kegTSLEFLYLARLHRRKRPSVLVEAATLL 219
gi 118470651 153 ffld----svereqliavagPDLRLVELGNGVPEyptahs--------grtlgRAPEVLFAARMHARKRPVVFIEMAREL 220
gi 21227281  161 ialse--sevsqyekmgikkENVKIVSNGIKIDEfknlplrgt-frkkfsigvSDNLILYVGRIHESKGLDLVLRSFVNI 237
gi 126178628 161 ialne--teaeryrelgvadERIAIIPNGIDLAEypdlpvrgr-frtawgiddATKVVLYLGRLDPTKGIDLLIRSFAVV 237
gi 73667585  160 isvsn--tevdqylqmnvpiEKMVIIPNGIDVDSlsslpekgs--fraryhinQKHAILYLGRLHKIKGVDFLLRSFVEL 235
gi 2621430   172 vatstvesgfyrkvypkldaEAIVKVPNPVDIPHrpsrglf-----rkkwgleDARIILYLGRIHERKGLDILLRAFRDM 246
gi 126180331 152 ialsq--seadahrrlgvagEKVHVLPNGVDLERfkdlpgrge-frrkygiepDAKVVLYLGRLHKSKGIDLLVEAFADL 228
gi 153891177 207 whats--qaeavnfsdisggASVCVAPNGIHAPTtnaldqarrawlaacpvlaGKRVALFYGRFHPKKRVRELIQLWATK 284
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                        #                      #        
gi 5478236   204 aph-frdVDLVVAGPDGGAEDAfrrki-aeygLQHRVHMPGGLYgLAKIAALKrAACFCLPSRq--EGFSVAITEALAcG 279
gi 84488886  222 per-ydeYKLVIAGKSTPYKERlekii-etrnIEEKVIFTGFIKeEDKISIYHdADVFVNPVEy-mGGVAITVFESILaG 298
gi 119962757 220 aktidkpIEVAFVGPDEGEEPEvrrqi-rasgSSTWIRVEGPLKpSSTLERMRrASVYVLPSId--EPFPMSVLEAMSvG 296
gi 118470651 221 las-gmdARFTLVGPDEGEGPAira----algGDPRITWEGALSpEAIPARMAeADVYVLPSVr--EPFPMSVLEAMSvG 293
gi 21227281  238 lke-epnSKLVFLGPDNGFLNHlrllaktlclNDSAVIFTGFATkEEKIAALLdSDVFVTPTF---TGFPISFLEACFfG 313
gi 126178628 238 are-fddAVLMLVGGDMGHNDEfrqrv-eslgLDDRVVFTGFVSkEDKMAAYTdADVFVTPSF---TGFPVTFLEACLcG 312
gi 73667585  236 vkd-iddSVLILAGPDDGYKDKakeqi-refgLEKKVIFTGYMGpMDKISAYLdADILVYPSSf--EIFGLVPFEAIMsG 311
gi 2621430   247 de----dTVLVITGPDDHYLERlmgli-delgIGERVLLTGPLYeMDKLEAYVdADVFVLPSAskyESFGNSAAEAIAcG 321
gi 126180331 229 apr-iedARLVLVGPDGGFESDlqrqi-tdlgIEEKVRFTGLVPeREKYAAFIdSDVFVTPKF---YGFPITFAESCAcG 303
gi 153891177 285 ar---pgWTLLIAGIPEHYTIEtlrd--yagkIGAQHSVCIENG-LNRPPPYAiASLFVLPTHs--ENFGQTIVESLAaR 356
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
Feature 1                                                                                   
gi 5478236   280 APVVITDACHFPEVGEA-GAGVVCALNa-EMVGDALAGVLEd--lDKAAQMGASGAkl-vRENYTWPRIARQTIE 349
gi 84488886  299 TPVVVTKESGELIDIMNaGITVEYGNI--NQLKYAIIETIEnkplAKKHVLNGQAYi---HKNLKWTSVANKILK 368
gi 119962757 297 VPVVVTDSCGLAPFIAEsGAGIVCDSSv-EGLSAALRRFIEe---PGLLASTSAAAvglaREKFSMGGVTKQLED 367
gi 118470651 294 LPVVVTDDCGLAPIIEQcGCGAVTDPSv-SGLAAAVGAILRdrahTKSIGERGRETv---VERFGMRPVGDRLVS 364
gi 21227281  314 LPIVTTNKGDSLDWIHE-QVGYVVEYDs-NTFANATLTILKnkhlKDEFSIKAKNLv---ACEFSLDSFIKNIET 383
gi 126178628 313 TPIVTTGKGDLLGWIDN-SVGFNTGYTa-EALADAIGRLLAdetlRAGFGEQAKELv---RTRYNWQAIVSDIET 382
gi 73667585  312 TPVIVTDDCGCSEFIKRaSCGYLVKYGdvTDFKCKMRLMLEnpeiGNKFVENGQKYi---TNNLTWPLICKKMET 383
gi 2621430   322 TPVVVTSSCGISEWMDP-GDGIIARPSa-RDLRDAIIRVLKe---RDSFNPSAEKFd---PESISETFEDIYLEV 388
gi 126180331 304 LPIVTTNAGDYLDWIDG-VAGFSTAYSv-TEVSEAMARILSqdvrTSQFRENCRSLv---SEKFNWERICADLEV 373
gi 153891177 357 VPVLVTDTTPWHALNHE-RSGWCVSWD--DFPAALDRTLALp---PDALTETGDRGhsysITNYSWTATARRLLD 425

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