Conserved Protein Domain Family
Ig_VEGFR-3

?
cd05863: Ig_VEGFR-3 
Immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 3 (VEGFR-3)
Ig_VEGFR-3: immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 3 (VEGFR-3). The VEGFRs have an extracellular component with seven Ig-like domains, a transmembrane segment, and an intracellular tyrosine kinase domain interrupted by a kinase-insert domain. VEGFRs bind VEGFs with high affinity at the Ig-like domains. VEGFR-3 (Flt-4) binds two members of the VEGF family (VEGF-C and -D) and is involved in tumor angiogenesis and growth.
Statistics
?
PSSM-Id: 143271
View PSSM: cd05863
Aligned: 3 rows
Threshold Bit Score: 125.822
Threshold Setting Gi: 82072489
Created: 11-Jan-2008
Updated: 18-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 82071567  361 VKLPVKvvaYPQPDFQWYKagkli-------pkqsqSSMQIkDVAEHHAGTYTLVLRNrlvgleKRISLQLIV 426
gi 1718189   352 VKLPVKlaaYPPPEFQWYKdgkals------grhspHALVLkEVTEASTGTYTLALWNsaaglrRNISLELVV 418
gi 82072489  373 VRLSVKvsaYPSPEIQWYKngklissknssrfkvqqHSLQIrDVCKQDAGEYMLVLKNspaaleKRLNFTLIV 445
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap