Conserved Protein Domain Family
Ig2_KIRREL3-like

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cd05759: Ig2_KIRREL3-like 
Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2)
Ig2_KIRREL3-like: domain similar to the second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2). This protein has five Ig-like domains, one transmembrane domain, and a cytoplasmic tail. Included in this group is mammalian Kirrel (Neph1), Kirrel2 (Neph3), and Drosophila RST (irregular chiasm C-roughest) protein. These proteins contain multiple Ig domains, have properties of cell adhesion molecules, and are important in organ development.
Statistics
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PSSM-Id: 143236
View PSSM: cd05759
Aligned: 7 rows
Threshold Bit Score: 141.431
Threshold Setting Gi: 55735519
Created: 18-Sep-2007
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 150170691 135 PHNLTCRASga-kPAAEITWYRDGeimqnaiyskslMEDGKRETAVSMLPMVpedsDSGRTYTCRVLNPAAPAGRQTSVT 213
gi 148226710 139 PYNLTCLASva-kPAAEITWFRDGkkldwaiytkelLSDGKSEGSASSLLITpslaDTGSSYTCRVRNEALPEGREKSVT 217
gi 47215812  120 PLNLTCHADna-kPAASIIWIRNGevlngamysktlLRDGRRESTVSTLYLSpsniETGQQIICKASNKAVPNGKETSVT 198
gi 134085220 137 PYNMSCVSRga-kPASVIEWQKDGlpiegavsttevLPDRKRVTTRSYLPIQpldtDTGKNFTCVATNLAVPMGKRATIT 215
gi 54036152  138 PHNLTCRAFna-kPAATIIWFRDGtqqegavastelLKDGKRETTVSQLLINptdlDIGRVFTCRSMNEAIPSGKETSIE 216
gi 55792838  165 PLNLTCHADna-kPAASIIWLRKGevingatysktlLRDGKRESIVSTLFISpgdvENGQSIVCRATNKAIPGGKETSVT 243
gi 55735519  141 PANLTCRSRgdarPTPELLWFRDGvlldgatfhqtlLKEGTPGSVESTLTLTpfshDDGATFVCRARSQALPTGRDTAIT 220

                 ...
gi 150170691 214 INV 216
gi 148226710 218 LSV 220
gi 47215812  199 IDI 201
gi 134085220 216 LNV 218
gi 54036152  217 LDV 219
gi 55792838  244 IDI 246
gi 55735519  221 LSL 223
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