Conserved Protein Domain Family
Ig6_Contactin-4

?
cd05853: Ig6_Contactin-4 
Sixth immunoglobulin (Ig) domain of contactin-4
Ig6_Contactin-4: sixth Ig domain of the neural cell adhesion molecule contactin-4. Contactins are neural cell adhesion molecules, and are comprised of six Ig domains followed by four fibronectin type III (FnIII) domains anchored to the membrane by glycosylphosphatidylinositol. The different contactins show different expression patterns in the central nervous system. Highest expresson of contactin-4 is in testes, thyroid, small intestine, uterus and brain. Contactin-4 plays a role in the response of neuroblastoma cells to differentiating agents, such as retinoids. The contactin 4 gene is associated with cerebellar degeneration in spinocerebellar ataxia type 16.
Statistics
?
PSSM-Id: 143261
View PSSM: cd05853
Aligned: 3 rows
Threshold Bit Score: 174.416
Threshold Setting Gi: 119584280
Created: 11-Jan-2008
Updated: 18-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118097058  515 ESIVLPCQvsHDHSLDIVFTWSFNGhlidfekdgdhfervggqdsaGDLMIrsiqLKHAGKYVCMVQTSVDkLSAAADLI 594
gi 47940323   514 ESIVLPCQvsHDHSLDISFSWVFNGqlidfqkdgehfervggqdsaGDLMIrsiqLKHAGKYICLVHTSVDkLSAGADLI 593
gi 119584280  513 ESIVLPCQvtHDHSLDIVFTWSFNGhlidfdrdgdhfervggqdsaGDLMIrniqLKHAGKYVCMVQTSVDrLSAAADLI 592

                  ....*
gi 118097058  595 VRGPP 599
gi 47940323   594 VRGPP 598
gi 119584280  593 VRGPP 597
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap