Conserved Protein Domain Family
PBP1_ABC_ligand_binding_like_5

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cd06338: PBP1_ABC_ligand_binding_like_5 
Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions
This subgroup includes the type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however their ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 107333
View PSSM: cd06338
Aligned: 29 rows
Threshold Bit Score: 326.918
Threshold Setting Gi: 116255091
Created: 30-Jan-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic Leu/Ile/Val-binding protein with bound valine

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 154252419  29 RLGAAVSLTGky-ssNGAFTRNGYDLAVkrineeg--gvtvagkRYNLAVIYYDDestpARGAQLVERLIQQdGVKYLLG 105
gi 116255091  34 KIGSSMALSGpl-agGGRQSQLALQMWVedvns------rggllGRKVELVTYDDqgspAQSPGIFSKLIDLdNADLLIA 106
gi 119718662  43 RIGSSLPLTGef-sqPGQAAKQGYEVWQemvnd------aggllGREVELVVKDDasnqNTVVTDYNALISQdKVDLLLG 115
gi 110634840  37 KIGYAISKTGpnaggAGITTLPNYELWVkevneagg-lelpdgsRLPIEVVEYDDrssaEEVVRAIERLATQdEVDFILP 115
gi 84516999   30 RIGAVAPKTGplaggATVTQWPSIYLWVeqvnaag--gltvdgeKMLIELIEYDDqtnpGETIKAVQRLATQdDAHFIIA 107
gi 118054265  36 RIGWAIAKTGvnaggTSVTTAPNYKLWVkeindaggimlkaynkRVPIEVIEYDDrsstEEAVRATERLITQdKVDFVLP 115
gi 84686545   29 IVGAVAPKTGpl-agGAAVTHWPNIKLWvdevnarg-glnvggeQRMLEVIEYDDqtnpAETIKAVQRLATQdNADIILA 106
gi 156742275  67 KVGCSLPLTGaf-adTGIWVERGYRQWAedvna------aggllGRPVELIIYDDesktENAVNLLTRIITVdQVDLLCG 139
gi 94268200   47 QIALSLALSGpy-apMGHSQQRAFRLWQrdina------aggilGRPVELTIVDDqsrpQRAREIYRKFLEEePPDLFFA 119
gi 134101164  25 RIGISLPLTGdf-sePGKGVRRGYEAWAdyvna------rggllGRRVELMILDDqssaDRVAADYEKLINQnGADLVFG 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1         ###                    ###                                                     
gi 154252419 106 PYSSglteaiapvtekYGVPMVEANGAavslf--rkgyrYLFAVLSTTDQYLRGAVELAAsvned-psklRVAMAFENDp 182
gi 116255091 107 PYGTvpaaavmplvkeRGRLLIGQIGYqinsk---vhhdMWFNNSPWNDAESWVGGFFKLgetv---gvkKVAFLAADQe 180
gi 119718662 116 TFSSllnlpasavaekNQMLYVEPAGGspdmfn-rgfkyLFFTQQATSNLQGKVFAEWVAalped-qrpkTAAYPTLDDp 193
gi 110634840 116 PWGTgfnlavaplfdrFGYPQLAVSSVtdkapefvqrwkRSFWMLGGGSDYTDALAGLLKktndegkinnKVAMISVADg 195
gi 84516999  108 PYGTglnlaaaplfdrYGYPQIAVSAItdqqpelaaqfpNMFFTLGTTTALAADVVAVLSdmrdagqmgdKVAMVNVADa 187
gi 118054265 116 PWGTgsnlavgptyekHKYPLLAATSVtdkapdlakrwkHAFFFLGTGGEYAEGLVAMLEkakkdgkinhKIAMINIADg 195
gi 84686545  107 PYSTglniaaapifdrLGFPQITSSAAtdqigelsgqfnDMFFLLGRSTDLAEDAVEVLSdlreageignRVAMVNVADa 186
gi 156742275 140 GYPGtaaaaqmavaekNQMVYVSMGGHmasfs---qgftYVFGAPPLMGQWWYEGLYGWLatlpeaerpkKAAIFTINNp 216
gi 94268200  120 PFSSeitgeimplleeQQYPLLASGAAadelw--eqgyrYLFGIFTPAGKFTFSLLEMLTahg-----veELAVFYTEDp 192
gi 134101164  98 PFSTrlvipaaqvakdYGFLFVEPAGAaeevf--aqgfdNLFYAAPAVAEDHYNHLAAAIlampperrpkTAAYAAMDDp 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        #                                                   #                         # 
gi 154252419 183 FSQDVREGVMEDAakfgMKIVIDDKLppelndMSATLSKAKVLkpdLLLVSGHdkgAALVVRQLADQrv--dVPMVAITh 260
gi 116255091 181 FSQNILAGAKALAgkagFETVYEQTYppttvdFSAMIRAIRAAspdMVFVASYpadSTAIIRAVNEIgvgssVKLFGGGm 260
gi 119718662 194 FAAPNVAGIQEILeaagVETVYQETYaidtknFDTIVNAMKNAdpdLVVHGAQfedGIGLTRSMLKAdf--tPGMFYETn 271
gi 110634840 196 FGIDLVTAARPSFseaeLEVVYDVTYpagttdFTSMINEAAGSgadTFVAFSYppeTFAITQQAQVAkf--nPKVLYLGv 273
gi 84516999  188 FGIELATAARPLFeaagFEIVYETSYplgtqdLSPVIKGAAAAapdAFVAWSYppdTFGLTEQAMIEnl--dVKAFYTAv 265
gi 118054265 196 FGVELANATRKAAkqhgFELVYDKSYpigtqdMTPIINEAKGKgadTFVAYSYppdTMLINEQARTLgl--aPKVLFTGv 273
gi 84686545  187 FGIELMAVAKPAVeaagFELVYETSYplgtqdLSPIMKAVKGAdpdAFVAWSYppdTFGLTEQAMIEel--dVKAFYTAv 264
gi 156742275 217 VGGAILEPMPEKLkalgIEIVVNERYdvpltdAAPLVTKAKAAeadIFFANGFfpdSVQIVKAMRALdy--nPKLIAQGv 294
gi 94268200  193 LSRSAAKGSLRWArwlgLQVELRQQYnpkqadYRELVENARRAgveAVILAGHlheAVVMRQAMVEVgw--qPRVYYATq 270
gi 134101164 176 FAQGTAYGLKEKLeragIRTVVDEVYppnttdFGSIAAKIADSradLVVGGTQyqdAVNLIVTLRQLgy--qPAMAAFSt 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 154252419 261 cdsaq---iaekfGKIAEYTLCAAQWAStlkysdalfgsAADYAALYEETygha-----apyQAAESSAAVQVFADAFER 332
gi 116255091 261 vglqya-svmqalGSQLNGVVNYHTYVPektm---afpgVKEFLDRYAEKakaakvetlgyyVAPFSYASGQILEQAVKA 336
gi 119718662 272 apsfgaqysdgigMENTEGVIYAVSHSPead-----tpgNAEFVAKYKEMfgtd----evpeDAADGYAAAQVMQAAVEA 342
gi 110634840 274 gtgfp--nygadlGPNAEGVMSLGGIDPnn-------qaNTAYRKRHEEVtgra----pdfwGSVVTFASLQMLQEAVKR 340
gi 84516999  266 atpfp--sygarfGAAAEGVLGAGGVNPds-------paFMEYAAAHEAVtgak----pdywASATTYASLEILAQSIEA 332
gi 118054265 274 gtqfp--mfkgkfGAAAEGVMAPGGIDAgn-------pqMQAYLKRFKEVtgqe----sdrfASPIVYTSLQMLQQAIER 340
gi 84686545  265 atafp--afagrfGAAAEGVMGIGGVNTas-------peFMDYAARHEAAtgak----pdywASGMMYASLQILEEAIET 331
gi 156742275 295 gsiip--awvqelGTDGYYVFSGTAVHPslpfe--gisrLNDVAKAKYEApva-------piYFIFGYAWMQALQRGVEG 363
gi 94268200  271 gpgnd--tfveklGEAADGVFGTEQWQYlggva--adrrSEEFVHNYQQQygkl-----pdyFAFTAYSAGLILARAVEE 341
gi 134101164 254 aptnp--efpkaiGAQTEGILSPTGYTPead-----ypsNKEFVAHYTAMhgst-----pteDEANAWTTGQVVAAAVQA 321
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
Feature 1                                                        
gi 154252419 333 AGslepdavrd-----alaetdikTFYGPVKFDEtGKNISkPTVLFQV 375
gi 116255091 337 TGsldnaelak-----ylrtnevqTIVGPIRWGTdGEWSQpRVVMVQF 379
gi 119718662 343 VGniddqeama----swlrenevdTILGSLSWDEtGAPTG-EFLIGQW 385
gi 110634840 341 RGldreavsd------elsngtfeTVLGEVKLED-NQLRK-LWFGGQW 380
gi 84516999  333 VGldraavta------hlkqssfdTILGPISFDE-NNSNAdFWTVGQW 373
gi 118054265 341 VGkidraavtq-----elksgsfeTVLGPVKLEG-QMLTK-LWHVGQW 381
gi 84686545  332 TGtldmaevtq-----fikdnafeTVMGTIDFDDqNSNTA-YWTVGQW 373
gi 156742275 364 AQsldqtaird-----wlksnqmtTVAGTFTFDErGLPPP-YNYLTQV 405
gi 94268200  342 TGglerpaird-----tlagldiqCITGRFRVDErGRQSR-NFTLVTQ 383
gi 134101164 322 VGcadpdlgcqrrlidwlhansvdTVVGKLSWDAtGKPQG-AHLIQQY 368

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