Conserved Protein Domain Family
PBP1_ABC_ligand_binding_like_1

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cd06334: PBP1_ABC_ligand_binding_like_1 
Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions
This subgroup includes the type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine-binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 107329
View PSSM: cd06334
Aligned: 34 rows
Threshold Bit Score: 324.592
Threshold Setting Gi: 163744564
Created: 18-Jul-2007
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic Leu/Ile/Val-binding protein with bound valine

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                  ###   
gi 13474354   31 YFPLQSYRVGPyaaGGTGFFGGFIDYLnlinirdGGVNGVKLTWDECETqyevERGVECYERQKShaGAAAWNPLSVGIA 110
gi 83312691   27 LVGHIADITGAtsaVGKPYGQGIADAMnyi-nahGGVAGKKIIFETVDYayevPRAMAAYKKLTGseKATAIQGWGTGDT 105
gi 39937105   28 AIGHLADYSGGtsdVGTPYGQAVADTFawv-nknGGVAGKQLNVDTNDYgyqvPRAIALYKKWSGgdKVAAIMGWGTADT 106
gi 83594835   30 FVGHLKDVTGAtgfVGKLYGEGVNDALvwi-nahGGIDGTRLDFESVDYayevPRAIALYKKWTSqnKMVALQGWGTGDT 108
gi 28901004   28 FVGHLVDFSGPtayVSKHYGSGVRDALlwi-nqnGGINGTELEFETVDMaykvPVAISNYKRWVArkNMVAMQGWGTADT 106
gi 51891845   33 KVGGIFDITGAtgdVGKPHADGARAWFdylnnelGGVNGRKVELVWGDYayqvPKAVELYKKYVNedKVVAILGWGTGDT 112
gi 55980420   31 TLFWSGAITGPtsdAGAPYGAAVEDYCkwa-nerKLVPGVVFNCVVRDDqynnANTQRFFEEAVDrfKIPVFLSYATGAN 109
gi 90417900   28 LVGHLADYTGPtsfVGKQYAPGVADAFkqi-nadGGIDGTLVELDTVDYaykvPEAISLYKRWIGn-GMVALQGWGTADT 105
gi 163722851  31 KVGGIMDTTGAtsdVGKDYAFGMVEAFkyi-nenGGINGNKVKYTWFDYgyriPEAITRYKFLKRm-GVVAIMGWGTGDT 108
gi 62423113   29 PIGVLADLSGAtgdVGSVFNEGMLAYVdnl-nanGGINDRQLEAMSNDYayeiPKAEELYRKYVNd-ESVAIQGWGTGDT 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                         ###                                                            
gi 13474354  111 yamidritaDKVPLITVNHGrtdst-------dgrvfPYVFPLLLNPYSETSGIVNYIAakeggi---dklkgkKIVVLY 180
gi 83312691  106 ealvssvakDEIPYFSASYSghltdpqg--ktsvkgaPYNFFYGPSYSDACRGLVQWAHedwkkk---ggtgkpKFVHMG 180
gi 39937105  107 ealtgflanDKIPDLSGSYAaaltdpeg-tsgkakpaPYNFFYGPSYSDALRAELMWAAedwkak---gksgapKFVHMG 182
gi 83594835  109 ealisfvakDKIPVLSGSYSghltdptgknpktqkpaPYNFFYGPSYSDACRALVQWAEgdwkak---gkegkpKFIHAG 185
gi 28901004  107 ealisfvtkDKVPVFSASYSghltdptgknpktakpaPYNFFYGASYSDACRALVKWAKedwesk---gnttapKFTHIG 183
gi 51891845  113 eamkeliaqDKIPYLSGSFAesltd--------psvtPYNFIVSSTYSQQARVLLDWIKeqk---------pdaKVGIIF 175
gi 55980420  110 lqlkpliqeLRIPTIPASMHielid--------ppnnDYIFLPTTSYSEQVVALLEYIArek---------kgaKVALVV 172
gi 90417900  106 ealitfitrDEIPNISGSYSahltdpqgknpntklpaPFNFFYGPSYSDACRALVQWASedakak----gidnpTFVHTG 181
gi 163722851 109 ealsptvnqDKLPYVSASYSahltd--------paksKYNFFFSSDYSTNARACLTAWFdkkwpqhpdygkrkpRFACCY 180
gi 62423113  107 ealrtrvanDELPFMSGSFAeeltd--------peesPFNFVVAATYSDQARIGMNWISedag--------dktAVAILH 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1             #                                                    #                     
gi 13474354  181 HGSp-YGKETIPIYELLAqkygFTVQQIEVPhpg--neQQSQWLTIRRAkPDFVVLRGWgvmNPVALKTAVKVgypvDHI 257
gi 83312691  181 DNHp-YPNAPKMACGAYAkelgFEVGNEIQYslk-pgdFKAQCLSLKESgAHYAYLGNTsgsTISLLKSCETVgv-tTQF 257
gi 39937105  183 ANHp-YPNAPKAAGEAIAkelgFEVLPPLVFala-pgdYSAQCLSLKSSgANYAYLGNTaasNISVMKACKAAgv-dVQF 259
gi 83594835  186 DNHp-YPNAPKEACADFAtelgFEVLPPVVVslk-pgdFKAQCLTIKQSgANYVYVANLgpsVVSLVKSCKTVgt-dAQY 262
gi 28901004  184 DNHp-FPNAPKDACAEYAkelgFEVQNPVVVslk-pgdFKAQCLSLKESgTNYGYIANLggsVISLVKSCNTVgt-eFQY 260
gi 51891845  176 HDSp-FGQAPVADAKAYAqqigLTWVGEAALpga-aadAVTQVLDLHNKgVEFIMIQNVvkgTAQVLKAVQQQglrdKIQ 253
gi 55980420  173 HPSp-FGRAPVEDARKAArelgLQIVDVQEVgsg-nldNTALLKRFEQAgVEYVVHQNVagpVANILKDAKRLgl-kMRH 249
gi 90417900  182 DNHp-YPNAPKEACAAYAeelgMTVAPPVVVpla-pgdFKAQCLTIKDTgAQYVYMGNLggsVVSLIKSCNTVgv-eATY 258
gi 163722851 181 MSAspYCNAPIKAIRDHAtmlgFEVGADQDVslf-aldAKSQINALKEFkPDVVWHGNTtmsVSATMRDAYSLgl-gADW 258
gi 62423113  171 NDSp-FGTAPVQDAKDWVkekgLDIDVTSYAmpagttnYSGMLSQVDADgADYIMVQNVaspAAQLAKDLADSsg-dQKI 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1           #                                                                            
gi 13474354  258 VGNVWsnsee-dvipaGDAARGYTAITTqasg----ntyPVVQEIVKTVYGAgkgnledksrigsvYHNLGIVNGILNVE 332
gi 83312691  258 LANIWgtdeg-slkatGDAADKLVWVVGastw----sddTPGMKLVREISKVsdasgn---eprpvHYIRAICSVYYMKE 329
gi 39937105  260 MSNVWgmden-aaktaGDAADGVIFPLRtava---wggkAPGMKTVEEISKIsdpsgnvyrpvhyvAAVCSALYMKEAIE 335
gi 83594835  263 MANIWggdse-tqktlGADGDGYVFVAAnafw----gddAPGLALVREIAGSetp--------rthHYIRGVCSTFYMKE 329
gi 28901004  261 MANIWggdkp-vieaaGDGLKDYVFPGMtafw----gddSEGMKLVQQISKLsesepg---efrthHYIRGVCSAFYMKE 332
gi 51891845  254 VVGMTysvdetlltaaGDAAEGFVGTPAfvf------pyDEGPGIDEAVAYAekiglk--redltqKWLQGWVFGRILTE 325
gi 55980420  250 LGAHYtggpd-lialaGDAAEGFLWATSfyma----hedTPGIRLQKEIGRKygrpen---fiesvNYTNGMLVASIAVE 321
gi 90417900  259 MGNPWagdyq-tveaaEAQNLIFPTSTPfyg------adVPGMTLVKTILENgggqvg---drpthHYLRGVCAAYYMKE 328
gi 163722851 259 IINNWgfden-lprlaGPAAEGAIGATPcaffgqkqpdgNYYKNMDKVVEYAakynpgippekrlnRTVQAWADALIFWE 337
gi 62423113  249 VCLNWcgnel-fvtaaGEAAEGHMMVQPvapl---sadkPGHKEIVDYLEANggdpk-----ttanSYVQGWYTMHAMAE 319
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
Feature 1                                                                 
gi 13474354  333 AIRvaqekfghrtltgdevrwgfehlkldpakvealgAKDLFHSi-NVSWDNHEGEG 388
gi 83312691  330 AMEmaaqsgpitgpaik------kamethakdwvpagLEGVCLPs-TWTADDHRGTT 379
gi 39937105  336 WAAknggatgenvak----------gfyqkadwvpagMEGVCNPs-TWTAKDHRGTM 381
gi 83594835  330 AMEwakahggltgesirna--myarkdwvpkglegvcIPSTWTPe-DHRGMTKVFIY 383
gi 28901004  333 AMEwakdnggitgenik-------kgmyvhknwvpkgLEGVCIPa-NWQPEDHRGTT 381
gi 51891845  326 AIRragedvtgetlkaa------fetfneldlggigaPLTFTPTd-HGGMDRARIYQ 375
gi 55980420  322 AIRraqerfkritnetvyqa-ivgmngpnafkpgfavSTKQGVEi-DFTKSEHTGAE 376
gi 90417900  329 AMEwakanggitgkgir-------dgmyqksewvpegLEGVCLPs-TWTPEDHRGLM 377
gi 163722851 338 AANradkagsldget----------iktkgfetmrnfEIGLGSSpvSYTATDHRPTT 384
gi 62423113  320 GIRatldgdneltgani-------realetmgpintgGVFGLGEi-EFSADSHRGSN 368

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