Conserved Protein Domain Family
PBP1_ABC_ligand_binding_like_3

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cd06336: PBP1_ABC_ligand_binding_like_3 
Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions
This group includes the type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine-binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 107331
View PSSM: cd06336
Aligned: 28 rows
Threshold Bit Score: 281.118
Threshold Setting Gi: 56709084
Created: 19-Jul-2007
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic Leu/Ile/Val-binding protein with bound valine

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                     ###
gi 85702840   28 TIGFLAPLSGpvesWGLPGLNGCQIWVDWLNRAGgvlmggrRFPVRLEAYDCgydgAEALTGARHLVQehDAALVMMLGG 107
gi 33595297   32 KLGMSIPLSGsganWGKGSEWLCAKAAEEIKAAGgvkvqgkVYDFECVGYDNkynaAEGAKVAQALVSrdGVKYVAGSIG 111
gi 33599355   32 ILGVSAPMSGaaatWGLGQEWTAKQAAKEINDAGgvkiggtTYKFEVRAYDNkynaAEGTKVAQNIVNrdKSRYVVGSIG 111
gi 115422070  26 KLGVVGGMTGpgapWGLAIDGGVKVAVEEANQAGgldvagkKYKVEVITYDDhykaADAVTAVNRLIDqdDVKFIIGPIG 105
gi 78060710   32 KLGLSVPLSGsgapWGVGADWLCRKAAAEIAASGgvrvkgqTVNFECVTYDNkynaADGAKVAQALVNkdDVKFVAGSIG 111
gi 118045009  32 KFGVSSPMSGaaanWGIGCDWVGQKVVKYINDHGgvraggkTYKVQLTTYDNgytaAGGAQSAQAMISrdGVRYIVQSLG 111
gi 27381482   34 KIGVVGVLSGpaaqWGLALKGAVEFVAAEANRDDlikidgaPCQVSVVAIDSkytaEGGAAAANALAGq-GVKFIIGAIG 112
gi 126464301  26 VVGDLHPITGpanfYGLPESRAIQLAVEEINAAGglsvggeSHTFRIQTEDTqanpTVGVSALKKLVSs-DVRFVIGPLS 104
gi 91780603   35 DIGMISSRSGvyqaFGIPAEDGVRLAVSEINRTGfev-ggqHYKLNLIIRDDrsteVGATTIATEYVRdqNIKFIFGGIG 113
gi 121610756  34 TVGVSDALSGggavYGVPELRAIELAVEEVNAAGgipvggdAYRLKTISYDDkadpTEATNVARKLLDrdGVKVLLGYCC 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                             ###                                                    #   
gi 85702840  108 dsftev-rdylmgQKVLTSSLLTSdlspd---tpyliAPGESLPIYTVTAVEWIAkhrp---dirTVALCAQTDa-LGLP 179
gi 33595297  112 vapvralqslterRGVLLFTAAWGnsikg----pkfpLTFTQMNSVNEISEPMIAhvkklhpeikTVVLLNPNDa-TGQE 186
gi 33599355  112 tapilalqslterNGVILFTSAWGktvkg----pqkpYTLTQSNTPFEILAPLYDyvkakhpaikTVAMLNPNDa-TGKE 186
gi 115422070 106 sasvmamkpiterNKVLLLSNSYSteild----antrYLFRVLPTTYEYNGQLIGwlkknhpelkRVAILSPNDa-TGWS 180
gi 78060710  112 tapvralqslterKGVLLFTTAWGasikgp--sypltFTQMNTTLEIARPLTGFIakth---pikTVALLNPNDa-TGQE 185
gi 118045009 112 tapvqatqslserAGVILLTTAWGksikg----pkfpLTFTNSNTPYEIFEPLFSvvrgqhpnikSVALLNPNDs-TGQQ 186
gi 27381482  113 speltg-lkpiakRNSMLVLASSYakdai---gaqwpLVFHVGPGPSGWADPIIKiakqk-fgmkSVVLVAPNDq-GGTD 186
gi 126464301 105 sgvgpalfpiidrSDGITQIIDGTiaegv----tngrNIFRNQATVSQYDVSVVDlfkak-gygsVTMMTDRFHa-GFVG 178
gi 91780603  114 rlapli-vqitgpEKAIFATASGAaasqfsgkpagryLISTLPPIESRARIVAEAmryyf-pnakSVQRLGPQTa-DNQA 190
gi 121610756 114 sasggavasfmgrEDALMLVGTAGardit---aagnpNVFRTRPPGDYTGAAAGRylyd--kgvrTLGILGVRDvaLFTQ 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                         #                        #     
gi 85702840  180 ALAAYRAAFKAVg-IEIVEEIRYdpgtasAPDVVAPMLAAsPDMLCWCTSytpmVHAMTEFAYLQGYeGQILSCTadcye 258
gi 33595297  187 TEKVAKAAWEKNg-VKVLASDWYergtseFQPIAAKLNSLkPDLVDLASTppadAGLVFRELKALGWnGVKVVEVgtgad 265
gi 33599355  187 TEPVAQKAWEKLg-VKVVSVNWYergttqFQPIAQKLAAVkPDAIDLGVTppadAGVVFRELSVLGWnGVKVQPVgtgaa 265
gi 115422070 181 TQKTQKKAYEDAg-YTVADAKFFersqndFRTLLTSILAKnVDFIELDTVppgpAGIVIRQAREMGFkGRFTKFGgnnva 259
gi 78060710  186 TEKIARKAWEAVg-VKVVSSDWYergsseFQPVAAKLSALkPDGIDLCSTppadAGIVFKELGGLGWnGVKIVEVgtgas 264
gi 118045009 187 AEAQSKQEWAKLg-VKVVSSSFYergtteFQSIATKLANSkTDAVDLGGSapgdAGSVFKELSVQGWnGVKLYPAgtgsd 265
gi 27381482  187 IAPVEAEAYKKN--GIAATEEYYqrgttnFAPLVTRIMNQkPEAVDLASSptgdAGILVKQLRQAGFeGPIGRLGgpgys 264
gi 126464301 179 TQPALAASLKELg-AEIAGEEGYklgdtdFSATLTRVASRnPDVLLIRGYpa-eGALITKQARQLGFeGQVVWEMvspps 256
gi 91780603  191 IFPLLPEPLRAKgfSNIPDPIYYqpdttdFSGILTNLKQSrPDVIFLGQLdparASAIIKQNDDIQAtGGWFAWGldcn- 269
gi 121610756 189 YREALIKRFEQAg-GKVVALETFgghdrdMTPQLTKLKRLdPDAVFISGYve-qAAFAYRQFKEIGMkMPRYGFSggser 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 85702840  259 q-lialtsAEFMEGFLFQFPdfddpalaekafffnqPQAFYEEYNRRFpg-----sWTAVSWEYAAILDIWQSAVEragt 332
gi 33595297  266 g--llatgKDAVDGTYLGAAvavdg-------lsahQKALNDGVKKVTgen--insVQIGFYDSVYAIKAAMEKAQsvdp 334
gi 33599355  266 q--lveigGKAADGVYMGFSgdyega-----qatakQRELNEGMKKAIges--lnpLQLAPYDSVYALKAGMEAANsiep 336
gi 115422070 260 e-tvksagADNAEGTLVYLSadpts------apyarLSAAYGKYHSNSmd-----dFAFYFYDATRLLFKAIQEAGtitn 327
gi 78060710  265 g--liatgGSAVQGVYLGAAvsldga-----satahQRALDDGVRKATgds--inaVQIGIYDAVYALKAAMEKAQstap 335
gi 118045009 266 t--lvkvgGKSVEGVYMGQAadfsga-----tatalQRDLDTQAKQVLhep--lniLQMGVWDGMMALKAGIEKADsidp 336
gi 27381482  265 eisrvaggDPVLKNFYWYEPivv----------dekAQMIAEDYKKMMgadrpennLFFQWVSGVRMVLKAIAKAGtvtd 334
gi 126464301 257 t-vlknisAAEMEGVYNCIPattedyi---algnekAIALEEAYRARFnep--ageLSVLSYDAVHILKAAIEKAGslen 330
gi 91780603  270 -----anaTAGTKTPYVGFPtvgamvd---tpqtpqAREFVEKMKKMTgtlppylyAATYDYDFVFTLVEAMKKSNtvtd 341
gi 121610756 267 q-flkvasSEQMEGVTDLLSvefsvq----algsenAKRFADAYKKKYgee--ptpNTAYAYDQVYVLRDALKSAQstsd 339
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                            
gi 85702840  333 vnsvsvlaamrqlgevnhafgpaqwwGQDMFGLn-HTLIG------DWPVVQ 377
gi 33595297  335 qqvakv----------mpdvkfqsffGEVDFGGk-SVYGS------DQQMQL 369
gi 33599355  337 adivka----------lptivfetsyGKTAFGGa-QTYGS------PQQMLI 371
gi 115422070 328 taavvekiea--spsfegiqgsivwgGKDVYGVn-HQIAT------PAYLGV 370
gi 78060710  336 advakam---------ggvtftsfygSQSGFGGk-AVYGSpqqmllPVIVTQ 377
gi 118045009 337 raiaka----------lptttvetsyGPVGYGGk-STYGT------PQQLLV 371
gi 27381482  335 tekvaealrs--lpvtdpnigtghwiGKEFFGVn-QELSF------PFGVGL 377
gi 126464301 331 eavnaalaeltveevpqlisdyvpgeGGQLFDDr-GQVTL------RSAVSV 375
gi 91780603  342 tdriiga---------lrgltynglvGQITFDAenRAQYG------LDACKI 378
gi 121610756 340 vkkliaalrg--lpvpkevllkyqpiDGKMFDGn-GQAYI------SNGAFQ 382

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