Conserved Protein Domain Family
PBP1_YtfQ_like

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cd06309: PBP1_YtfQ_like 
Periplasmic binding domain of ABC-type YtfQ-like transport systems
Periplasmic binding domain of ABC-type YtfQ-like transport systems. The YtfQ protein from Escherichia coli is up-regulated under glucose-limited conditions and shares homology with a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their ligand specificity is not determined experimentally.
Statistics
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PSSM-Id: 107304
View PSSM: cd06309
Aligned: 31 rows
Threshold Bit Score: 337.67
Threshold Setting Gi: 32700053
Created: 25-Jan-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                     #                                                                  
gi 732294     25 TVGFSQvgs-esgWRAAETNVAKSEAek-rGITLKIADgqqkqENQIKAVRSFVAqGVDAIFIAPVVATGWEPVLkeAKD 102
gi 160938714  72 KVGFSElai-dgaWRVAQVDSMQKEAes-rGYEFVMSNaeldtAKQISDVEDLLTqDLDFLFIAPIDMEAIMPAIeaAKA 149
gi 78063218   55 VVGFSQseneqnpFRATETASVRAAAkaagVKRLLYTNananqAKQVADIESMINqGAQALIVAPNDSTGLQPALaqARA 134
gi 29827512   86 TVGFSQsekeanpFRIAETASLKAEAgk-rGVKLLTANaqsqfSKQISDVQDLIAkGADLLVIAPLNSDGWEPVLrqAAA 164
gi 16264669   40 KVGFAQtes-nnpWRIAQTNSMKAEAek-lGHQLVYTDaagsaAKQVADVNSMIAqGVDLIFLAPREEKPLIPAVmaAKK 117
gi 121608989  33 KVGFAQtes-nnpWRIAESKSMQDVAkt-cGWNLVYTDaagsaAKQVADVESMIAqKVDLIVLAPREEKPLIPAVrkAKK 110
gi 160939590  90 LIGYSQlan-tgtYRIAETNSMKDEAek-rGFKLIVTDaqdntAKQVSDVEDLIAqNIDLLILSPREFEGLETALqtAKE 167
gi 77971103   55 VVGFSQseneqnpFRATETASVRAAAkaagVKRLLYTNananqAKQVADIESMINqGAQALIVAPNDSTGLQPALaqARA 134
gi 50952198    1 MVGFSQsekednpFRITETASIEEAAakagVKKFIKTNaqstlAKQISDIQDLIAqSADVLIVTPLNSDGLEPALqaART 80
gi 50955716    1 MVGFSQsekednpFRITETASIEEAAakagVKKFIKTNaqstlAKQISDIQDLIAqSADVLIVTPLNSDGLEPALqaART 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                #                                                          #            
gi 732294    103 AEIPVFLLDrsidv---kdkslYMTTVTADNILEGKLIGDWLVkevngkpCNVVELQGTVGASVAIDRKKGFAEAik-na 178
gi 160938714 150 KGVPTILLDreang---tpgvdYICTILSNYIWQGEACADWLSenggadsYKIVQITGKVGGSDVRDRQAGFETGvk-ky 225
gi 78063218  135 KGIPVVTIDrqtag---tpcqdFITFLGSDFFRQGQRAAQALAdat-ggkATIAEIQGGYGNTVESQRTDGFADGlk-kf 209
gi 29827512  165 KKIPIVTVDrkina---tpctdYVSFIGSDFTEQGKRAADEMIkat-ggkGEVAILLGAAGNNVTTERTKGFEDRlqeka 240
gi 16264669  118 AGIPVILLDrsvdpslakagedYVTFIGSDFIEEGKRIAEWLVkna-ngkSKIIELEGTTGSSPANDRKKGFDETik-aa 195
gi 121608989 111 AGIPVILIDrdvdpklakvgvdYVTFIGSDFVDQGRRAAEWLVkas-kgqGKIVELEGSTGSSPANNRKKGFDDVia-kn 188
gi 160939590 168 NSVPVILVDrlakg---eagvdYVTYIATDFVWEGQAAGEWLKdkt-ggtCNIIELTGTVGSSSAQDRATGFAGVvd-qn 242
gi 77971103  135 KGIPVVTIDrqtag---tpcqdFITFLGSDFFRQGQRAAQALAdat-ggkATIAEIQGGYGNTVESQRTDGFADGlk-kf 209
gi 50952198   81 KNIPVITVDrklna---kacsdYVSFLCSDFVEQGRRAADQLIagt-ggkGDIAILLGACGNGVTIDRTKGFVDQikakg 156
gi 50955716   81 KNIPVITVDrklna---kacsdYVSFLCSDFVEQGRRAADQLIagt-ggkGDIAILLGACGNGVTIDRTKGFVDQikakg 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                             #          
gi 732294    179 PNIKIIRSQSGDFtrSKGKEVMESFIKaenngkniCMVYAHNDDMVIGAIQAIKEAglkpgkdILTGSIDGVpdiykamm 258
gi 160938714 226 ENMEIVATQSGEWsrTEAQKVMQNIIQstg--gdfNVVYCHNDEMALGVVLALKAAgmnpgtdVKVIAIDGQaeaveaii 303
gi 78063218  210 PNMKIVASQTANWsaTEAQKVMEQVLLahp---dvTAVYAQADTMALGAMTALRQAgkq--rgVTVVSIDGTkdfvtaia 284
gi 29827512  241 PGLKIVFRQTGEFarEKGQSVTENLIQskp---giTGVYAENDEMGLGAVNALKSAgkk-pgdVKIVTVDGTrnavqgiv 316
gi 16264669  196 GGFEIVASQSGDFarDKGRQVAEALLQahp---daDIVYAHNDEMAIGAIAAIEAAgkvpgkdVLVLSIDGGkeavqavi 272
gi 121608989 189 TGLKIVASQSGDFsrDKGRQVMQTLLQahp---dvTAVYAHNDEMAIGAISALEAAgkkpgqdVVVVSIDGTrdaltaia 265
gi 160939590 243 EGMKIIASQTGNFerSEGQKVMENLLQahg--gevDAVFCHNDQMALGAVQAIKAAgykpnedILVIGIDGEmdsfksvi 320
gi 77971103  210 PNMKIVASQTANWsaTEAQKVMEQVLLahp---dvTAVYAQADTMALGAMTALRQAgkq--rgVTVVSIDGTkdfvtaia 284
gi 50952198  157 PGLTIVAQQTGDFarDKGQSVTEQLLQahp---giTAIYAENNEMGLGAQAAIIAAgktpgkdIQIYSIDGTrnaveqia 233
gi 50955716  157 PGLTIVAQQTGDFarDKGQSVTEQLLQahp---giTAIYAENNEMGLGAQAAIIAAgktpgkdIQIYSIDGTrnaveqia 233
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
Feature 1                 #                                 
gi 732294    259 dGEANASVELTpNMAGPAFDALEKYKKDgtmpeKLTLTKSTLY 301
gi 160938714 304 aGEMNCIATCNpRFGPVAFDTMEKYLNEek-leHIINNEEYII 345
gi 78063218  285 nGSAAASVETNpRFGPLAFKSLEAWFAGkp-vaQKQIMDDALY 326
gi 29827512  317 dGWIDGVIESNpRFGPLAFQTLDSFTKGak-vgQDIVIQDSAY 358
gi 16264669  273 dGKIAAVVECNpRFGPKAFETMLRYAKGek-idPMVINEDKFY 314
gi 121608989 266 sGKMGATVQSSpFFGPIACETARKYARGek-ipGWVKVEDKFY 307
gi 160939590 321 aGEMSATVVSSpMYGPITFDTVEKILAGqe--vPEQTIMEGVV 361
gi 77971103  285 nGSAAASVETNpRFGPLAFKSLEAWFAGkp-vaQKQIMDDALY 326
gi 50952198  234 gGAYNGVIESNpRFGPLAFATLRSFLAGdt-vgQGIVIEDGAY 275
gi 50955716  234 gGAYNGVIESNpRFGPLAFATLRSFLAGdt-vgQGIVIEDGAY 275

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