Conserved Protein Domain Family
PBP1_TorT-like

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cd06306: PBP1_TorT-like 
TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria
TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria. The Tor respiratory system is consists of three proteins (TorC, TorA, and TorD) and is induced in the presence of TMAO. The TMAO control is tightly regulated by three proteins: TorS, TorT, and TorR. Thus, the disruption of any of these proteins can abolish the Tor respiratory induction. TorT shares homology with the sugar-binding domain of the type I periplasmic binding proteins. The members of TorT-like family bind TMAO or related compounds and are predicted to be involved in signal transduction and/or substrate transport.
Statistics
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PSSM-Id: 107301
View PSSM: cd06306
Aligned: 16 rows
Threshold Bit Score: 348.523
Threshold Setting Gi: 153002396
Created: 26-Oct-2006
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                    #                                                                   
gi 2507361    46 KLCALYPslkdsYWLSLNYGMQEAArryGVDLKVLEAGGYsqlATQQAQIDQCKQw-GAEAILLGssttsfp----dlqk 120
gi 159044824  30 VLCVLVPhfkdeYWLSVGFGLEEEArkqNVELLFFEAGGYrarATQIAQLERCAAl-GVDAILIGavssdhpdltetlaq 108
gi 119774121  55 KLCVLVPhlkdaYWIGINYGLAAQAkklGVSFEMFEAGGYpnhDRQQTQLAHCLGg-DFDAVLLGavtphll----kdvp 129
gi 24372810   60 RLCVLVPhlkdaYWIGIDYGLIQHAkhlGVSLDLFEAGSYyhqDKQLAQLRSCMSg-DYDAILLGavspnll----ehfp 134
gi 71147126   54 KLCAVYPhlkdsYWLSINFGMTEQAkqrSIELKVLDAGGYqnkDEQLRQIEQCIHw-QASAILVGsvnfealn--qklaq 130
gi 153002396  55 RICALLPhgkdqYWWGVAFGLSQEAerqGVTLGIYDAGGYdkiEQQKQQLHDCYAl-KAQAYIIAantadglia-dieql 132
gi 85704580   47 TICVSYPhlkdaYWLSVNYGMVQEAerlGVGFRLVEAGGYpnlARQIEQITECVAq-GADALIVGtvsfdglt--ptvqa 123
gi 46912852   57 KICAVYPhlkdsYWLSINYGMVEQAkilGITLKVLEAGGYpelEKQKGQLQYCKKw-GADAIILGtvdrtayn--gilsq 133
gi 37676292   33 KLCAIYPhlkdsYWLSVNYGMVSEAekqKVNLRVLEAGGYpntAKQQQQLMLCSKw-GADAILLGtvdpmafn--enlqq 109
gi 150019297 118 TIGVLLPhfedqYWVSANYGIINYAkelGVKVKLYAVGGYiefGNQKEELMDLAEddKIDGIVFAtldntkfns-dveni 196
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                  #                                                                #    
gi 2507361   121 qvaSLPVIELVnaida------pqvksRVGVPWFQMGYQPGRYLVqwah------gkpLNVLLMPGpdnaggSKEMVEGF 188
gi 159044824 109 vsaDTPVFGLIneirs------dalsaRIGVDWTEMGHILGTFLRdrhps----gsepKTAVLLTGpaesgwTGPLEAGL 178
gi 119774121 130 gglNKPVLALVnkled------prvgtHIGVNWYQMGSLIGNAIKrqf-------tseASLALLAGpesvggTDLVEQGI 196
gi 24372810  135 lplSKPIIALVnklns------dqvltHIGVNWYQMGLRAGQFIKadakvh--tptqpTTLALLAGpenvggTDLVEQGI 206
gi 71147126  131 vnkHTPVFALVneiat------nnisgRTGVSWYQMGYQLGEYLVkhhqnn--fnttpATLAWFPGpkrgggSLQSTKGL 202
gi 153002396 133 saaGIPVIDLVngiat------dkltsRSLVSFEDMSVAATEYIAalqreainqespkLKVAWFPGpkgaswVMAAEQGF 206
gi 85704580  124 lseKVPVIAAVndiad------pgiaaKAAVSWYEMGATAGRFIAarhpk----gsapVRLAWFPGpegagwVGFVEAGF 193
gi 46912852  134 ftgDIPVFSMTndidmsdpeikmhikaKVGVDWYYMGKQAGVFLAqrhpk----gsgkMKVAWLPGpkqrggTKAVTTGF 209
gi 37676292  110 wtgSIPIFATVnqlvlnet-qsknlkgTVGVDWYWMGHQAGHYLAqkhpa----gsgtKNVVLLLGpkssggTKPVDKGF 184
gi 150019297 197 vhnDKPIVALVndins------pdisaKAIVSYYDMGYKAGEYVVedsa------gkdIKIAFFPGpkesgwASDTLNGF 264
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                   #    
gi 2507361   189 RAAiags-----pvriVDIALGDNDiEIQRNLLQEMLErhpeiDVVAGt-aIAAEAAMGEGRNLkt--pLTVVSFYLShq 260
gi 159044824 179 RDGlags-----tvtiLDIYRADTGlRQQLRLAEEALEhhpkvDYLIGs-aPAIEAAIGLFASHaapdrPQMLATYVSht 252
gi 119774121 197 GQSlsgs-----klsiGAIRHADNNrHLQREQLQQLLEss-rpDAIVGs-aVAIEVAVNQFGQTppsypIVLGASYFSpa 269
gi 24372810  207 RHAlegs-----nvsiSAIQHADNNrNLYRDQLQILLKaq-qpNYILGs-aVAIEAAVSTLKQKhmtqdIKLVSSYLSpa 279
gi 71147126  203 QAAlvns-----pieiIAIEHGLNEkITQFSLLKDTLKkynniDYLAGn-aVMAEMAINEVGRLpkeqqPEILSHYLShg 276
gi 153002396 207 RQAaakq-----afevIEGGYGTTElFVQADLVRKVLAkq-siDYVIAn-aVAATFAARFLDGRrn-qtGKVIAFYSNaq 278
gi 85704580  194 REAiaes-----sasiALTKYGDTGrEIQVTLIEETLDsgieiDYLVGs-aPTAEVAVSILRARglqdrISIVSDYMSha 267
gi 46912852  210 YDAlqds-----dievVSTLWADNSkELQRNLIQQLFTehpdiNYIVGg-aVAAEVAISELRTNhrtddVKIISTYLShg 283
gi 37676292  185 RDAikgs-----dihiMESFWADNDkELQRNLVQQAIDtp-dvDYLVGs-aVAMEAAISELRSAnktgqIGLISTYLShg 257
gi 150019297 265 KDAvsrlktndqkidiSNPFYGDTRpDVQRLHITSVLEnnddyDYLVGcapAVIEAEKFISKRKekfknIRIVSTYMTsd 344
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
Feature 1                       #                                   
gi 2507361   261 vyrglkrgRVIMAASDQMVWQGELAVEQAIRQLqgq----svSDNVSPPIL 307
gi 159044824 253 ikrslmngNVLAASFDDPMFQARLAMLAAVSEApg------qARVVGPEVR 297
gi 119774121 270 iaralqrgKIAAACDDKVVLQGMVAVELAVRQLqge----taFGDIGPAIV 316
gi 24372810  280 ilrglkrqKVLYSNDDLVVLQGKLAIDVAVKQLega----tpFGDIGPAIV 326
gi 71147126  277 vyrgikrhKILMANSDQMVLQGKMAINQAVDYLkig----kvKTLQAPTII 323
gi 153002396 279 tielvhkkQLLATVSDSPVLQARIAIDLAVRALega----pyPRRVSPVIK 325
gi 85704580  268 vfrgirrgRILAAPTDFPIMQGKLAIEMAVRAIegr----leQRHAGPKIQ 314
gi 46912852  284 vyrglrrgKILFSPTDKMAQQAQMSIDQAVRYLenk----pmEFDLAPKIQ 330
gi 37676292  258 iyrgllrnKIEFAPTDQMVLQGRLSVDQAVNYLrhk----pyQIHSSPTIE 304
gi 150019297 345 vfnlikkgAVLASPSDQTIQQCRIALDMIVRILngekagvdfPFQSGPCVP 395

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