Conserved Protein Domain Family
PBP1_uncharacterized_sugar_binding

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cd06307: PBP1_uncharacterized_sugar_binding 
Periplasmic sugar-binding domain of uncharacterized transport systems
Periplasmic sugar-binding domain of uncharacterized transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily. The members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes.
Statistics
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PSSM-Id: 107302
View PSSM: cd06307
Aligned: 60 rows
Threshold Bit Score: 222.039
Threshold Setting Gi: 121608816
Created: 6-Feb-2007
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                    #                                                                   
gi 84503508   60 RLDFVLpagsnsFMRTLKKNLLEESaa--rgDVTATLHEiegfdPERLSAKLIDLRh-RTDGVGLVALDHPQVreainal 136
gi 118472675  61 LIDVVMqtp-rrFSDAFRTAVEAELpafapaLLRARFHLwesgsTAQMVDTLARIK--SSHGVVLKAADEPEVveavdrl 137
gi 77968225   70 HVDVLLpdtdaaFFRRLQLALQRSLqml-drRVVVHRTIlpaadDERAATLIERPAy-RRAALIVTARDTARVrdalaga 147
gi 148261308  70 HLDLILpqndspFFVRLRAAFRDGIam--ldRGIAMHRHilaveDTASFVRLISETsyARKGMILAVPDRPEIraavqsi 147
gi 21225272   63 DIVMQApe---rFTTAVRAALEAELpalhpaVVRCRFHFretgpAGELTATLDRIArrGSQGVILKAPDVPEVtaavgrl 139
gi 162146178  61 TIDVLMeap-rrFTTEARAAFEAEMaafvplVFRCRFHLmetegPAALARAIDRIRlrGTDGMLVKVPDTPVIhaavara 139
gi 67156052   81 DVIMHTpr---rFSRIVEEAITAQVgsmapfRIRTRFHLfedidASRMYKLMLRCAanGSQGLILKAPDEPLLneavnrv 157
gi 121608816  57 DLVMEApt---rFSRMVRGALDEAMrrtqpaVFRARDHLaetrsAEQWVAVLDGIArrGSHGVLLKAPDLPVVadavarl 133
gi 15074778   63 DVVMEApe---rFTEAVRKAFESEAatfmptVFRSRFHFaetmrPQDISQLLDRIRlrGTDGVVLKAPDVPEIaaavarl 139
gi 84516691   63 DVIAEApl---rFCREIRIAAQSAAsampgvAVRLRFQLqetmtEAEILAALARIAkgGSNGICLKARDTPLLraaiadl 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                  #                                                    #                
gi 84503508  137 aasGVRIGTLVsdiptvdkvgYVGVDNRAAGRLAGLLLGrflppGQHRIAVFVGslayrgHEEREMGVRSIls-eeFPEI 215
gi 118472675 138 vaaGVPVVTYTtdvptsarcaYVGIDNHGAGATAAYLIEqwlgaDPADVLITLSrtvfrgEGEREVGFRSGl---rASGR 214
gi 77968225  148 iarGETVVTMVtdiggidrvhFAGIDNYRAGRTAGYYIGrl-aaRPGRVLLLGGrmgyraHADRMAGCRDQlaeafAAVR 226
gi 148261308 148 qaaGQKVVTIVtdlpglagadYLGIDNRQAGATAAHLLGrs-crQGGRVAVLGAhhdwagHVERMGGFQTTlsrdfPHLH 226
gi 21225272  140 tavGVPVVTLAtdlpasprvaYVGIDDRAAGATAAYLMGewlgdRPGNVLTSLSsgffrnEEEREMGFRGVmr-arHPGR 218
gi 162146178 140 aaaGITVVTFVtdlpsapraaYVGVDNRAAGETAAYLVGralgaQAATVLVTISssrfrgEGDREKGFRTVmr-acYPSI 218
gi 67156052  158 tqaGVPVVTLVtdlpqsqrigYVGMDNRTAGQTAAYLLAnwlddSPREVAVVISsdsfrgEEEREMGFRLWlr-nrMPHL 236
gi 121608816 134 qarRIPVVTLVtdmpsaprlsYVGLDNRCAGQTAAYLMDqwlgaHCCDVLVSSSgqrfqgEGERIEAFRVAla-aaRSDC 212
gi 15074778  140 enaGVAVVTLVtdlphssrtaYAGADNRAAGETAAYLIGerfadRPATVLVTISssrfrgEEEREIGFRRVlr-ekYPHI 218
gi 84516691  140 asaRIPVFTLVtdlpgsarhgYFGLDNAEAGRTAAHLLAqslpdDRATILTSRSqdafrgETDRFTAFRDLit-alKPAV 218
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                    #                   
gi 84503508  216 RIAGTAEVSDdrDRAYDETMRLLEhg-dISGIYNIGSGNQGIARALREARRdrkTVFIGHDLTdatrlmLLDRTMDAVID 294
gi 118472675 215 TVVEVTDSDGidATNERLVLQALErnpsVGAVYSPGGGNTATVAAFDRLGRh-cKVFIAHDLDvdnrrlLRDGRISAVLH 293
gi 77968225  227 CNDEPVETLDqdDRCYRAVTKALQahddVVAIYNSGAGSAGIEAALRKAGAagrVVWIGHEMIdlhrtfIEAGAMDLAID 306
gi 148261308 227 CEIIEMDTRDdpDRCARSLRAALSfg-pLVGVYNTGAGSIGIMNALKGAMPr--PFWIGHELSddhiiyLKDGTMDYAID 303
gi 21225272  219 ALVEIAEGQGldATQYDLVRAALErdpdIRAVYSMGGGNIATLRAFEDLGRp-cDVFVAHDLDqdntrlLRERRLSVVLH 297
gi 162146178 219 RVTSVCEGRGqdAETGRLVHDALAadptICAIYSIGGGNRATLDACREMGRa-iRIFVAHDLDadnralLAGHAIDFVLY 297
gi 67156052  237 SVRDISGGYGvyELTYERVKSVLQehpsLSAVYSVGGGNRAIVDAFAALERp-lQVFIGHDLDeenrrlLAEERVNAIID 315
gi 121608816 213 GVQVLDAGQGlhAPTVAAVGRLLTrqpwIAAVYSVGGANAAIRAAFEQAGRa-cRVFIGHDLDddnlalLRKRQLSAVLH 291
gi 15074778  219 GVVEISEGHGrnEETGALALKAIAshpeINAAYSIGGGNRAVLDAFGQLQRg-cVLFVAHDLDednldlLRQGLVQFVLH 297
gi 84516691  219 QIIDASGGAGmtASTSAQLDKILTsrvrIDGVYSMGGGNAAILRTVAAHGQq-pRVFVAHDLDrentqlLRRGAIGFVLH 297
                        250       260       270
                 ....*....|....*....|....*....|....*..
Feature 1        #                                    
gi 84503508  295 QNPRVEAREIVRLLAssvk--gtvePEYMPRLQVVFK 329
gi 118472675 294 NDLRADARLAMRLILqqhga-lpaePVRPAPIQVVTP 329
gi 77968225  307 QDPDGQVISALQHVLhacgiveqppPADPVEFRVFCP 343
gi 148261308 304 QNPRGQALGSLQTLLyrcglitstpALSHAELRIYTR 340
gi 21225272  298 HDLRQDLREACRHVMrahgalppagPARPSPIQVVTP 334
gi 162146178 298 HNLRADARAAFDVFRhgafc-rgesVARLSSVEIVTP 333
gi 67156052  316 HDLHADARHAFLHILqfhrv-wqsgPVPSSPIRIVTP 351
gi 121608816 292 HDLHHDLHLACHLLMqhhgaapsaaAPKRSNVEVITP 328
gi 15074778  298 HDLKTDVLMAFHAVLerrgalraseKRHLSAVEVITP 334
gi 84516691  298 HDLGRDMATLFAAAVggnkt-anqtASASSDLQIITP 333

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