Conserved Protein Domain Family
FNR_like_1

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cd06196: FNR_like_1 
Ferredoxin reductase-like proteins catalyze electron transfer between an NAD(P)-binding domain of the alpha/beta class and a discrete (usually N-terminal) domain which varies in orientation with respect to the NAD(P) binding domain. The N-terminal region may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Ferredoxin is reduced in the final stage of photosystem I. The flavoprotein Ferredoxin-NADP+ reductase transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) which then transfers a hydride ion to convert NADP+ to NADPH.
Statistics
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PSSM-Id: 99793
View PSSM: cd06196
Aligned: 17 rows
Threshold Bit Score: 328.816
Threshold Setting Gi: 88804103
Created: 19-Feb-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Feature 1:FAD binding pocket [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                        #              ####             # # #       # ##
gi 77165070    3 YTVTLLMAEFVTHDVKRFIVSRPPGFdYQPGQGVELAINQPEWKDQGRPFTPTSLGEd-kVLEFTIKRYSD----HHGVT 77
gi 126730917   3 HTLTLQSISPVTRDTHHLVFDKPEGFaFTPGQAVDLSLDKDGWREEKRPFTFTSLPDe-dTLQFVIKSYPE----HDGVT 77
gi 84502858    3 HTLTLKRIEPVTHDTNHLWFDRPEGFeFRPGQAVELALDADGWRDEKRPFTFVSLPDe-eDLEFVIKSYPD----HDGVT 77
gi 114766594   3 RTLTLRSIAPVTHDTYRLTFDRPADLdYTPGQAAHMALDQEGWRDEIRSFTMTSLPGe-eQLEFVIKSYPEdaegHGGVT 81
gi 88813550   57 HTVTLLRSGCVTHDVLRLTTTRPEGFdCAPGQGVRLMLTKAGWEKKGRPFTPTSLQEd-gVLEFTIKIYED----HDGVT 131
gi 159046699   3 HKITLLETVELTPDTRHYVFTRPEGYgFTPGQATDFALDRYGWRDATRPFTFTGDPEa-dVLCFTIKTYAD----REGVT 77
gi 126734200   3 FSLTLQDIKPVTHDTYQLTFDRPDGFnFEVGQATHFALDQSGWRDEDRAFTMTSLPGdsdKLEFVIKSYPS----HDGVT 78
gi 85375124   21 HLLTLQSIRSVTHNVNELTFPKPDGFdFRPGQATDFALDRDGWRDEQHPFTFASLPAa-dHLQFVIKSYPS----HDGVT 95
gi 88804096    6 YHVQIKSISRLTHDTLCLRLSKPHGYrYGIGQAIEVAIDNPGYEQQFRPFTLTSLPFd-pYLELIVKVYPD----HGGFT 80
gi 118587641   2 HKATILKIDQVTHDVKRFRLVEPDGFdFKVGDATELAVDEDGWREETRPFTMTSLPEe-rTLEFTIKGYPD----HDGVT 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                           #                                            
gi 77165070   78 EKLHtlLPGE--ELLMSDPFGTITYQGTGVFIAGGAGITPFMAIIRQLsh-qDKLANHTLIFSNKTPaDIICEKEFRHYF 154
gi 126730917  78 EQIGklQAGD--KVLIEDPWGAIEDKGDGIFIAGGAGVTPFIAILRKKlqdkGTLEGNTLVFSNQTEaDIILKDEFDAMP 155
gi 84502858   78 ERIGrlTPGD--RVIIDEPWGAITDEGPGYFIAGGAGITPFVAVLRKRlaenGHLEDCTLIFSNETErDIILRRDFERMN 155
gi 114766594  82 ARIArlQPGD--TMLLEDIWGAIEDKGDGVFIAGGAGVTPFIAILRDKlarkGTLKGNTLVFSNKAErDIILRDSFEKMP 159
gi 88813550  132 RQIRslRPGD--TLQIGDPFGTILYQGPGVFIAGGAGITPFLAHLRTLat-eEKLDGHKLLFSNRTPnDVIEEHELRSYL 208
gi 159046699  78 DALWsaTPGD--GALIGDPWGAISDKGPGVFIAGGAGITPFLGILKARar-aGQLDGATLIFANGGPrDIIFRPLWDSLK 154
gi 126734200  79 ERIPalQPGA--QVIAEEPAGAITDHGPGTFIAGGAGITPFIAILRSHa--qKGAMDCHLIFANETEkDIILKDEFDAME 154
gi 85375124   96 EQIGqmQPGD--GVMIEDPWGAIEDRGPGTIIAGGAGITPFIAILRARqaehGDLEGYRLIFSNSEEkDIILRDELEKMP 173
gi 88804096   81 QALS--RLGEngPLIITAAWDSYDYRGEGVFIAAGSGITPFIPMIRQLsl-sGRIPGHTLLYANKTEaDIIHKQALNKAL 157
gi 118587641  77 ARLHklKEGD--TVLIDQPFKTFRYDEPGVFIAGGAGITPFLAIFRDLek-kGKLDGNQLIFANKTSdDIIYRQELEAMD 153
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
Feature 1                                                                            
gi 77165070  155 NEKCILTCTetsap--gyddQLITGEFLQqniaDFNQQFYTCGPPqfTKDINNALVELGANPNALVFE 220
gi 126730917 156 GLAVVYTVTdepds--gyarGQVDASFLKdlveVKGDVVYVCGPDgmVEALPREVAELGVPKDHVVTE 221
gi 84502858  156 GLTTVFTVTgdsdpgdgvetRRIDRQFLSeridPARGTYYICGPEpmIDDIETALRDLGVPEDRIVTE 223
gi 114766594 160 GLETCFLVTeeeds--plhrGQIDADLLGkhvtPGKDTCYICGPDamLDDIAEALTSIDVPEGDIVTE 225
gi 88813550  209 GDQCIFTCTresrp--gylnRRIDQAFLAehvsDFGQHFYVCGPRpfTREINEALQALGATPESLIFE 274
gi 159046699 155 GLKTVYAVSedga---gfayRRITGEMLEaeidDWDQRFYVCGPPpmEEDVVAMLTARGVPEDSIIRE 219
gi 126734200 155 GLKTSYLVSdqndt--dhtaGRPDKDMLSslvtDFDQTFYVCGPQkmVDAVRDALKELGASEDKIITE 220
gi 85375124  174 GLKLDLVLTdenvq--glhhGQIDGEFLEqvgvDFNGIVYLCGPPpmEEDLATALKARGVTDDRLVRE 239
gi 88804096  158 GSRFINILSreyhs--kldyGRLDQAYLKdkvsDFSEHFYICGPEafSGAIKGYLINQGAAEAQIQIG 223
gi 118587641 154 GLKVDHVLSdedta--gshhGMVDASMIKdlvpDLDRHFYLCGPPpmMDAVQEVLDNLGVKSNSVEFS 219

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