Conserved Protein Domain Family
Ig4_L1-CAM_like

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cd05867: Ig4_L1-CAM_like 
Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
Ig4_L1-CAM_like: fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM). L1 is comprised of an extracellular region having six Ig-like domains and five fibronectin type III domains, a transmembrane region and an intracellular domain. L1 is primarily expressed in the nervous system and is involved in its development and function. L1 is associated with an X-linked recessive disorder, X-linked hydrocephalus, MASA syndrome, or spastic paraplegia type 1, that involves abnormalities of axonal growth. This group also contains the chicken neuron-glia cell adhesion molecule, Ng-CAM.
Statistics
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PSSM-Id: 143275
View PSSM: cd05867
Aligned: 3 rows
Threshold Bit Score: 141.561
Threshold Setting Gi: 1171701
Created: 11-Jan-2008
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1171701  341 GETARLDCEvgGKPRPQIQWSINGVPieaagae-rrwlrgGALVLpelrpndsaVLQCEARNrhGPLLANAFLHVV 415
gi 1705571  347 GETARLDCQvqGRPQPEVTWRINGIPveelakdqkyriqrGALILsnvqpsdtmVTQCEARNrhGLLLANAYIYVV 422
gi 1305527  316 GETVRLDCQaeGIPTPNITWSMNGAPiagtdpdprrhvssGTLILtdvqisdtaVYHVEATNkhGNILINTHVHVV 391
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