Conserved Protein Domain Family
PBP1_ABC_sugar_binding_like_4

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cd06312: PBP1_ABC_sugar_binding_like_4 
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
Statistics
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PSSM-Id: 107307
View PSSM: cd06312
Aligned: 37 rows
Threshold Bit Score: 240.24
Threshold Setting Gi: 15075557
Created: 7-Jan-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                     #                                                                  
gi 52213503   34 KFDYIIhssasntFWQAVKKGMDEACtqvkaQCQMIFTQteg--svSEQASNLQAALAg-KPDAIATTivddkaiep-il 109
gi 148261585  57 KFVFVNhvt-tnpFFVPTQYGIHDACrl--lGCEWQWTGsqt-snvAHMVNAMDAAIAg-KADAIAVPlvdptafnk-pt 130
gi 70607838   86 KIVFINhvt-tnpFFVPTQYGIQDACll--lDCNYQWTGset-sdtTTMVNDMEAAISq-GANGIAVSvispnafdk-pt 159
gi 108803399  60 NFVFVNhvt-tnpFFTPTQYGIEDASal--lGTRYQWTGset-svvREMVDAMNTAISg-GADGIAVSivdpdafnd-pi 133
gi 108804715  69 VIRVSYhnt-slgFANPIREGVEKAKre--lGVDAELIGpan-gsaQEQVSELQTLISqqKVDGLAVSsasndalkp-vi 143
gi 15075557   50 KVVFVAhed--ipFFAPVRAGFKEFGtl-rdWDAQFFARgtp-anvAETVRLQVDALNs-KPDAVGFTrinetafde-ni 123
gi 14022254   42 HIRFFVggaegdaFGTIVYNGAKQAAad--lGPKVDYIFsgw--dvEKMVQQLREAVAv-KPNGIAMMghpgedaimpla 116
gi 50875266   34 KIWFDTggpvggsYNTVVQNGAQQAAtd--lGCEIEFMYsnw--spQKMIENLKKAIAa-GPDGVVVMghpgddayapli 108
gi 90409788    2 SIWFDVggpvggpYATVVQNGATQAAdd--lGVDLRVMYsdw--qpQKMIENFKLALAa-KPTGIVVMghpgdsayenlv 76
gi 16262486   22 SIAFIShssasntFWQAVKKGYDDACek--vGASCQLILtqtegavEQAVANLQAAIAs-RPDAIFVAivdnnaydn-vi 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                     #                                                                  
gi 52213503  110 kearnkGVTVLAANvdsskga------kgsvrqaFIGQGFDAAGYALAQKLAekf-pksGPVNVLVGis--apGQNWSEQ 180
gi 148261585 131 eraleaGIAVFSYNadapags-------gnkrlaYIGQDLFLAGYQMGEKIVkl----vGSGEVALFia--tpGQLNIQP 197
gi 70607838  160 qdalnaGIPVFAYNayiptddpsysqyhnppylgYIGQSLYASGQLFGQRILnl---vpSGSRVALFia--tpGTANIQP 234
gi 108803399 134 rraldqGIPVVAYNangkgpg-------tnpalaYIGQDLFLSGVEMGKRIVel----vEEGPVALFia--tkGQLNIQP 200
gi 108804715 144 aqaynaGIPIISFNtnnpg----------skqmaFVGQDLVQSGRFEAEQLRkel--gdRKGKVVVFsv--dtGAGWSND 209
gi 15075557  124 mrakdaGIPVVLYNvasagy--------ekldvpFVGQDFIPAGRVNGLQAAkyahqltGKTEGRILidnpspGVSALEE 195
gi 14022254  117 eqahkdGIKMMYQNvpvpkvv-------aafgggYVGAQQEQQGRALGAEAFklaglksGDKAIMIGp----fDNESRGA 185
gi 50875266  109 keaeekGIIITSADtelpklma----qyqaagfgYAGVSNYGRGKALASEAInrf-alkKGDRALVWgl---qSRPTRGL 180
gi 90409788   77 neafskGIQVTSVDtalpttma----neqskgfgYVGVSNAARGIHLAKEALrrg-qfkAGDQAMVWgi---kDIAERSD 148
gi 16262486   98 keavdaGILVLAVNvddsega------kgnarkaFIGQGFTAAGYSLAKAQSenf-pkdGPLNLLVGvn--apGQTWSEQ 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        #                                                                               
gi 52213503  181 RGAGVMRFmadykaanpgrkitWKRIDSGTdlAVTAERVGAYLNanp-dtTAYFdtgfwHAGVAKALKDRgvp----pgk 255
gi 148261585 198 RIDGAAAAikklg-----knitYHEIATGPtvNEELSKIRAYYLghqhvkGMFAvdagsTQGVGEVMKQFgla----kkg 268
gi 70607838  235 RIDGIQSVieg--------hytIDVVATGAlvSDEQSAIESYFNshpdvkGMFAvdagsTQGVGNVLREHgiktvsnggt 306
gi 108803399 201 RIDGAIQAiedsg-----apieYEEIETGAelPEELNRIDAYYQghkdvrGMFAvdagsTQGVAQVMKKYnlh----eqg 271
gi 108804715 210 RFSGFEAGmegae-----giqiEGPINSGNepRQAFNAVQNTMTanpdaiAIASldccsVDAAAKWVQQNgkk-----ge 279
gi 15075557  196 RATGTEQGideynkq-ngtnytYETFTTANsqTEALSRIDAKMRatp-dvVGFAstvsgNWFAAIWAEDNgmt-----gk 268
gi 14022254  186 RERGTVAAlkeagv---dvvqiNSVTEWAAdpNLAIPVITAALLnnpgvkAVGYpggqmLGNVPTYMQAAgrk----pgd 258
gi 50875266  181 SSRAIIETlqaagi---evdymEISSEIDKdaSLGTSVIAAYLSsnpdcdIVFTdhgalTAQQENFFRAAglg----pde 253
gi 90409788  149 STRGLISTleeagl---avdflQISPETDKdpSLGTNVITAYLArnpnvkLIMVdhaalTSQMGNFLRNAgir----pqe 221
gi 16262486  169 RAGGVTKFleeykaehsdrevnITRIDSATdlALTADRIGAYLNanp-dtAAYFdtgywHAGVAKVLKDRgie----pgk 243
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
Feature 1              #                   #                                   
gi 52213503  256 ILLGGFDIVpdvlnsmkagYIQVEVDQQpFLQGYLPVIQANlikky--klsaWDVETGKGLL 315
gi 148261585 269 VHGGGFDLLpktldlinsgDLDFTIDQQpYLQGFYTVMEMFmflasgglvgpAEINTGLKFV 330
gi 70607838  307 IAAGGYDLLpatiqnivdgYLDFTIDQQpYLQGFLPTLAIYlylisdtlvypLNIDTGSKFI 368
gi 108803399 272 VRAGGYDLLpktleilregHIDFTIDQQpYLQGFYPVLQLYlykisggltgpAETNTGLKFV 333
gi 108804715 280 IIVVGFDVLpqtadfirngVIQFTISQNpVEQGYQSVKILNdflkk--nkplRDVNTGTKLV 339
gi 15075557  269 FANGGFDLIpgvleaiaaeTSHWAIGQNpFAQGWVTASLLDmqlea--gykpFDYDTGAEVV 328
gi 14022254  259 IFNFGFDTSpqivegfkggWVQLTADQQpFMQGYLPILSLCqqvvl--glapMNVDTGAGFV 318
gi 50875266  254 IIGAGFSLSpataagiksgYVDLVGDGQpYLQGYLPVLQIVltkrf--gfsgLEVQTGGGFI 313
gi 90409788  222 LYVAGFSLSpatadaiktdYVQLVADSQpYLMGYLSVVQVVlskry--gfsgLDINTGAGFV 281
gi 16262486  244 VLLGGFDLVpevlqqmeagYVQVQVDQQpYMQGFIPVMQAYlwkta--gltpSDVDTGQGIV 303

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