Conserved Protein Domain Family
Bromo_WSTF_like

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cd05505: Bromo_WSTF_like 
Bromodomain; Williams syndrome transcription factor-like subfamily (WSTF-like). The Williams-Beuren syndrome deletion transcript 9 is a putative transcriptional regulator. WSTF was found to play a role in vitamin D-mediated transcription as part of two chromatin remodeling complexes, WINAC and WICH. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.
Statistics
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PSSM-Id: 99937
View PSSM: cd05505
Aligned: 4 rows
Threshold Bit Score: 174.262
Threshold Setting Gi: 115952037
Created: 13-Sep-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative
Feature 1:putative acetyllysine binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                 #    #  #                                      #   #    
gi 18139836   947 EFQKCEEILAKLIKYRFSWPFREPFNADEIEDYTKVVTTPMDFQTMQSKCSCgSYQTVQEFLNDLKLVFGNTELYYEags 1026
gi 4165087   1344 ELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCgSYRSVQEFLTDMKQVFTNAEVYNCrgs 1423
gi 115952037  507 DKEAADGIISRMLKYRDSKPLRQPPTKAEVPNYKKLIKNPMDLQVMKTKCEGkDYSKYPEFFDDMQLTFSNAAKMYEndn 586
gi 122891371 1371 ELQKCEEILQKIMKFRHSWPFREPVSAEEAEDYQDVITSPMDLTTMQGKFKSsEYHSASDFIEDMKLIFSNAEEYNQpss 1450
                          90
                  ....*....|....*..
Feature 1          #               
gi 18139836  1027 SQLSCLEKTEQCARDLL 1043
gi 4165087   1424 HVLSCMVKTEQCLVALL 1440
gi 115952037  587 YILQQVRKTKDYCGNLI 603
gi 122891371 1451 NVLTCMSRTEEAFVELL 1467

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