1GXE


Conserved Protein Domain Family
Ig_C5_MyBP-C

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cd05894: Ig_C5_MyBP-C 
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C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
Ig_C5_MyBP_C: the C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C). MyBP_C consists of repeated domains, Ig and fibronectin type 3, and various linkers. Three isoforms of MYBP_C exist and are included in this group: cardiac(c), and fast and slow skeletal muscle (s) MyBP_C. cMYBP_C has insertions between and inside domains and an additional cardiac-specific Ig domain at the N-terminus. For cMYBP_C an interaction has been demonstrated between this C5 domain and the Ig C8 domain.
Statistics
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PSSM-Id: 143302
View PSSM: cd05894
Aligned: 5 rows
Threshold Bit Score: 134.206
Threshold Setting Gi: 33356956
Created: 11-Jan-2008
Updated: 18-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1GXE_A        24 IPDTIVVVAGNKLRLDVPISGDPAPTVIWQkaitqgnkaparpapdapedtgdsdewvfdkkllcetegrvRVETTKDRS 103
gi 212659    402 AENTIVVVAGNKVRLDVPISGEPAPTVTWKrgdqlft----------------------------ategrvHIDSQADLS 453
gi 61806596  515 SQNTIIVVAGNKLRLDVEITGEPAPTVCWMrddkpvt----------------------------dsegrvRVENKKDLS 566
gi 6093456   551 SENAIVVVAGNKLRLDVSITGEPPPVATWLkgdevft----------------------------ttegrtRIEKRVDCS 602
gi 6166597   531 ADNTVTVIAGNKLRLEIPISGEPPPKAMWSrgdkaim----------------------------egsgriRTESYPDSS 582
                         90       100       110
                 ....*....|....*....|....*....|....
1GXE_A       104 IFTVeGAEKEDEGVYTVTVKNpVGEDQVNLTVKV 137
gi 212659    454 SFVIeSAERSDEGRYCITVTNpVGEDSATLHVRV 487
gi 61806596  567 CFIIeGAEREDEGNYTITVTNpAGEDKANLFIKI 600
gi 6093456   603 SFVIeSAQREDEGRYTIKVTNpVGEDVASIFLQV 636
gi 6166597   583 TLVIdIAERDDSGVYHINLKNeAGEAHASIKVKV 616
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