2VK2


Conserved Protein Domain Family
PBP1_galactofuranose_YtfQ-like
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cd06309: PBP1_galactofuranose_YtfQ-like 
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periplasmic binding domain of ABC-type galactofuranose YtfQ-like transport systems
Periplasmic binding domain of ABC-type YtfQ-like transport systems. The YtfQ protein from Escherichia coli is up-regulated under glucose-limited conditions and shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their ligand specificity is not determined experimentally.
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Statistics
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PSSM-Id: 380532
Aligned: 38 rows
Threshold Bit Score: 271.785
Created: 25-Jan-2008
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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ligand binding
Conserved site includes 12 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:2VK2; Escherichia coli galactofuranose-binding protein binds beta-D- galactofuranose, contacts at 4A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1              ## ##                                                                  
2VK2_A      4 TVGFSQvgsESGWRAAETNVAKSEAekrGITLKIADgqq-kqENQIKAVRSFVAqGVDAIFIAPVVATGWEPVLKEAKDa 82  Escherichia coli K-12
CBL24492   50 RVGLSItdsNYQWINDQISTFEKAAsdnNMVLVYHNidqpdsQKQINDINTLISqDVSYLIIMPVDDSVLDVVFNIEKIk 129 Ruminococcus obeum...
OXR48210   32 RVGISSpesQNPFHVVMARSIAETLkarGIEPMLLAana-dvNQQINNIGDMVAaKVDAILVAPLNAEGPAAALVKAKDa 110 Pusillimonas sp. T2
YP_888452  93 KITFSVeglSHPFLVKQKQLAEETGkrlGAQVNVISand-dvNQQFNDIQTAIAqGTDALMMMPATTQGLDAVLKQAEAa 171 Mycobacterium smeg...
OJY41914   29 TVGISLpeaQNPFYVLLGKSAVETFkqrGIEATLLSana-dvNEQINNINDLAAkKVDAILMSPLDTEGPASAVKRAHDa 107 Rhizobiales bacter...
OGP28655   30 VIGVSLassTNPFYVAMEKGMLEKAqelGVTLRLVRaee-dqVKQLDGVMDLIQsRVDVILISPITAAGAAPAYEAARSa 108 Deltaproteobacteri...
ENZ16316   58 KVGISYaevSAGFNVSQAEAFEKIGkdyGYQVTLLNadn-nvEKQVADVEDLIAqGMDVIFFNPVDSSACSTVMDKVKAa 136 [Clostridium] clos...
CCX98592   39 RVGLSQaepLTPWKTAQIKSFKEAArrrGAQLIYHApeeeslEWQIEDIYGLLDaGIDYLILIPSARNGYDQVLLEARQr 118 Clostridium boltea...
AMN45313   31 TIGVSLaqdDNPFYIAMLRGIRARAqelGWEVATVSane-dkVKQINGVQDLVAgGVKGILISPIDAVGVNAAYDAAKAg 109 Rhodoplanes sp. Z2...
OFZ87722   27 VVGLSLasdTNPFYIVMRNGVEARAkelGWEVRVVTane-dvNKQVNGVLDLVAqKVDGILISPIDAVATGAAYEAAHKa 105 Betaproteobacteria...

Feature 1              ##                                                       #   #         
2VK2_A     83 --EIPVFLLDRsidvk----dkslYMTTVTADNILEGKLIGDWLVkevn-gkpCNVVELQGTVGASVAIDRKKGFAEAik 155 Escherichia coli K-12
CBL24492  130 sgDLPLIVIADqipd------tapYVFFIQTNYREEGQTCAQIISdtya-gksCNLIEIKGPANSYIATKRYQGFHDEir 202 Ruminococcus obeum...
OXR48210  111 --GIPVFMYARtldsk----yadvWESFNGMDAVHVGRDKARWMAent---kpGKVAMLTGMAGAAPMIEQETGFREVit 181 Pusillimonas sp. T2
YP_888452 172 --QIPYFFSQKgml-------gvePASQVLAPYSNEGQQLGEWVVehykgqedVKVAIISGIPGDQSSDARVNSFLLPll 242 Mycobacterium smeg...
OJY41914  108 --GIPIFMVARtldkr----fgniWKTFVGIHFDEIGKSKGEWVVknt---kpGKVAMLLGPAGALVMVEQDKAFRSVie 178 Rhizobiales bacter...
OGP28655  109 --RIPVLSVARsvd-------akyHVAFVGTDWTKQGERIGEWLAgkl--rsgGKVGMLLGPAGASVSIDMENGFRRGvg 177 Deltaproteobacteri...
ENZ16316  137 --GIDMVVFNAkadgy---epgtdYLFLGIGECYDQGAEVARWVSqnyknegtMRILHLTGSMSQSWSLDRGQGFVETie 211 [Clostridium] clos...
CCX98592  119 --GVPVILAEQdvemepeydredyILGYVASDYYAEGELCADILArhfg-iepCHTMVIQGEKSSAMDWERYMGFMHGvr 195 Clostridium boltea...
AMN45313  110 --NVPIVSVARgst-------spnQTLHVAMDEKQIGRDIAEWTAkai--gdeGKVAMLLGPSGAPTFRNLGDGYAEMma 178 Rhodoplanes sp. Z2...
OFZ87722  106 --NIPIISIARgak-------sayQTLFVAMDSVQIGRDVAAWAAqta--rgkGKVGMIAGPAGANVFEELAQGFKEQma 174 Betaproteobacteria...

Feature 1                    #                            #                           #       
2VK2_A    156 -naPNIKIIRSQSGDFtrSKGKEVMESFIKaenngkniCMVYAHNDDMVIGAIQAIKEAglkpgkdILTGSIDGVpDIYK 234 Escherichia coli K-12
CBL24492  203 -kySNMHIEATVSSDFnrQTAQDAMERLIAsets-pkiDAIFSCSDEDGLGVLNALNLSgyfdhsdVTLVSIDGTqDILM 280 Ruminococcus obeum...
OXR48210  182 --aAGYQIAFSQTSNMtrEYGIKLTEDALVtnp---dlVGIYAANDDLALGAAQAVKVAglq--gkVVVIGLNGApSALA 254 Pusillimonas sp. T2
YP_888452 243 -rsCNFNVVANQPGNYrrGDSEKAAQNMLAanp---diDLLFGANDEAALGGIAALKSSgr---qgVDVVGLDGQtDMFA 315 Mycobacterium smeg...
OJY41914  179 --pAGYKVTFAQNSTQtrENGLKLSEDALIanp---dlVAIYASNDDLALGAAQAVKAAgkt--gqVAVIGLNGSpPALA 251 Rhizobiales bacter...
OGP28655  178 -khGGIRIVAAHHSALtkADGLKLAEDILIavp---dvQAIYAMNDELALGAVQAVKAAkm----rVVVTGFNGVsPAIS 249 Deltaproteobacteri...
ENZ16316  212 aerPDHEFVSTQCANCsrIDAQQMTLNVLQatq--ggvDVIYAHNDEMILGAIAAVKEFglepgkdVMTCGIDLSmEMCE 289 [Clostridium] clos...
CCX98592  196 -ehSNLYVSKRVESSGnrLTAQKVTESVIAdqd--idfNAVFAQSDEDGLGVLQALKLAgmepgedVVIVSIGGIqDVFK 272 Clostridium boltea...
AMN45313  179 -khPKIQIVSKSDGPLtrERGVKQAEDALVahp---dlKAIYTANDDVALGAMQAVLAAgk----sTLVTGMNGVpPALR 250 Rhodoplanes sp. Z2...
OFZ87722  175 -knKDMPIVFEHHVALtrEQGLKQAEDLLVahp---dvRVIYAGNDELALGAAQAVAAAgkk--sgVLITGLNGIpPALA 248 Betaproteobacteria...

Feature 1                 #                                             
2VK2_A    235 AMMdGEANASVELTp-NMAGPAFDALEKYKKDgtmpeKLTLTKSTLYLpdtaKEELEK 291 Escherichia coli K-12
CBL24492  281 AITaGEYKATVQSSp-RLGYAAFDLIAQLERGyd-gtHRILLPYRIYDsdnaLTYLTN 336 Ruminococcus obeum A2-162
OXR48210  255 AIHnGDLTATVLLDpvGWGKTAANVVADYLLEgkkpaKFTPMDHKVVTqkeaYDNIPP 312 Pusillimonas sp. T2
YP_888452 316 AIQsGQALATVIHKp-TAGIVVEEAVDYLRGKpv--pEYRVLDEDLVTketiETGAQP 370 Mycobacterium smegmatis str. MC2 155
OJY41914  252 AVHkGEMAATVLLDpiGWGRTAALTVADYLQNkkepePFVTFQYRMVGqadaFDLIPP 309 Rhizobiales bacterium 64-17
OGP28655  250 AVKaGDLGMTIALKpmTWGKLAVQAAVGHANGks-lpRIVEIETVLVDqsnvARLTPQ 306 Deltaproteobacteria bacterium GWA2_57_13
ENZ16316  290 SILdGELSSCLIIDpeAIVYGLYDNYTKYLEGed-ypKITGLKLRMCDpgnaQDELDS 346 [Clostridium] clostridioforme 90A7
CCX98592  273 AIIaREYLATVKSSp-EYGDAVFDIINRHQRGed-pdRQTMVKHREYTmdnaEELFED 328 Clostridium bolteae CAG:59
AMN45313  251 AVKdGKMAMTIELNpvLWGRLGVDVLATYLKGdk-vaPQVFIKHVIIDktnvDEKLPK 307 Rhodoplanes sp. Z2-YC6860
OFZ87722  249 SVTkGDMDLTVVLSpmAWGRLGVDVMANWMKGer-pkQHVFIKHILATkenaAKYMPP 305 Betaproteobacteria bacterium RBG_16_64_18

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