Conserved Protein Domain Family
Ig2_RPTP_IIa_LAR_like

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cd05738: Ig2_RPTP_IIa_LAR_like 
Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
Ig2_RPTP_IIa_LAR_like: domain similar to the second immunoglobulin (Ig)-like domain found in the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR. LAR belongs to the RPTP type IIa subfamily. Members of this subfamily are cell adhesion molecule-like proteins involved in central nervous system (CNS) development. They have large extracellular portions, comprised of multiple Ig-like domains and two to nine fibronectin type III (FNIII) domains, and a cytoplasmic portion having two tandem phosphatase domains.
Statistics
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PSSM-Id: 319301
View PSSM: cd05738
Aligned: 5 rows
Threshold Bit Score: 139.029
Threshold Setting Gi: 115973321
Created: 17-Aug-2007
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226709091  152 ATMLCAAGGNPDPEISWFKDFLPvdpatsNGRIKQLRSGALQIesseeSDQGKYECVATNSAGTRYSAPANLYVR 226
gi 147901606  149 ATMLCAASGNPDPEITWFKDFLPvdtassNGRIKQLRSGALQIenseeSDQGKYECVATNSAGTRYSAPANLYVR 223
gi 134133283  154 TTMLCAASGNPDPEITWFKDFLPvdi-ngNGRIKQLRSGALQIenseeSDQGKYECVATNSAGTRYSAPANLYVR 227
gi 115973321   88 ATIYCGATGNPEPEILWFKEFVPie---aNDRISMTDSGLQFSra-qlSDQGRYECAAKNSLGTRYSVEAQVYVK 158
gi 125381302   70 ATMLCAASGNPDPEISWFKDFLPvdtatsNGRIKQLRSGALQIenseeSDQGKYECVATNSAGTRYSAPANLYVR 144
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