Conserved Protein Domain Family
Bromo_TBP7_like

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cd05491: Bromo_TBP7_like 
Bromodomain; TBP7_like subfamily, limited to fungi. TBP7, or TAT-binding protein homolog 7, is a yeast protein of unknown function that contains AAA-superfamily ATP-ase domains and a bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
Statistics
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PSSM-Id: 99923
View PSSM: cd05491
Aligned: 12 rows
Threshold Bit Score: 112.545
Threshold Setting Gi: 57226833
Created: 14-Sep-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative
Feature 1:putative acetyllysine binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                     #   
gi 50427609   978 YKRFRKPVVDEALlyhlfepti-------------------------------------lqnplnnyEVLYARSEDPdke 1020
gi 114196986 1118 YKRFRTGVIDESQirylweeddpni------------------------------vtsdlpiehrttFRPFEKALDKhgv 1167
gi 1729862    994 YKRFRKPPIDDAFlvhlfep-----------------------------------------etsndpNWQPAYIKDEn-- 1030
gi 111071055 1073 VKMLIQPIMDQLKksyrkfykpileeswyaylle------------eqdpehfgtdlapeqqqeqgvVRPWEFSKDSrgv 1140
gi 19114932   785 LKQTKQADMRLLNklkiklnallgslraryrkfkkp---------lidfndiycvdpetghsyrsreECHYEFVDDV--- 852
gi 85083472  1190 LKARLQPIMDQIQrryrkfrqpviplntisy------------------lfqesdpnfvrpdvgeqeQRPFVIAKDDkgv 1251
gi 2257509    957 YKKFKKPIIDLNDiyid----------------------------------------------esneRVVKGKSKDNfey 990
gi 88181645  1084 YRKFRQPVIPFAQiaylfdeadpn---------------------------------fvrpdivqteNRPYEIAKDKegt 1130
gi 57226833  1277 LSESSTGDIANISaapvs--------------------------------------------avnhlALPSASASTSa-- 1310
gi 116499514  892 LKFRLGPILSELKrkfkrftkrateeynfepdengigyvyqqvdvtagapatpngtatidltndamdTQPDGTAPEQqq- 970
gi 46125689  1123 LKIQLQPIMDQINrkykkfrqpvippaqiey------------------lfvesepnfvrpdieagqLRPYEIVKDKynn 1184
gi 154315268 1067 YRKFRTPVLQNSQfqylfdeqdp-----------------------------------nyvqpdipqFRPFELALDKkgh 1111
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
Feature 1                #  #                                      #   #     #               
gi 50427609  1021 ----nmIKEISTGKYYYNMDLDIVEERLWNGYYSEPKQFLKDIRMIVRDSITSGDr--ERILKANEMLTNAQFGI 1089
gi 114196986 1168 ----pgLRETVSGKFFYNMEIVTIEKRLSNGYYKRPKDFLADIKRLAKDARQLGDq--ERLLRANELLSNVEVDI 1236
gi 1729862   1031 -----mILEVSTGRKFFNMDLDIVEERLWNGYYSEPKQFLKDIELIYRDANTIGDr--ERVIKASEMFANAQMGI 1098
gi 111071055 1141 ----dvLLHVESGNKYYNLDLGNIEKRLSNGYYKRPKDFLFDIKTLVKDARTFGDa--ERTLKGNEMVTNVEVDI 1209
gi 19114932   853 ------VKQIGSDQKFSMMSLEEIEKRTWDNCYCTPKQFVHDIKLILRDALQLEDs--ETIKRAQEMYANVLLGV 919
gi 85083472  1252 ----dgILETKTGKFYYNLDSTTIEERLANGYYARPMDFYEDIKRLFLDVKTIGDk--DYLPKASEMVTNVEIDV 1320
gi 2257509    991 flsgntVTRKKDNACFKMMNFEEIERRLWSGRYCTPKEFLRDIKMIKQDAILSGDv--NLKHKAKEMFAHAELNV 1063
gi 88181645  1131 ----egIRETATGKFFYNLESTTIEERLANGYYARPIDFYKDINRLYLDAKNSGDr--DRTLKANELRTNVEVDV 1199
gi 57226833  1311 ------ALIPTPTWQAHNVDIDTIQRRLIRHKYYTPEDFLADIRKIEENAVKVGDp--ERQAKVVEMGANARLHI 1377
gi 116499514  971 ----atQQAMLQSPILYDMDLDKMHSELYKGRYLTPQHFLEDVRRIVHNAEVFQNedsDRFHKAQAMFTMAELSL 1041
gi 46125689  1185 ----dvLRDTASGKCYYNLETTTIEERLSNGFYARPKDFLFDIKALARDAKNIGDk--ERTLKANELLSNVEVDV 1253
gi 154315268 1112 ----kcLRETASGKIYYNLDTTTIEERLVNGFYARPKDFVFDIKTLVRDSKAIGDk--DRLLRAKEMLANVEVDL 1180

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