Conserved Protein Domain Family
Ig_Myotilin_C_like

?
cd05744: Ig_Myotilin_C_like 
Immunoglobulin (Ig)-like domain of myotilin, palladin, and myopalladin
Ig_Myotilin_like_C: immunoglobulin (Ig)-like domain in myotilin, palladin, and myopalladin. Myotilin, palladin, and myopalladin function as scaffolds that regulate actin organization. Myotilin and myopalladin are most abundant in skeletal and cardiac muscle; palladin is ubiquitously expressed in the organs of developing vertebrates and plays a key role in cellular morphogenesis. The three family members each interact with specific molecular partners: all three bind to alpha-actinin; in addition, palladin also binds to vasodilator-stimulated phosphoprotein (VASP) and ezrin, myotilin binds to filamin and actin, and myopalladin also binds to nebulin and cardiac ankyrin repeat protein (CARP).
Statistics
?
PSSM-Id: 319304
View PSSM: cd05744
Aligned: 3 rows
Threshold Bit Score: 161.237
Threshold Setting Gi: 5803106
Created: 17-Aug-2007
Updated: 18-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 5803106   366 VKLECQISAIPPPKLFWKRNNEMvqFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
gi 47214118  229 VSLECKVDASPTPQVFWKKDKEMlrIDPSRMSLYQDGCGRHRLLIEWVTKSDAGWYTVSAINVAGMSSCNARLDV 303
gi 93102361 1027 VRLECRVLGVPPPQIFWKKENESltHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap