Conserved Protein Domain Family
Ig3_RPTP_IIa_LAR_like

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cd05739: Ig3_RPTP_IIa_LAR_like 
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
Ig3_RPTP_IIa_LAR_like: domain similar to the third immunoglobulin (Ig)-like domain found in the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR. LAR belongs to the RPTP type IIa subfamily. Members of this subfamily are cell adhesion molecule-like proteins involved in central nervous system (CNS) development. They have large extracellular portions, comprised of multiple Ig-like domains and two to nine fibronectin type III (FNIII) domains, and a cytoplasmic portion having two tandem phosphatase domains. Included in this group is Drosophila LAR (DLAR).
Statistics
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PSSM-Id: 143216
View PSSM: cd05739
Aligned: 6 rows
Threshold Bit Score: 123.46
Threshold Setting Gi: 115670863
Created: 7-Aug-2007
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 134133283  247 GGSVNLTCVAVGAPMPYVKWMTGevELTKDEEMPVGRNVLELTNirqSTNYTCVAISSLGMIEATAQVS 315
gi 157812     249 GSNLNLSCIAVGSPMPHVKWMKGseDLTPENEMPIGRNVLQLINiqeSANYTCIAASTLGQIDSVSVVK 317
gi 125381302  164 GGSVNLTCVAVGAPMPYVKWMAGveELTKEDEMPVGRNVLELNNimqSADYTCVAISSLGMIEATAQIT 232
gi 115670863  116 GGSVNLTCAAYGSPMPRVRWMKAgmDLDDMDDLPIGRNVLQLRDiyeSANYTCVATSLLGTIDTSARVT 184
gi 147901606  243 GGSVNLTCVAVGAPMPYVKWMAGleELTKEDEMPVGRNGLELTNikdSANYTCVAISSLGMIEAVAQIT 311
gi 226709091  246 GGSVNLTCVAVGAPMPYVKWMMGaeELTKEDEMPVGRNVLELSNvvrSANYTCVAISSLGMIEATAQVT 314
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