Conserved Protein Domain Family
PBP1_ABC_sugar_binding_like_12

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cd06322: PBP1_ABC_sugar_binding_like_12 
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems
This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily, which consist of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
Statistics
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PSSM-Id: 107317
View PSSM: cd06322
Aligned: 7 rows
Threshold Bit Score: 386.032
Threshold Setting Gi: 37520376
Created: 8-Apr-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                    #                                                                   
gi 26249843   30 KIGASLLTqqhpFYIDLANAMKEEAkkdNVNLSVSIanqDLNKQLSDVEDFITkKVDAIIISPVDSKGvqaaiikadkAG 109
gi 83589476   55 VIGVSLLTrehvFYNLIEKAIQEKAqgyKFKPIIMDasqDSNKQLAQVQDFITqKVDAIVLAPTASAGiapavdlakkAG 134
gi 121610351  31 TVGASLLTqqhpFYIELADAMKKQAakdGVRLDLSIanqDLNKQLSDVEDFISkKVDAIILSPVDSKGvkaavlkagaAG 110
gi 37520376   36 VVGVSLLTrqdaFYRELERGLKEEAakqKLTVRLDAgefDLARQQGQLENYTVqKVAAIVVCPTDSQGigpaiaranqAD 115
gi 89209682   30 TIGASLLTqqhpFYVQLKQAMEKAAddnGVELIVSIanqDLNKQISDVEDFIVrGVDAIVLSPVDSKGvvgaiikakrAG 109
gi 16264703   27 GIGASLLTqqhpFYIELAEAMKAEAkekNVALEVAIanqDLNKQLADVEDFIVkGVDVIVISPVDSQGvraaiakaekAG 106
gi 152997120  28 VVCASLLTqshpFYIALGNGLKEGAklqHINLKVSVanqDLAKQINDIEDCITkNVDAIVISPVDSKGirgplkkaerAN 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1              #                                                   #                     
gi 26249843  110 IPVITVDVAaegvpVVSHVATDNYaGGVEAGKLMGkl-lhGKGTVAIISYpaLQSVVARVDGFKKGLsdtpdiKIVAEQP 188
gi 83589476  135 IPVFTIDIKae-gdVKSHVATDNYaGGKLAAKYAAekvlnGKGKVAIITYseVQSCVDREKGFKDALaeypniKVVDVEN 213
gi 121610351 111 IPVITVDIAasgvaVVAHVATDNYaGGVKAGELMAqa-taGKGRIGVLHYptVQSVVDRVEGFKKALsahpqmKIVSIQP 189
gi 37520376  116 IPVFTADIRakegaVVSHIASDNVaGGRLAGEYAAkr-lnGRGQVAIIDQpyIQSVIERVRGFEEALkpypniRVVARLT 194
gi 89209682  110 IPVITVDISaegveVDAHVATDNYyGGRIAGETMAkv-lnGKGQVAIIDYpvVQSVRDRVAGFKEAVskypgiEIVAIQP 188
gi 16264703  107 IKVITVDVPangatVTSHIGTDNFtGGVKAGELMAev-lgNKGKVAIIDYptVQSVVNRVNGFKEAIakhpemEIVATQT 185
gi 152997120 108 IPVITVDIGaenskIVSHIATDNYgGGVVAGKLAVkq-lgGKGQVVMLSYpgISSVEARLQGFRDAVadt-diKIVAVQP 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                              #                     #   
gi 26249843  189 GITr-AEALTTAQNIMQanANLNGLFGFGddaALAAVIAAKSAhn-dnIKIIGFDGMKEArdav-dsekTFAAVIRQYpD 265
gi 83589476  214 CSGsaEKAANLTQDILLkfPDLDLIFAVGdpfAVGAVSTIKAAgr--nVKVIGFDGNPEAiqei-knhgLWVADVVQHpD 290
gi 121610351 190 GITr-AEALTAAQNMLQahPDLAGIFGFGddaALAALASIKAAnklgqVKVVGFDGMAEAraav-dkepAFVGVIRQYpD 267
gi 37520376  195 GDGvrDRSLKAAEDLLQsqRKLDAVFAVNdesAFGVVSAIEAAgr-kgIFVMGYDASEEArkliaggksPLQADIAQDpY 273
gi 89209682  189 GITr-PEALNTAQNILQahPEVDGIFGFGddaALASVVAVKSAgmeddVKVIGFDGMEEArnav-kkeeSFVAVVCQYpG 266
gi 16264703  186 GITr-AEALAAAQNMLQanPDITGIFGFGddaALAAAVAVKAAglesqVKVIGFDGMKEArdav-dgnpVMVGVIQQFpD 263
gi 152997120 186 GKTr-EESMTSTINMLQanPDTDLIFAFGddmMIGAGLAVTKQks--kAVVIGFDGMPEGikav-dendHIIGVVKQDaD 261
                        250       260       270
                 ....*....|....*....|....*....|.
Feature 1                                       
gi 26249843  266 QMGAKAIDAAVdhLNGKPVEKMIPVQPGVYT 296
gi 83589476  291 QIGGKVIDLIAdyFNGKSVPPQVLIPPTIVD 321
gi 121610351 268 QMGARAIGLAVavLAGKKVDKLNPVVPGVYT 298
gi 37520376  274 RIGQETIRAVAthLAGQPVEPVIPVPVRLVD 304
gi 89209682  267 EMGRLGLETALrvIKGEKVEKEIPVLPGLFT 297
gi 16264703  264 QMGKQAIDTAVkvVAGETVPAEQPIVPGVYT 294
gi 152997120 262 AMGKTAMKVVAdyLNGKEVKSEYPIVPVLYT 292

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