Conserved Protein Domain Family
PBP1_ABC_sugar_binding_like_2

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cd06310: PBP1_ABC_sugar_binding_like_2 
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Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
Statistics
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PSSM-Id: 107305
View PSSM: cd06310
Aligned: 32 rows
Threshold Bit Score: 281.797
Threshold Setting Gi: 146305721
Created: 11-Jul-2007
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
putative ligand
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                    #                                                                   
3BRS_A        10 CIPKVLdds-sdFWSVLVEGAQMAAkeyEIKLEFMApekeeDYLVQNELIEEAIKr-KPDVILLAaadyektydaakeik 87
gi 108805395  48 RLALIVgvtgdeFYTTMECGARAAArklGARLNVQGpe-efSPAAQTPILNAVVQs-NPDAILIAptdrtamvgpiqsav 125
gi 32474765  143 HFAVIPkgtthiFWQSVKHGAEQAGeeiGAKITFRGpskenDRDEQINVVQGFLNa-RVDGILLApldadalvrpvkeas 221
gi 83649432   40 KLLLVLkgdsnaYWRQVYLGAQKAAdeaGVTLLHRStkddgDIAGQIQILSYHLSqaPPDALILApnsaedltpsvaqyr 119
gi 13472950   30 TIALIPglttdgFYITMRKGAQAAAdalGVNLVFQGap-dfNPVTQVPVLDAVIAk-KPDAILIAptdkvqlveplrkan 107
gi 118470426  61 NIAFLQgvvgdqFYITMQCGAQEEAanlGVTVNTQGpq-kfDPTLQKPILDSIVAs-KPDALLVAptdvqamqmpleqaa 138
gi 134102667  36 NLALLTgmrgepFYVSMECAAKQQAaaaGYNINAQApe-kfEQAEQSQMLTGIIGt-RPGAVIIAptddkalaaplqqak 113
gi 148260369  37 TIALVPgiatdpFYITMQHGAAAEAkklGLHLIWQGgs-sfSPETQIPALQALLAk-HPAALLVAptnekalinpirqfi 114
gi 162451594  42 RIAVVPkgttheFWKSVHAGAVKASrelDVDVVWKGplredDLKAQVDVVSSFVAq-GVSGIVLApldatalrapvraar 120
gi 154508691  67 TIYLVSkgfqhrFWQAVKEGAEQAGeelGYKVNFVGpqdetKVTEQTDQLKSALDs-GPAAIGFAaldskaaadlltein 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                 #                                                               #      
3BRS_A        88 daGIKLIVIDsgmkq----------diadiTVATDNIQAGIRIGAVTKnlv--rksGKIGVISFVKNsktAMDREEGLKI 155
gi 108805395 126 nqDIPVVLVDttieke---------eialaRISSDNVEGGRMAGEALAeqi--ggkGKVLLISVKPGistTDQRKQGFEE 194
gi 32474765  222 raGVPVVIFDsglntd--------pgdfvsYVATDNFEGGKLAGEAMAnalg-ekgGDVILLRYEQGsesTHQREEGFLY 292
gi 83649432  120 arNIPVLVVDsdlag----------dahqgLVATDNYAAGQLAARALLatldlskeRNIALLRLRAGnasTDQREQGFLD 189
gi 13472950  108 daGIPVITVDtfigsgvyqtgagdadfplaYIASDNVLGGEIAARALAtai--gdkGKVYVSNVKPGistTDQREEGFKK 185
gi 118470426 139 aaGIKVVLVDtttndp---------syavsAIASDNEGGGRAAFEAIKqlh--pegGKVMVMGLDPGistTDARTKGFEE 207
gi 134102667 114 nnGVQVVEVDtaledr---------siavaSLSSDNYAGGKLAAQTLAqltg-gkpGAVLALNTKAGtstTDERAKGFEE 183
gi 148260369 115 aaGIPVISVDttisdt---------ailksRITSNNVQGGASAARAIAgfa--hgkGDVAVINVKPGistTDARQKGFLA 183
gi 162451594 121 qaKIPVVVFDsdlas----------ddhvsFVATDNEAAGRLAGEHLGkai--gedGKVVVLRYQEGsasTQHREKGFLD 188
gi 154508691 146 gkGIPVVAFDsgves----------dipvtTVQTDNKAAAAEAAKHMIellk-dkkGSVGMVCHDSTsttGKQRCEGFKE 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                   #    
3BRS_A       156 Glsdd---snkiEAIYYCDSnyDKAYDGTVELLTkyp----disVMVGLNqysATGAARAIKDMsleakVKLVCIDSSme 228
gi 108805395 195 Aikqyp--dieyLGTEYCNDdpTQAASITTSTLQahp----dlaGIFGANvfsGQGAGTGVRQAgkrdqVSVVAFDASpt 268
gi 32474765  293 Siaeys-nirvlSSDQYAGTttESAIDKAQALLNrfgd---eadGICTVCeptAEGALRALRERklagkVKLVTFDSSds 368
gi 83649432  190 Vlrkhd--kiriIAAPYAGDdrGAARSEMLRLLKetp----tidGLFTPNestTIGALVAIRQSgmskqFGFIGFDQTee 263
gi 13472950  186 Emakhs--gitvLETQFNDDdaNKAASQLQAVFArnp----dlvGVFGANlfsALGAANGVKQAgqtgtVKVVAFDAPts 259
gi 118470426 208 Avaedp--gftyVGVQYSHNdpATAAQLIGAQLQrdp----dlvGVFAANlftAEGSATGIKQAgkseqVAVVGFDAGpn 281
gi 134102667 184 Eiakhp--nlrlLPTQYTENepATAAQIVSATLAanp----dlvGVFATNlntGEGAGTALANAgrsgqVQLVGFDASpk 257
gi 148260369 184 Qmkhyk--gmkvVAIEYDDDspTKAFTEAQLLLLkyp----hlkGIFATNvfsGEGVGKAVVAAgkkgkVDVVGYDAEpg 257
gi 162451594 189 Avramp-gvtvaSENQYGGAttESAFHKSESLLLaqraaegaiaGVFTPNestTFGMLQALRKTnvarkVKFVGFDASek 267
gi 154508691 215 YfkanapadlklLDEQIAGEv-TKAADTSLSIIQans----divGMYGSNeaaASGIVQGVAESgk--dVTVVGFDSGkt 287
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
Feature 1                       #                                        
3BRS_A       229 qiqyLEEGIFEAMVVQKpFNIGYLGVEKALkllkk----eyvpKQLDSGCALITKD 280
gi 108805395 269 qvedLRRGNLDVLIAQHpNDIGRRGVQIAVrylesg--eepenKQITTGFTTVTRD 322
gi 32474765  369 lresLSAGEVNAIVLQDpVAMGYQAVKTMAahlrg----etpeQFIDTGVFVATAK 420
gi 83649432  264 leaaMYAGEISNLVVQNpEYMGYLAVQRALdlvrg----kpipAFTDTGVRLLQPL 315
gi 13472950  260 ivdnINTGLVDVAIAQHpAEIGYYGVVSAYahltg----hsipVTIGTGFTIMDKS 311
gi 118470426 282 qiqaLREGTVQALVAQDpGTIGKFGVDEAVtaleg----gensPNVQTGFTIITRE 333
gi 134102667 258 qvedLRNGRVQALIAQDpAAIGREGVDRAIaaikg----qpveRETRTNMIAITKD 309
gi 148260369 258 evklLKQGVISTLIVQRpAEEGRLGVKYAYdiltgksaqvpasKRLANITVTTAEA 313
gi 162451594 268 llgaLREGDIEALVVQNpFNMGYVAVKTMVahlhg----ekvaARIDTGSRVVTRQ 319
gi 154508691 288 qidaIKAGTEAGAVTQSpVKIGYYTVKAAVaalng----aelpKVIDSGFAWYDKT 339

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