Conserved Protein Domain Family
GT_2_like_b

?
cd04185: GT_2_like_b 
Subfamily of Glycosyltransferase Family GT2 of unknown function.
GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
Statistics
?
PSSM-Id: 133028
View PSSM: cd04185
Aligned: 28 rows
Threshold Bit Score: 203.251
Threshold Setting Gi: 765062
Created: 16-Jun-2006
Updated: 17-Jan-2013
Structure
?
Aligned Rows:
 
Probable
Feature 1:Probable Catalytic site
Evidence:
  • Comment:Residues conserved among GT families of 2, 7, 13 and 43

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                          #                                             
gi 28377989    5 AIVVTFNRKQLLIESITALLNQTvp-paKIIIIDNHSTDGTKAELQTadilanp---------------------svdyr 62
gi 23464673   13 LIVTTYKRQQLLETLFDSILALEqa-pwRIVIVDNEQSDQTADMVAAfagkvtgqwgttva-------dqsgneervvya 84
gi 68643507    6 ALVVTYNRSKYLQKALEGILNQQqe-isGILIYNNNATDNTEEILMKfgyvdskgdkikeny----lystekdgkhfyyy 80
gi 765062      5 ALIVTFNRLDKLKKTVAETLKLDf---sTVMIVNNGSTDGTPAWLDSitdsr------------------------vvvl 57
gi 22726328    8 AVVVTYNRLDKLKVTLARLLESPaeelaQVVVVNNASTDGTADWLETqhdpr------------------------ltvl 63
gi 119715636   9 VVVVTYNRADLLAHMLDGLAAQTrp-adAIFVIDNASSDHTRALLTEqvaaarpg-------------------lplqvt 68
gi 124515944  15 VVLVTYNRKDLLLECLDGLLRQTrp-idGLVLIDNASTDGTADALYAqkflpevpplnarsvwefrreslregemtfvyl 93
gi 93211202   10 LVIVTYNRCNLLMEMLSSIENMSvk-pdIVYVIDNNSSDNTSSVVTEcdsrkni---------------------nikyh 67
gi 119351118   8 CIIVTYNRVSLLEKVLDGVLTQTfp-asKIIIIDNNSSDDTQIIIKQkksefk----------------------qieyy 64
gi 14578627    5 AVVVTYNRLALLKKVIDLLKRQTrq-ldSIVIVNNGSTDGTKEWLEQekni---------------------------tl 56
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                        ##                                              
gi 28377989   63 yLTKNIGGAGGFARGMqiaaadpnlDWASMSDDDAIFEPDYFEKLIayqqdhpnrQILTGSVYIEDGrlqadqrnrftnw 142
gi 23464673   85 pQTENLGGAGGFSVGVakay-elgaAWFWVMDDDVAVLPDAIAKLSkwt---dkhEVIQGSRFDYDGgpfywqydfivpl 160
gi 68643507   81 hNDENLGGAGGFANGIrlis-eldyDYVWIMDDDVYPEPNCLSEIMkqms-vqnvQVGIPNRTDENFddraiigfdfddy 158
gi 765062     58 nLPVNSGGAGGFKAGSqhicdaidtDWVFFYDDDAFPASDILEKFFalek--kecQVFTGLVKDLHGhpcamnlpfrkvp 135
gi 22726328   64 tSETNSGGAGGFAWGMrhavetcapDWLVVMDDDGRPAPGALAAFHalpe--dkwDAIAAAVYFPSGeicemnrpsrnpf 141
gi 119715636  69 hVEENLGGAGGFHLGVgmah-aaghDRIWLMDDDVVPAPDCLEILLah-----deACLMSVRQDTHGrlvekaalrfdlr 142
gi 124515944  94 rLPVNEGGSGGFHEGVkkal-efdcDWLWMMDDDVEPDEGCLQGQLafs---eisKCIHPRKYFQDGlahewegyisavt 169
gi 93211202   68 nTGYNAGGAGGFYIGSkmay-edgwDRIWLADDDIVLDKECLSNAMeyd---dgrTILQPMRYNMDGscaeisaiqydls 143
gi 119351118  65 nTGENLGGAGGFNYGFriae-khyyDFIWIMDDDLLPEKTCLEHLIlsa---dhdGIYQPLRFNLDGscaelspvvydls 140
gi 14578627   57 iNQSNSGGAGGFETGVkyay-eneaDWIWMMDDDVFPNIDCLEKLLgwt---sisQCIQPRRYYSDDvevnfeqwldpit 132
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 28377989  143 stfqa-------------qavpereyrgnfefdqyTFCGVFMSvavIKQVGVADAg-yFIWWDDCEYAVRTAKLSRpv-n 207
gi 23464673  161 gipnp-------------iapaafgpagyrvmdtlCFEGGLFNrrvVTEIGLPDPr-fFIYWDDTMYGYRASKVTNpi-v 225
gi 68643507  159 hkfwtem---------rktvtygpfdeeaikvvdmPFEGPVVEmalLRKVGIPDSg-fFIEYDDSDFAQRLQQYSDii-f 227
gi 765062    136 ssfadtlr------yirtpqrfvptidesvmvetvSFVGMIISskvLQEHIDHIHdelFIYFDDLYFGYALTLDGQkily 209
gi 22726328  142 wrlsefirtalgggrsgfhldpaeyqgqgtsidvtSFVGFFISaraIARIGYPDPs-lFIYGDDGIYTLGLTAAGGrigf 220
gi 119715636 143 nplsvrpkt----amveteygsrdlmpdrvelenvAFEGFMLRrevVDAIGLPDPs-yFIFYDDVDYAVRARRAGFhiwa 217
gi 124515944 170 grrvf------------qpdisfrkgfsfctintgCFEGMLIHrsvVEKIGLPDKr-fFLGGDDSVYGFLAHYHTPvl-y 235
gi 93211202  144 npfylrpk-------rktvqnifnknilsydiqsiPFEGPIIPrevFNVIGFPDEr-fFIFNDDLDFAIRAQRAGFsikc 215
gi 119351118 141 npfymnpkrl---tvlnyynnrhkdvhsafkihgvPFEGPLISkkvIDCIGFPNPd-fFIFYDDLDFSLRARKKGYt--- 213
gi 14578627  133 yskfgy-----------wqeksfnngkkfcainvgCFEGMFVSksiVNKIGFPDKr-fFIAEDDTIYGFAASFYTNvi-l 199
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
Feature 1                                                 
gi 28377989  208 vSAAKLIHKTalpsldfk----skfvpdwrLYYGQRNRLIT 244
gi 23464673  226 vPDVILRRTReignwdiagvrqlnstsdmnRYHIMRNRGYM 266
gi 68643507  228 aTKAQLHRQLavkvdpsev--kkvepynwrNYYKIRNNIIF 266
gi 765062    210 sPELIFHHDVsiqgki--------ispewkVYYLCRNLILA 242
gi 22726328  221 ePGVRFEHDLtsfqgegavq-rgrltplwkVYYYHRNLLIL 260
gi 119715636 218 vRDAVLVRQLpfdqqh--------dlsgwkGYFMYRNLFVV 250
gi 124515944 236 lRDPRINKKKiyqvenn-------pigdrsIYYGMRNTFLM 269
gi 93211202  216 iTNAKIVRKIpfvqsv--------alktwkGYFMFRNYFRV 248
gi 119351118 214 iECVPIARATrllynnqa-----ndldswkGYFMLRNLFYI 249
gi 14578627  200 vSDAIMVRARrssdrs---------vspmyTYYACRNFHLV 231

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap