Conserved Protein Domain Family
HTH_MerR-trunc

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cd04762: HTH_MerR-trunc 
Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins
Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.
Statistics
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PSSM-Id: 133390
View PSSM: cd04762
Aligned: 37 rows
Threshold Bit Score: 54.5126
Threshold Setting Gi: 57641776
Created: 8-Nov-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
DNA binding
Feature 1:DNA binding residues [nucleic acid binding site]
Evidence:
  • Comment:Based on sequence similarity to BmrR and the structure of Bacillus subtilis BmrR bound to DNA (1EXI).

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
Feature 1         ###             #               ###             
gi 113941694  13 LSLSEASDLLGAAPSTVRRWGDAGLVpTKRTLgGHRRFQrAAVERMVNQ 61
gi 108763279  14 YTTHDISRLLQVDPSTVSKWIDRGILmAFRTPgGHRRVRsADLRTFLIT 62
gi 86159992    5 YTTFEAARLLGVSLPTVVNWIEARRLkAHRTPgGHRRIArEELAAFMLR 53
gi 21222116    4 YTIGQAARLLGVSPDTARRWADAGRVaTHRDEaGKRLIDgKDLAAFSVE 52
gi 54026298    4 LRVSEAAALLGVSDDTVRRWMDQGKLpAIQLDnGRKGVAgKDLAEFLRS 52
gi 71367274    3 YRIAEAAELLGVSDDTVRRWVEAGRL-ATRQQdGRSVVPgADLAALAES 50
gi 81366114    1 MKTKEMSEAIGVNPTTIQRWTKYFKIdCDVTEqGHFLYTeKHLQLFKKI 49
gi 89099093    3 MNTNKAASSLGVSPSTIQRWVKQFGLeVGRNElGHYHFEeDQLEILKDI 51
gi 16080756    1 MNTNMVASELGVSAKTVQRWVKQLNLpAERNElGHYSFTaEDVKVLKSV 49
gi 52082237    1 MNTADAANELGVSTKTVQRWVKQLQLpASRNElGHYFFTeDDIAILKEV 49

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