Conserved Protein Domain Family
Sortase_F

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cd05829: Sortase_F 
Sortase domain found in the class F family of sortases
Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.
Statistics
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PSSM-Id: 320678
View PSSM: cd05829
Aligned: 694 rows
Threshold Bit Score: 55.7038
Threshold Setting Gi: 486838834
Created: 23-Aug-2006
Updated: 18-Aug-2016
Structure
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Aligned Rows:
 
putative
Feature 1:putative catalytic site [active site]
Evidence:
  • Comment:The catalytic triad is formed by His, Cys, and Arg.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                           #            
gi 765674877  39 MAQPTRLSIAd-----lGIDATVLPMPagacpvl--dpptlaDAYWVGCRSEPgtd--sdGTVFVIGHAGag--taAVFD 107
gi 490738892  93 REGVEGMAISv-----dGETAPVDFVQvtdqgvl-lppqdvsRVGWYSASAIPgey--geGSSVITGHVNfagqgeGFAR 164
gi 697201916  71 RDGVNEMQLKi-----gGESAKVEFVQltdqgal-ippedvsKVGWYSASAVPgqegptvGTSVITGHVNeidqgdGFAA 144
gi 496377642  98 GDAPNRLILPd------GSAASVDTIAptgrgal-hpptdpgRVGWWVDSALPgs---gtGAVVVTGHINwa--ghAGFA 165
gi 765677817  54 DNPATPTQLRi------GSEAAVVLAIkttsggslippedvsKVGWWADSAFPgs---gtGTVVITGHINdvyagdGFGK 124
gi 933682103  50 HDPSTPKSVVi-----dGASAPTVSVAtdaagtl-lpptdiaKLGWWVDSALPgs---gaGTIVVAGHVDdlkqgtGYAA 120
gi 902721825  34 DEPAAPKSIEv------GGDSAVTDAVatdttgallppqdvhRLGWWVDSALPgs---gkGTIVVTGHVDeasqgrGFAA 104
gi 502891719  47 NESAAPVRVSa-----sGSDAPVDGVAtdaqgal-yppqdvgRVGWWIDSALPgs---grGSVVVTGHIDdarqgdGFAK 117
gi 494449480  51 DEKSAPKSIAv-----gGDSAITEAVAtdttgal-lppqdvrRLGWWVDSSLPgs---gkGTIVVTGHVNeadqgtGFAA 121
gi 491654975  96 PAQGSRGAVHememlidGKSAPIDFVQltdqgsl-ipptdvsRLGWYSASAIPgek-gaaGSSVITGHVNevdqgdGYAA 173
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                          #             
gi 765674877 108 TLPDIVa-------GSRVLIET-DSGTLEYTVRSTALYekfgeaqe----spelrlrqPGRLVLVTCYLeng--ttlSSK 173
gi 490738892 165 RFVDLAe-------GSEVIVHV-NGEDRAFRVSEPPEHvtkgdalp----evvnqaegDNRLVLITCGGefvggqlgYAD 232
gi 697201916 145 KFPELRp-------GDVVSVIV-DGEERQFTVSKDPIRvvkgaelp----esvnrstgENELVLITCGGefvggtlgYAD 212
gi 496377642 166 RRWLPPsaggrvepGQDITLSTtGSGPRRYRVTGTRAYdkrsglps-----evnrrtgPETLLLITCGGrwaggdlgYAD 240
gi 765677817 125 KFSALTp-------GSVVTLTGeDGHEWTYRIDAVDEYrkdgelpv----erlnrmdgPETLALITCGGefvgpplgYED 193
gi 933682103 121 RFAKLTa-------GDTVTVDTaDGAKHTYRVTRVVDAqkegkgadavpfdelnrldgPETLALVTCGGpfigpplgYRD 193
gi 902721825 105 RFSSLAp-------GTEVAVTTaKGETVHYRVRNVQKAdkekgfpa----aelnrldgPETLALVTCGGafvgpplgYAD 173
gi 502891719 118 RFGALRa-------GDTVSLTGkDGRTIAYRVTRTMSVgkgalpvg-----dlnrqdgPETLILVTCGGrfvgppmgYEN 185
gi 494449480 122 RFATMKp-------GETVAVTTaSGQQINYRVTRIQNAdketgfps----delnrvdgPETLALVTCGGqfvgpplgYKD 190
gi 491654975 174 RFADLKa-------GDTVTVKV-DGESRDFTVSKDPIQvvkgaqmp----eavndavgENRLVLITCGGefvggtlgYAD 241

                 ....*..
Feature 1        #      
gi 765674877 174 NFVAYAE 180
gi 490738892 233 NVITVAD 239
gi 697201916 213 NIVVEAT 219
gi 496377642 241 NLITTAQ 247
gi 765677817 194 NDIAWAT 200
gi 933682103 194 NIVVFAT 200
gi 902721825 174 NIIAWAT 180
gi 502891719 186 NDLVYAE 192
gi 494449480 191 NVIAWAT 197
gi 491654975 242 NIIVEAT 248

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