Conserved Protein Domain Family
PurM-like1

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cd06061: PurM-like1 
AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.
Statistics
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PSSM-Id: 100037
View PSSM: cd06061
Aligned: 43 rows
Threshold Bit Score: 285.259
Threshold Setting Gi: 160878308
Created: 4-Jun-2007
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ATPdimerization
Feature 1:putative ATP binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 118726187   2 EPGKLPNDILNKIVFGKIntfrkevimrpg-----------------------igedcaaiefdkYACVMSTDPITaa-- 56
gi 160878308   2 KTGKVSEVILKRSVLKFLgtkqrntp-------------------------------visldagkIEFDESTDLLFatas 50
gi 154484060   2 NPGKVSEVTYKRAILKNLnsknegvkpg---------------------------vnaaniqledITAVVSSNCILkt-- 52
gi 163814595   1 MRGKFGEHQTVRSILKSLphtvhddvtragigedyarlllrdgdggentgktgdadcknagaaksKSVNVATGVCIds-- 78
gi 160893759   2 NKEKFRFIQQKRSILRSLnkqehsditqag-----------------------igddysrlvlldSELAVTEGLCLan-- 56
gi 57159220    3 PPGKLRNDILREVVFPNLgvedskvvygpre----------------------gfdsavleyddeHYLVVATDPTLgvp- 59
gi 15789478    2 DDGKAGRGFFDDHIAGRTgadrddvrlgpt-----------------------ygadfgvvaiadSVVAMATDPVFvlra 58
gi 126645914   3 DLGKINHEGYQSLLAGRLgafrkevkqgpgf----------------------gvdvaitslpggLAMAATSDPLSlips 60
gi 83589550    1 MIGKVDDAFFRQAILPHTgagdpevvvgpr-----------------------mgvdaavlkigeEYLAVAEDPIFpgpt 57
gi 51244349    6 LVGKPSPSRLQALVQGALgkpcksllvgpgp----------------------gldaailqtadgRVMAIAEDPIFpapg 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                          #                                             ###             
gi 118726187  57 ----gkNAGRLAVHISCNDIASSGVEPLGLMVTILCpvgttETELEHLMDQVCETAGQLNVEIIGGHTEVTPAVnk-iiL 131
gi 160878308  51 mqgnqfGLIESVFHRAVNNIYAKGGKPIAVSTSLTLrshadEQELKLYSKELNRLSTLYSIPVLSGETMVGAGAtq-ntI 129
gi 154484060  53 ----fdGCEEFYVQRSINSICEKGGVPKSLQLSITMplefeEKEVNRMIKNFRKSADSHNVEINQCNVYRGTTEgp--iI 126
gi 163814595  79 ----gyMGLRLDIARLYNSVRIGGYMPWVATDTIVMpd-ddERRMKKLLGKLAGICAECGVDIITGHTEVNTAVfe-piI 152
gi 160893759  57 ----alGTVTSDVIKQYNKLRLGGYQPFALTDTVMMpe-ndEKRMKKILRELSDLAKEFHMDVVYGDTAISGIFke-paV 130
gi 57159220   60 ----eeTFGFFTYHFASSDVAVFGARPRWLVVDLLFpegtsREFLEATMKDLNAECRKYGSAIVGGHTGVYPSIse-ptA 134
gi 15789478   59 --lgieRAAWFAFHICVSDVALSGLSPAHLAVDLNLppdtaTETFDAIWEVFDREARALGVSLTTGHTGTYEGCsfptvG 136
gi 126645914  61 --lglqESAWLSVHLMANDMATTGFAPQYGQFVLNLpdslsNADFSTYWGYIDRFCKEIGVAITGGHTGFVQGQnstfaG 138
gi 83589550   58 --tspdDFGWITVHIGASDVAVMGIKPRFMTYSLLLppgtpEDYIAGLVRSISTYARELGITIVGGHTGFYGAVtiptiG 135
gi 51244349   64 --lpldIMGWFTVHIGASDIAVTGVKPEFMTYTLLLplgcpEEDARTIISSISRAAEDLGISIVGGHTGWYGAVtvptvG 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 118726187 132 STTCVGKSLKDkiisss------gakpgDSVILTKSAGLEGTAIIAGDFEEElAEVMNKNELQYAKSLINAis-vVPEGV 204
gi 160878308 130 TIHATGKVNKQsntmdkkqesiedsakeYQIVMSKYIGLSATKLLIESRKEKlKERLTESFLAGGKKIGELls-iQKEME 208
gi 154484060 127 NIFMIGTTGNLlksds--------ikpgMDVIMAGTLAIGGTSVIAERYKDKlEGKFSGRFISECLELKDYts-tEKASA 197
gi 163814595 153 SVTMMGKQSGHsddadlc---rlkrpvgMDIVMCGQTGVGGTLQLYYDNQKElFERYSESYLRPVERMEELil-lGRQVD 228
gi 160893759 131 TVTMYGRRISQgekna-------kikpdMDIVMCGQAGILGTLLRVRERKEElLTRYSEEYLRTAEQFDRLl--lVKDQG 201
gi 57159220  135 TTTAMGIVRKGelklp-------lakpgDKIVVTAKVGLEFAVSAAYFRADElSKVLTKKELMRLKRSFYFet-aVPDAL 206
gi 15789478  137 GATALAVGAAEdvvtpt------gaqpgDRVVVTKGPAVETTGMLGVLFGDRlPISAAAAAAARDRFADATp---VRDAA 207
gi 126645914 139 GGTLITIAPESemicat------gaeegDVILVTKSCAMTATAILGMSFPETvKNKLGTDVYESACQQFYQts-sLKDGL 211
gi 83589550  136 GITVWGRGREVvtpag--------arvgDAVIITKGAAIEAAALVACELGEKlLAAGISPDLVARAKKRLRemsvVAEAG 207
gi 51244349  142 GVTVWGTADQDawispg------gakdgDLILMTKGPCIEAAALLSIVHHERlQGNISEEMLATLRARVDQit-vVEDAL 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 118726187 205 Lagrf-----gvtSMHDITEGGVLgaAWEIAeasSTGVTIKKDSIPVEPVTRHICDHFGINPLRLISSGCMIITCkd--g 277
gi 160878308 209 Vstdf-----dilCSHDVSEGGIFaaLWEVGeslQCGMEVSLDSILLIQETIEVCETLDLNPYLLYSGGCVLFVTkq--g 281
gi 154484060 198 Iaida-----gavYMHAVSEGGLFsgLWEVAscvDKGIQVDINKIPIWQQVIEIAEFMDINPYLLEGSGSLLIVSpd--g 270
gi 163814595 229 Ialeh-----gsvYAHDISRGGVFaaLWEMGdalKCGLEVCHDDIPILQETIEICEHTGDNPYMIDGCGAALFVVpd--g 301
gi 160893759 202 Diamac---gsiyVRHISTEGVYGa-LWELAeagNVGLRISHDHIPIMQETIEICEFTGDDPYRIDGCGAALFVTad--g 275
gi 57159220  207 Vakp------fvrGMHDATEGGLTa-LHEIAdnsGVGFRVYSDRLHIDPLVKKVLDFYDLKPWSVSSTGTLIAITptekv 279
gi 15789478  208 Tmaaa----gevtAMHDATERGLAngLHELAaasGVGLSVARDAVPVLPGVRAVCEQFGMDAWAASSEGTVIAAVdpgsv 283
gi 126645914 212 IaagesekfpeitAMHDVTEGGVLgaIYEMLiasGKGGMIENDLIPVGEIASQISKLFDLDPRYCVGAGAMIISCrpdks 291
gi 83589550  208 Iavev----ggvhAMHDATEGGLArgLWEVAeasGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCapeka 283
gi 51244349  215 Hafkv----ggvhAMHDATEGGVQggLWEMStssGLPVMVDFDGVEIPADIVALARELDFDPWQAISEGTLLAAVepeqv 290
                        330       340
                 ....*....|....*....|
Feature 1                            
gi 118726187 278 EGLVRLLgenniKASIIGTI 297
gi 160878308 282 EALVEKLnnegiPASVIGKT 301
gi 154484060 271 YKIEESLnangiYGEVIGKI 290
gi 163814595 302 EHLADKLyeagyEASVIGHL 321
gi 160893759 276 GLLSDRLyeagfEAAVIGRT 295
gi 57159220  280 NSLITELlkngiLAFELGEF 299
gi 15789478  284 DAVLGALgdegiPAADVGVV 303
gi 126645914 292 AQLIDRLgneniSCTVVGKV 311
gi 83589550  284 DAMLAAFkeagiEAAVIGRV 303
gi 51244349  291 QEVQRVWadlgiDSYILGKF 310

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