Conserved Protein Domain Family
PBP1_ABC_sugar_binding_like_13

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cd06324: PBP1_ABC_sugar_binding_like_13 
Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems
This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.
Statistics
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PSSM-Id: 107319
View PSSM: cd06324
Aligned: 10 rows
Threshold Bit Score: 341.264
Threshold Setting Gi: 15827123
Created: 12-Jun-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic transport protein receptor for D-glucose and D-galactose

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                    #                                                                  
gi 77459332  24 SVLFLNpgstqeaFWVSYSQFMQAAArdlGIDLRILYaqrqpELTLAQARLALQgp--eRPDYLVFVneqy-vapqILRM 100
gi 26989096  23 SVVFLNpglstetFWTSYTRFMQAAAdelGMTLQVQYserraDLTLTQARAILSap--qRPDYLVLVneqy-vapeILRL 99
gi 83643116  46 HVVFFNpqssddtFWSEVIRFARAAAedlNIRLDIFSanhdrLLMRQQIKHILAs---dPPDFIMYKnfkg-napeLLAL 121
gi 71908494  23 SVAFINpgksdeaYWLTATKAMEAAAkdlDIRFEVFYaerqhPRVFELARQIVArpvadRPDYVVITndya-tgpeLLRL 101
gi 71558177  15 SVVFLSpgtetdgYWQSHARVMQTAAdttGMSLKILYtdrdtRKLLAMARDTLQgy--vRPDYLMFSneln-vapeILRM 91
gi 83643783  40 YFLFISpspveniFWGKTGAFAKEVAkdlGVKLEVMYgddqrFSVLKMGMEALQrp--nPPKAIIVGyffs-itekLLQE 116
gi 83649327  24 RFALLIpnd--tpFWNRVALFAQSAAedlNVELHVLDgdadrHLMLRQFERLLKer--rKFDAIIFPnflq-taetFIPQ 98
gi 87122328  23 KVAILYpre--apFWQTFINLMQAAAddlNIELVTFCakgnrFLMKQQLLSVIQgs--nKVDAVVFNnykd-sgsqFIKL 97
gi 27379174  37 NIVFVNpgktgevYWDMVAQTMQAAGrklDAHVEVLTsernyRTMQELGFGVVArp--dKPDFLILSnees-aavpILEA 113
gi 15827123  38 TIGVSYpta-nspFWNAYTRFIDEGShqlGVYINAVSaeedeQKQLSDVETLINq----GIDGLIVTpqstsiaptLLRI 112
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                  #                                                                    
gi 77459332 101 ANGSGVKLFIVNsaltpnqka-----mmadradrIGSLVPNDeeGGYLMMKELIrlhpav---apgesIDLLAFSGlkit 172
gi 26989096 100 SRGTGVKLLLVNngltasqrlsi-egqpdkyaepLGTLMSNDeqAGFQMLHLMLaqlpr-----dagpVDLVAFAGvktt 173
gi 83643116 122 AEEAKVRSFVFNsglnveqerry-ghprerfkqwIGQMLPNDenAGYALANMLFasassrellrggqvLPILAIGGtptd 200
gi 71908494 102 FDAAGIKTFLAYsgisepveravtgqprehfkgwLGSLEPRAqeAGYLTAKALIqqgrraqaqaadgrLHFLAISGdrst 181
gi 71558177  92 STGSGVKLFAVNntltadqiril-gdlpsrypdfIGSLVGNDeqGGYLTAKRLIslahpv---megqeVEMLAFSGtntt 167
gi 83643783 117 ANARDVGVFLVNtsvperdrvlvgqprsekfpnwLGHMYPDDeeVGYLVAAELLrqaqek--wprrksFDLLGISGsmds 194
gi 83649327  99 CEGHPVICVLYNsglegaaaeel-grpkqrfehwIAQLLPDDvgSATAVTVALIrdvrts--ggsggrVNMIAINGfaad 175
gi 87122328  98 ANEAEVFSFLVNsampeakaqem-gaprehypfwLGQMHPDErgANKRIIERLIsdaksh---kpnslINVVGVNGpiss 173
gi 27379174 114 AEVAGVKTLLLSntligedaarl-gpprqtlktwLGDITTDLqtAGARMANALIsaaraekwqspdgkIHILGIGGdeit 192
gi 15827123 113 ATQANIPVVVVDrypgyapg-------qnknadyVAFLGPNNekAGSGIAEALMag----------ggSKFLALGGmpgn 175
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1            #                                                                          
gi 77459332 173 psAQLREKGMQRAlaehp-qvhlRQLVYGGWtqQRAYEQARQLLVryp----kvsLVWAandemAFGAMRAVSEAgkvpg 247
gi 26989096 174 paSQLRVEGMRRAladfp-qvrlRQVVYGGWnrQRAYEQAKQLLEryp----atrLVWSandqmAFGAMQAFEEAghtpg 248
gi 83643116 201 naAIEREMGLHRSlserp-evelQQLVSARWdeELAYKQAVGLLKryp----rtrVIWAandsiAVGSLRGAQSLgykpg 275
gi 71908494 182 paSNRRGEGMRRAvaeag-dvvlEQEIFSGWnrAKAAEQSEWLFQryp----larLVWAgndqmAFGAMQVWEKRggkpg 256
gi 71558177 168 pvSLLREKGMLRAlsehp-evhlRQIALGGWrrDRALEQARVLFKryp----qtrLVWAaneqmAFGAMDALREKggkpg 242
gi 83643783 195 taALDRNAGLKRFlsehtdkvilKQLVYANWfwDEVTARTPKMLEryp----svdLIWAasdlmALAARSVAPEPe---- 266
gi 83649327 176 gpAIAREKGLRAAvglfn-dvtlHQVVYTDWsaEDAESRTEGLLErfp----nvnAIWSanyrtTVGVLAALKKRqrtpg 250
gi 87122328 174 gaAIMRSNALTNTlknienvklkQIVNAESWdeDEASLKFQALMKryr----dihVVWAgsarlVDGILEGEKSLgvkag 249
gi 27379174 193 paSIARNAGLQLAvaaap-dvvvDRMLFANWtqSEAEQVTANYLSwaarkeirpaGIWAgndpmALGALRAATAAglmpg 271
gi 15827123 176 svAQGRKAGLESAltav--ghrlVQFQYAGDseDKGLAAAENMLQahpa--gdanAIWCfndklCQGAIKAVYNAnre-- 249
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1               #                                #                                      
gi 77459332 248 kdVLFSAVNtspealqalvdGRLSALLGGHFtlGGWALVELHD-HAQGVDLNQYGGrdrqipl----lqlidrDHARRiL 322
gi 26989096 249 rdVLFAAVNsspealraridGRLSVLMGGHFtlGGWAMVMLHD-DAHGLALNRDGVrerripv----lqeidqAKARRwL 323
gi 83643116 276 enLLIAGIDwspsaleyikeGKLAGSYGGHFmqGAWSLVLMYD-YHLGRDFADDLGvsihsn-----mglltpDNVDKyL 349
gi 71908494 257 kdAWFSAVNaspeamaalksGRLAALAGGHFicGAWALVMLYD-YDHGRDFAEGEGvevnqsm----ftlfsqKDADRfM 331
gi 71558177 243 edVLFSAINgtslslqaqlnGNLSVVATGHFtlGGWAIILLHR-YDTAQRQARQQVgartidv----lhlvepKDTQRfL 317
gi 83643783 267 --RLIGGVDwsneglqgvkdGRLSHSVGGHFveAGWAVVLLYD-YFNGVDFADYLGvnirth-----lalatsANVDKaI 338
gi 83649327 251 rdVWVNSYDinptslrqvseGALSITAGGHYveGAWSVILAFDhLQGKQRPVATSVfhtpm-------llanhRNAGKiV 323
gi 87122328 250 qdYFTGGVGfkksmleaiesNRVSASAGGHYieGVWVLVLLHD-YFKGIDFVDHGVqtktnm------givtkENVNLyL 322
gi 27379174 272 rnIQVVGLNwsedalreiraGRLLLTDGGHFllGGWSIVLLRD-YADGCDFAATSPrveakt------saitrDNLAAvG 344
gi 15827123 250 keFIFGGMDltpqaiaaienGLYTVSLGAHWleGGFGLAILYR-KIHGQDPAERMVkldllkvdksnvakfkaRYIDNtP 328

                ..
Feature 1         
gi 77459332 323 AM 324
gi 26989096 324 KL 325
gi 83643116 350 QF 351
gi 71908494 332 VR 333
gi 71558177 318 NA 319
gi 83643783 339 DV 340
gi 83649327 324 NV 325
gi 87122328 323 EI 324
gi 27379174 345 DL 346
gi 15827123 329 HY 330

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