Conserved Protein Domain Family
GT2_BcE_like

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cd04183: GT2_BcE_like 
GT2_BcbE_like is likely involved in the biosynthesis of the polysaccharide capsule.
GT2_BcbE_like: The bcbE gene is one of the genes in the capsule biosynthetic locus of Pasteurella multocida. Its deducted product is likely involved in the biosynthesis of the polysaccharide capsule, which is found on surface of a wide range of bacteria. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.
Statistics
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PSSM-Id: 133026
View PSSM: cd04183
Aligned: 28 rows
Threshold Bit Score: 214.04
Threshold Setting Gi: 57167258
Created: 3-Jan-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Ligand binding
Feature 1:Ligand binding site
Evidence:
  • Comment:Predicted ligand binding site based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1           # #                                                                          
gi 28867934    4 IIVPMAGAGSRFAVAGYTDPKPLIPVHGVPMIKVVIDNLTpdc--phRFIFICQaeqvaayglrekln--awapgcgive 79
gi 72117851    4 IVITMAGRGSRFYAAGYKVPKYEIVAHDRSLFEWSMRSLKnflseesRIFFVCLaenrstdyvraecarlgiegvvefle 83
gi 110932065   6 ILFPMGGLGQRFRDQGYDLPKPLIAVDGEPMVLRALRSFDglv-gdlKIIFIVRqdaqtdhglaeslv--dyvpgatcvl 82
gi 90020072   10 VVITMAGQGSRFYKAGYTQPKYAIEAHGRTLFEWSMLSLKniinadsRLIFVCLqehnattfvkercl-algysdvhive 88
gi 160883767   6 IIMPMAGEGSRFLKEGWMVPKPLIQLHGDPLFIRAINSLDisd-iemKYSFIVRqehidkydidkmir--dylpvanvys 82
gi 123966635   5 LVIPMSGIGKRFKDAGYTTPKPLIKIRGKEIINHVVNMFGei----eRVIFICNeehlhdkklnlskilsnlhpkttvvs 80
gi 153010074   5 LVIPMSGQGSRFARVGYTDPKPLIKIDDHPMIEWVLRMFPge----eEPLFICRrehientamaqilt--dlrpngriav 78
gi 116058765  58 IIIPACGKGERFRAAGYDVAKPLIKVCGQPMIDCVVQALHtnd-aldEYVVIINfdandinh--------------pvik 122
gi 148323639   8 LIMPMAGGGTRFKNNKINIPKPLIEINDKPFFFWAAQSILkfv-eikSLIFVVLkehiekynidkkil--eyypnakiqi 84
gi 50954077  260 IVLPMAELGQRFRATSETQPKPLIEVDGGPMFRKALDSLTaag-irgDVTAIIRaelqrdhglgtalr--aaspdlrvve 336
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                       #                                                
gi 28867934   80 lggLTGGAACTVYAARhlin-ydqQVMIANSDQYVDVdinaylh------amnecdaAGLIMTmk-----asDPKWSFVG 147
gi 72117851   84 lntITDGQATSAYVCRdawe-qeaPLLIYNIDTYVNPralrptd-------iregsqGWVPCFka------pGDHWSFVK 149
gi 110932065  83 lagNTRGAVETCLVAAnlid-tdtPLVVMDCDLAFRSreyfsrlsr---fgspdggdGLLLSFps------qSPRYSYAQ 152
gi 90020072   89 iqaLTDGQATSALLSHhlwi-pntPLLIYNIDTYVQPsaltlsd-------mkpgsqGWVPCFqv------pGDHWSFVK 154
gi 160883767  83 vlkTTRGAVETCLLAEqgid-kddAIIVMDCDLEFRSlnfvaiikeilsktieevdgGALVSFqs------nMSKYSYAQ 155
gi 123966635  81 ikpHKKGPIHAVLEAEsile-slkPTIVNYCDFNSFFnfpnfinh-----lkkdqpdGCVFTYtgfhphmlkNTNYAYVK 154
gi 153010074  79 tegAKLGPVAALMAAAdeid-ndrPVLVSYCDYYMRWdydafka------amavddyLGAVPCyk-----gfHPHLLPVK 146
gi 116058765 123 ldrETAGAAETVLLALqahesgdvPMLLVDCDAIYHGdilerfra----leaqnvvrAAVLSFredasalssKPKYSYVK 198
gi 148323639  85 innILNGAVFTCLEGIklid-nddPILFNDCDHAFLSelfykycm----khnfsdidGALLTFys------dEERYSYIA 153
gi 50954077  337 laaPTGGAAETVLAAPldp---erPLLIMDCDIAFESpgyasela-----rataggaDGVLLSfp-----ssDPRYSFAA 403
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 28867934  148 FDSQghi------------nrvVEKEVISDEATVGIYNFRsggqLVSAIeam-vlKDLRVNGEFYVAPAYNELIEQGAKV 214
gi 72117851  150 LNDNgwa------------advVEKQRISENASVGLYWFAkagdYVTAYqdyyarPEHLVNGERYVAPLYRELLRRGGKI 217
gi 110932065 153 IDASgrv------------vdtAEKVVISQNALAGAYGFRsgrlFREYAerlvtrPLNSEMREYYLSFLFREMVGAGLTV 220
gi 90020072  155 LGEDgwa------------tdcAEKTRISDYASIGLYWFAcgeiYADAYqkffsdPANLVNGERYIAPLYKQLLADGKKV 222
gi 160883767 156 IDENnnv------------lrtAEKEVISNHALCGAYFFSkaegFLSAAyhl-lnEVNFSKSEFYVSLLYNYLLQKGETV 222
gi 123966635 155 KYKNsvvdi--------qekkpFTENPMNEEVSSGTYYFKsaklMLKYFkka-ilLDLKVNGEFYVSMAYKPMIKDGLKI 225
gi 153010074 147 NLYAscrvdaqgnlieirekysFEADKTKALHSPGIYYFHsgglMKKYCtrl-mdMGDSLNGEYYVSMVYNHLIRDGLRV 225
gi 116058765 199 VDEKsdv------------mqiAEKLRVGPLANTGAYWFAssaeFVRLAriv-ieEGRFQHGEAYVSCVIDEYLRQNKTV 265
gi 148323639 154 LDEKnnv------------ietMEKKVISNKAICGAYYFKnkdiFKTAVke---yLDNCIYDEYFISGLYNVMIKNNLLI 218
gi 50954077  404 TDDNgrv------------vrtAEKVAISRNALMGVYFFRrageFQECArevveaAQAGDVTESYLSLVYNRMLSRGSTV 471
                        250       260
                 ....*....|....*....|..
Feature 1                              
gi 28867934  215 IHYsigaeghGMYGLGIPVDLN 236
gi 72117851  218 SIVdlp--veDVHVLGTPAELD 237
gi 110932065 221 HLAka----dEYHSFGTPEELA 238
gi 90020072  223 SIAdlp--vtSVHVIGTPAELD 242
gi 160883767 223 QLAei----eEYYSYGTPEELG 240
gi 123966635 226 KTFli----nYFMQWGTPSDLE 243
gi 153010074 226 AVPeg---isHFCQWGTPEDLD 244
gi 116058765 266 RAViin--edEYSNIGTPDCLE 285
gi 148323639 219 KYFpt----dLHISFGTPEEYE 236
gi 50954077  472 RLAr-----gTFYCFGTPEELA 488

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