1V67,1V3W


Conserved Protein Domain Family
LbH_FBP
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cd04650: LbH_FBP 
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Ferripyochelin Binding Protein (FBP): FBP is an outer membrane protein which plays a role in iron acquisition. It binds iron when it is complexed with pyochelin. It adopts the left-handed parallel beta-helix (LbH) structure, and contains imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes showing acyltransferase activity. Acyltransferase activity has not been observed in this group.
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Statistics
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PSSM-Id: 100055
Aligned: 4 rows
Threshold Bit Score: 253.261
Created: 21-Sep-2006
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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putative metalputative trimer
Conserved site includes 3 residues -Click on image for an interactive view with Cn3D
Feature 1:putative metal binding site [ion binding site]
Evidence:
  • Comment:Based on the active site/zinc binding site of Methanosarcina thermophila gamma carbonic anhydrase (1THJ).
  • Comment:Zinc ions are bound at the interface of neighboring subunits of the trimer. The trimer contains three zinc binding sites.
  • Citation:PMID 8665839
  • Structure:1V67_A; Pyrococcus Horikoshii Ferripyochelin Binding Protein binds zinc. The binding of zinc to only one subunit is shown in this structure.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                              #                #    #   
1V67_A        11 PRIHPSAFVDENAVVIGDVVLEEKTSVWPSAVLRGDIEQIYVGKYSNVQDNVSIHTshgYPTEIGEYVTIGHNAMVHGAK 90  Pyrococcus hori...
1V3W_A        11 PRIHPSAFVDENAVVIGDVVLEEKTSVWPSAVLRGDIEQIYVGKYSNVQDNVSIHTshgYPTEIGEYVTIGHNAMVHGAK 90  Pyrococcus hori...
YP_001191697  11 PRISPKVYLHPTSYVIGDVTIGELTSVWHYAVIRGDNDSISIGKRTNIQENCSLHTdkgYKIEIGDLVSVGHNAVVHGAR 90  Metallosphaera ...
NP_341912     11 PKVSQKAYIHPTSYIIGDVEIGDLTSIWHYVVIRGDNDSIRIGKESNVQENTTIHTdygYPVEIGDKVTIGHNAVIHGAK 90  Sulfolobus solf...

Feature 1                                                                                  
1V67_A        91 VGNyVIIGISSVILDGAKIGDHVIIGAGAVVPPNKEIPDYSLVLGVPGKVVRQLTEEEIEWTKKNAEIYVELAE 164 Pyrococcus horikoshii
1V3W_A        91 VGNyVIIGISSVILDGAKIGDHVIIGAGAVVPPNKEIPDYSLVLGVPGKVVRQLTEEEIEWTKKNAEIYVELAE 164 Pyrococcus horikoshii
YP_001191697  91 IGNnVIVGMGAILLNGAKIGDNVIIGAGAVVTEGKEIPSNSLVLGVPARVVRKLTEEEIHMIEANAMEYVEELL 164 Metallosphaera sedula...
NP_341912     91 VSShVIVGMGAILLNGSQVKEYSIIGAGSVVTQGTVIPPYSVAVGVPAKVIKKLREDEILIIDENAEEYLKHTR 164 Sulfolobus solfataric...

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