Conserved Protein Domain Family
PBP1_BmpA_like

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cd06304: PBP1_BmpA_like 
Click on image for an interactive view with Cn3D
Periplasmic binding component of a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria
Periplasmic binding component of a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. These outer membrane proteins include Med, a cell-surface localized protein regulating the competence transcription factor gene comK in Bacillus subtilis, and PnrA, a periplasmic purine nucleoside binding protein of an ATP-binding cassette (ABC) transport system in Treponema pallidum. All contain the type I periplasmic sugar-binding protein-like fold.
Statistics
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PSSM-Id: 107299
View PSSM: cd06304
Aligned: 193 rows
Threshold Bit Score: 184.25
Threshold Setting Gi: 15614364
Created: 24-Aug-2006
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
ligand binding
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1              ##        #                                                               
2FQW_A         6 VVGMVTDSgdiddksFNQQVWEGISRFAqe--nNAKCKYVTas-tdAEYVPSLSAFADe-NMGLVVACgsflveAVIETS 81
gi 16263875   31 KMGLLVPGsvs-eegWNRIGFNALKGVEae--lGAEVSYVElqqnpASFEKAFRDFASq-GYNVILGHgfefqdAALEVA 106
gi 134300602  41 KVALILPGkid-dvsWNQAMYEGVKALEkeyagKIEVTYTEqvyevSNIEPTLRDFASq-GYDLIIGHgfqfmePIIKVA 118
gi 160940451  89 KVALCLSGaan-dmgWCQSAYDGLKLLEad--yGCEVTYTEnl-tpDDIEAAFADYAAs-GYDVVIGHgyefgdPAVDVA 163
gi 14026430   58 SIAILTPEegt-dygWNQQGIDAAKAAGka--aGVEVVVAQgl-gyGDVRPTLRELASd-GASLLIAHasgyntSAPEIA 132
gi 118051750  13 RYAVVLFGpeg-qgsFNESGLRGAHKARe---aGHEVDVLWvagqsDQQRAAEMSALCggRYALILAHggqgdgPVQILA 88
gi 17134500   44 KIAIALPGait-dqaWNQSGYEGLNLAKqk--lNAEVAYVEqvaqaDQTEALTDFARK--GYNLVFAHggqfdaAIEQVA 118
gi 113477147  53 KIAIALPGvit-dggWNQSGYEGVKKAAek--lNAEMIYVEnvvqaDQTETISDFARK--GYNLVIGHggqfdaAIEQIA 127
gi 152981540  36 KIGILMPGskl-dhgWMESAYNGIKRAEarygsKVKISFIEnv-kfGDMEQVLVSLAS--KNDLVIGAagqtqaSVLKVA 111
gi 86136112   27 RAAIVMPGsis-dngWNQAGFEGLTQAGea--lGFETTFSEsvhqpEQIEVLSDYARR--GYDLVIGHggefqdAVERVA 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                   #                                                 #                  
2FQW_A        82 ARfpKQKFLVIDavvqdrdnvvSAVFGQNEGSFLVGVAAAlkakeagkSAVGFIVGmelgmMPLFEAGFEAGvkavd--p 159
gi 16263875  107 PEypDTVFLISSsyife-gnviGLNTDTSQPFYLMGVIAAkt-----gKKAGLVGGmeippIKEAFEGFTNGvrsva--p 178
gi 134300602 119 QEypETKFALGTgfktl-pntcVYDVKLEDGGYLMGTLAGlmt---ktNKIGVVGGadvaeIYRGHEAFKHAakqvn--p 192
gi 160940451 164 EQypDTKFIVTEgevsa-dnvaSYVSKCEEGGYIMGMLAAgms---esGKVGFIGPiqgasLVKIMNGFEDGakevn--p 237
gi 14026430  133 KElkVPVAIVDTpnglekglvaDYTLSGHQGAYLAGRLAAkms---rsKSVGIVVSgeppsWNSQSAAFAQGvkaenpdv 209
gi 118051750  89 DRwpEQAFAVTQgswta-anvaRYEVLQEQSAFLAGVLASqws---ktGKVGHFSGekvppGLRGRAAYADGlrrag--f 162
gi 17134500  119 PQfpNTFFVGVNgntka-eniaSLRIDHLQGSYLCGIIGAsvt---ksNKLAYIAGqeftaTQEELRGFELGaksvn--s 192
gi 113477147 128 SQfpGTFFLGVNgniag-enyaSVTTNYFQVGYLAGVVAGlmt---etNKVAYLTGlsfkgTNLQGRAFELGaksvn--s 201
gi 152981540 112 QRfpKVKFSIVGptgtptsnvaQYDVLQAQIGFIAGAVAAmss---knGAVSYVGGaeipaIVNTGKEFGNGaryvk--p 186
gi 86136112  102 SRfpETMFMVNNglgtk-envaNADFYFSQIAYLMGYIAGsmt---qsDTIGIIAAqkfkfTTDTVAGYEAGakaan--p 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                   #                                                     #              
2FQW_A       160 diqVVVEVANTFsDPQKGQALAAKLYDSGV-NVIFQvaggtGNGVIKEARDRrln-gqdVWVIGVDRDQYMDGvydgsks 237
gi 16263875  179 dfpVSEVYIGNFtDATATKEASLSLISQGA-DFVLPnasgaTVGGFQAAAESga----dVKTFSIFSDYTSVAp-----k 248
gi 134300602 193 diqIQELYTGDWrDAAKAKEGAISMYDAGA-DVIWHsgdgiGLGVVDAGKEKn------KTVLGNVADQNVLAp-----n 260
gi 160940451 238 diqVQTAWTGSFtDTALGKEAAQAMIDNGA-DVIGHcanesGTGAINAAKEAk------VYATGDSYDQNDLAp-----d 305
gi 14026430  210 kitYAVIGPAAYsDAAGGKRVTESVIASGA-DIIFGqgngsSFGMLQAVETTkaadggkVYFIDVIGDKSPIDk-----g 283
gi 118051750 163 egqLVTQFCGHQhRPGWARSCVSAMVEQTGlDIVFAmldggRPGVTQACRAQg------VAQIGNVLDWVARDp-----e 231
gi 17134500  193 niqIVSTFTGDWsDVAKAKEATLALISSGV-DVIYQwfdsaAPAVLQAASDKg------VYAFGNTKDQLDIAp-----k 260
gi 113477147 202 iveVVISYTGDFnDIAKGKEAALALISTGV-DVIYHlldnaAPAVLQTAQEQg------IYAVGNTTDQLDIAp-----k 269
gi 152981540 187 dikYFETYTGDFdDVTKAKEATLAAIGQGA-DVHYNilnlgVRGMEQAARDKn------TRMIGSYTNYCADKn-----p 254
gi 86136112  176 dvsVLVTWTGDWdDIAKGKEAALNQISQGA-DVVWPtmdsaTLGAMQAVQEKg------VYGIGIYRDAINEWp------ 242
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
Feature 1               #                                     
2FQW_A       238 VVLTSMVKRADVAAERISKMAYdgsf--pggQSIMFGLeDKAVGI 280
gi 16263875  249 NILGLYVADYARGVIRIVGDIRngkk--pttNVEFGLKdADVMKF 291
gi 134300602 261 NVLSGIAYNWTPVVKEMVDDILnnnftnrdkKFYWLTAaNGGVTV 305
gi 160940451 306 TILSSSVYHIPHVIEVAFKTVAdgt---fegGIYQLGMaDGAVSV 347
gi 14026430  284 FLLSSVVWNIEPVYAAMIADLKadt---fgtKHYTIGLkDDSVKL 325
gi 118051750 232 VFVASAICDSGEALFRAVEDHArgll-plggYRAFGLEePSLVRL 275
gi 17134500  261 AVLTSAVKRLDIAIAYLAEIAQqkq---lkgQIYTIGLeREDILF 302
gi 113477147 270 AVLTSAVQNVGEAIAYIANLAKnnq---lkgEKYILGIeNPEITK 311
gi 152981540 255 LYLAYTVSGIGFMLEYAIDQMVagt---wkpEYKPFGLaMGPQSA 296
gi 86136112  243 EILQSAILDVRGNMRSYLERAAase---ldgELYRATMsNELAMR 284

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