Conserved Protein Domain Family
Ig1_MRC-OX-2_like

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cd05846: Ig1_MRC-OX-2_like 
First immunoglobulin (Ig) domain of rat MRC OX-2 antigen (also known as CD200) and similar domains
Ig1_ MRC-OX-2_like: domain similar to the first immunoglobulin (Ig) domain of rat MRC OX-2 antigen (also known as CD200). MRC OX-2 is a membrane glycoprotein expressed in a variety of lymphoid and non-lymphoid cells in rats. It has a similar broad distribution pattern in humans. MRC OX-2 may regulate myeloid cell activity. The protein has an extracellular portion containing two Ig-like domains, a transmembrane portion, and a cytoplasmic portion.
Statistics
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PSSM-Id: 319317
View PSSM: cd05846
Aligned: 11 rows
Threshold Bit Score: 134.785
Threshold Setting Gi: 71896787
Created: 11-Jan-2008
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218512122  44 YTPASLKCSLqnaQEALIVTWQKKkavspeNMVTFSENHGVVIqpaykdkinitqlgLQNSTITFWNitLEDEGCYMCLF 123
gi 149432335  15 GGNVTLHCQLsqdKEVLQITWQKEsgrtseNIATASPSHGFRLmgrylnraslrtegWDSSALTLHSasLEDEGCYKCIF 94
gi 134085212 127 GKPVTFLCNYilsMRVRQVLWKKTaeqgdtAIVASYVKYSKPVvtspfkgrvslnpsLGQTRLSIHHaqTEDEGCYTCEY 206
gi 71896777   32 GNSVTLSCALtepKDIVQVTWQKDslksqsNIATYSKSTGLKIqkpyqnrmnltslmLNNTSITFWNarIDDTGCYLCLF 111
gi 74202089   38 GGNISIFCNFtslENVEQITWQKIqgslpqNIGTYSHKYGEKIlppyvnrlqckilePSTYFMTIQGvtFEDEACYKCLF 117
gi 61651788  127 GKQITLACRYglpEKVKQVLWKKIvtkaesREIAFFAKQSDPVieeefvervslspsLSDTQLTLWPvqSEDEACYTCEF 206
gi 71896787   43 GEEANFSCDFllpMDVFQVTWQKIngssfqNIVTYSQTRGLRLigsfrrkarfaraaLNTSVITLKNltFEDVSCYRCIF 122
gi 129300     44 HTTASLRCSLkttQEPLIVTWQKKkavgpeNMVTYSKAHGVVIqptykdrinitelgLLNTSITFWNttLDDEGCYMCLF 123
gi 149632483 162 GDSVILNCELrdlAEVLQVTWQKVqhslleNVGTYSRKYGVKIlpqferrfscnsseFMSSCLIIRDvtLEDEACYRCIF 241
gi 189540793  30 GQDASLSCTLpfvSGVRQVTWQRVraqdvhTLATFSERFKDNVdedfvrk-iifqasFNSTTIEIKNttFEDEACYICSF 108
gi 118083644  26 GGNITFSCQSvtnEDVIQVTWQKEmdgaedNIATYSTMNGEKIakaydghvsfahsgLEASSISLHRvtLQDEGCYKCIF 105
                         90
                 ....*....|....*.
gi 218512122 124 NTFGFGk-iSGTACLT 138
gi 149432335  95 NVFPSSp-vEGRMCLK 109
gi 134085212 207 HTYPDGi-kSTTACLS 221
gi 71896777  112 NTFPLGs-fSGRSCLG 126
gi 74202089  118 NTFPHGs-hGGQTCLT 132
gi 61651788  207 HTYPDVi-kSATSCLT 221
gi 71896787  123 SVYPHGsfsSKAMCLN 138
gi 129300    124 NMFGSGk-vSGTACLT 138
gi 149632483 242 NVFPDGy-hMGETCLI 256
gi 189540793 109 KVYPTGp-kRETLCVT 123
gi 118083644 106 NTFPSGa-vTGRMCLK 120
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