Conserved Protein Domain Family
PBP1_ABC_ligand_binding_like_7

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cd06341: PBP1_ABC_ligand_binding_like_7 
Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions
This subgroup includes the type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine-binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 107336
View PSSM: cd06341
Aligned: 32 rows
Threshold Bit Score: 199.118
Threshold Setting Gi: 111224994
Created: 26-Jul-2007
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic Leu/Ile/Val-binding protein with bound valine

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                    ### 
gi 111224249  15 KIGFITaegg--savSLPEVREGAQAAAayandylGGIGGRPIQLVVCKSqedaASARTCANDMVE--QKVIAVGTGTTg 90
gi 111224994  55 KLMIIAptgt--agtNYPEMVASARAAVrgv-narGGIAGHPVELVHCNErndaASAKKCAQQAVDs-GVLAVVSEVSGt 130
gi 111026386  49 KIGVLAnvtg-tvgkQEGGATRVLEAWArnv-narGGIGGREVELVIKDTradaPTTAAAAEEFIAdeSVVGVFSLTFSt 126
gi 111222939  83 KVGWVStgrt--qavDTSGEIRAAQAVVdyanahlGGLHGHKIELVPCEDksipASAQACGNQFLRe-KVSVVAAGSPGq 159
gi 111222514  68 KIGFVSqd------tFLPSATQGARAAVayvdaelGGVGGRPIELVSCSVnvpeDAARCGAQMANDasLSLVIVGGLSVg 141
gi 111222780  74 VIGTVGqfsg-fagvISKATADAVQAWAqwt-ndrGGLNGHPVKVVVRDDandpAKSLAAVKGMVEndHVIALVGTHESg 151
gi 21222791   58 TVMTWApqdt--gatNKPGMPALARAYArsi-naqGGLAGRKLNVLTCNDhndsVAAAKCARRAVKe-NAVAVVGSYSQy 133
gi 111224420  53 TVGLIVmqsgvaasaQENQWVVGTRAAAayinnklGGFGGRPLKIDLCDSkstsAGALTCANKLAAd-KVDFVSGFALGi 131
gi 111222046  46 KIGSIGsfsg-sqasSEGGSVEVLKAWAqsv-ndgGGIAGHPVDLVIKDLgnnvTGGLAAAKELVQreKVVAIVGEQDNa 123
gi 86739096   81 TVGFVTvens--tvgSYPETRKAAQAAVdyantslGGLDGRPLRLISCATdgspESSQNCANRLVAt-KPLAVVGGIDFg 157
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                           ###                                                 #        
gi 111224249  91 fgdtlvpiiagAKIPYVTGTATagsefa--tdgvfSWTGAFPATLGTMASYAKakg-ykRVALFVTDVp-aAITGANALG 166
gi 111224994 131 ggim--pilqnAGIPSIGSAGIsadgselsspvsyVVSPLTLYPAVCPALLVKag--asHLGLVGYDLs--ASDRLIVMA 204
gi 111026386 127 egsvg-qqiadSDLPVVGGAGFnpkvwg-alpnwyGITTSFPNVTGIQVWAAAeag-atKLSQISCAEd-pSCVASESTF 202
gi 111222939 160 tdpwl-kivapAGIPVALNLVAtqasl---stkdtFIWGNPLGSFGTPAAFARdkk-ltSAAVFVIDVp--AASEPAKQL 232
gi 111222514 142 nkefy-davggRKAILIGNALAsedfv---ttrgvAYTAGSPGVLMGMARFAVeel-kaHTVAGIVPDt-pAGRAAAQQL 215
gi 111222780 152 lesawqkyideKKIPVIGGSATaalwlt--dpnffPTSDTAVNYVVSEVNAAKiag-kkKLGMVVCAEv-pACAQGLTLA 227
gi 21222791  134 adsff-pvlegARIPYIGGYGLtnteft--splsyPVNGGQPALLAGLGSALAgs---cGPVTLVRPDt-iAGDQLSALL 206
gi 111224420 132 ganal-pifakAGIPVHSVPISpqeys---spdsfPYGGGSFSEYPANAAYATakl-gaKKGVLVVSDl-gDSSAVVNSM 205
gi 111222046 124 dttwa-syiasTGVPVIGGLPInipfa----tnadFFPAGTNAFALLYGELALakqvgnKFGFLYCAEa-pQCASSVPLV 197
gi 86739096  158 aeaam-piyetAHIPYVTGSPQlsgelg--shnafAFSGGSLSELLGLTDYLTnir-hvRSVHALYLDlpgLLSAAIQGS 233
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                           #                       #    
gi 111224249 167 KPVFqksGVDLDVISIPrga---adATSQVTSAIAKk------pDALALVGDathCTSVFKAFQAVgatQPKFVIQpcvs 237
gi 111224994 205 EGGAkavSHPINPKIRIpit--tsdFTPAISQLSRSga-----dGAVLVVFDq-aAYAVISKSGQQirtCHAAGTLspky 276
gi 111026386 203 KSAVdevGASYAGLVKVaat--apnYTAECLAIADRg------aDFIQLGLAeaiAPRVAEDCIRQgytGSFGASSnslt 274
gi 111222939 233 IPPFfanAGTKAEVIAIppg--tadMTPQVQTAQKNk------pAMYHVIGDptfCASAIKAIKALgitAPITALDrcig 304
gi 111222514 216 VKPIldaAKVKFRPVFIslqattpdLTTALQASGAGs------aDALITAFPpssCISMYDAIRSLgikPKVITTDqcad 289
gi 111222780 228 GGIAtklGLQFASGLAIsss--spnYTSQCLNMRSAg------vDSIILNSSgevSERFVADCAKQnyrPQLISPGqsfl 299
gi 21222791  207 DSGLasgGHERSHDQRAaed--ataYDDQAERALARdgggpaepGCVVPVLGd-rTGTFMDSFRRArgdRADVRTAtvlg 283
gi 111224420 206 NVFFrraGGSVTAITVPatt---adLSPQVAEAIKAk------pDAIFTALSgvqDATLYEQLEKQgfsPRNIIAQasav 276
gi 111222046 198 KGIAsaiGVQVPVASKVsat--apdYTGVCQQLKDAg------vQSYSVASAsavVIRVSRACSQLglkAEPLSDDgtps 269
gi 86739096  234 QNVLhhkGVSDVKLVPEksd--aadFAPALTQVAAGk------pDAIIVVFQaatCTRIVQAAAALnirSDIYFIGpctt 305
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 111224249 238 ka------vddaaPGALDGSVLFTPsdtd---sddtEAKLYRTVMAKYtpkt-----qtdgYAVTGYQTVLGLAralkgi 303
gi 111224994 277 lat---lgpaadkLVVATAFPELSQaaqfp--evarMVSELDAEQAAGdadaap-alrtttTTTGAWLSVQIAAkvgsqv 350
gi 111026386 275 gt------ltsvpGIQLNGGLNAFPwfm-----espAAQNYRDVMAAQkvsed---dwsstPATAAWASAKLFEktmsgv 340
gi 111222939 305 ad------hgasiPGGFSGVNIIAQanvd---pstpEFKLFDAVLKAYgkgl-----kfdaISMSGYQGMLGLVrgvnsv 370
gi 111222514 290 vpvrahlktvgapGAVPDGWYYANYgynfdlpdvdsGMKTYQYAAAKYakplgsapvelrgFSGPTFGTVMTAAkivnql 369
gi 111222780 300 d--------klldNANYNGAYIANDsfnwf--ggapESADFLQAMKTYksst-----plnaSASAGWAAGVTFGkaaaki 364
gi 21222791  284 svd---qttinasGGASGPYEGAYVtgwyp-avsdpAWDGLKRLIKDQafgdnd-vdpadaGVQTTWIAYTVLKqvvesl 358
gi 111224420 277 dvpn--ffakvspKTAVEGSLYGDIfvsfd-dtaqpDVATYRTAMKTYekdd-----grtvLGQWSFSTIMTNYaigkkq 348
gi 111222046 270 p--------awatEPSLDGARFAEAalpfi-dtttpGGQAYQALLAKYlpklg---nsngpASLYAFAAGRLFEkaarsa 337
gi 86739096  306 pa------vpraaSGRTDNLYFASSylpvgtsdgdaDTAAFRKAIPEAdrss------ssqGSFSAVLNIRSLLagtaqp 373
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                            
gi 111224249 304 sgdvtpasv-tstlkaakniampagHGLTFSCd--gSAIPSLKALCSASSVE 352
gi 111224994 351 sgpltskn----llaqlnrtrhldlGGIVPPLd--lTATTPIPGAERIFNTT 396
gi 111026386 341 vsgttitrd--tvqdaygaikdetlDGLLPQPvtftRGEPSPRIDCAWLYKL 390
gi 111222939 371 pgtdaspaaiatalhtmppttyplgGGATFQCn--gKANSVSPNICSTTGFI 420
gi 111222514 370 gvdkatsf----dvvdralrgfagpAMLQVGPl--kCGQAPFVAVCGHQIGV 415
gi 111222780 365 gpsptsad---iytglyalpakntlGGLIPPTty-tKDKPAVSTPCGWYGVI 412
gi 21222791  359 gdgevssd---tvrralddgpevgtGGLTPGLr--wTFADKLASVGFPRLVN 405
gi 111224420 349 gfatfsgas-likalntetvpvfmsYQYNRAAa--pKGAPAVGNPYVVFVRY 397
gi 111222046 338 atagsdita-sslktalyglkgetlDGLTPPLt--fTQGKAPLVNCYFTMGI 386
gi 86739096  374 tsaall-------talrashdrpnvMAHPFTCd--gKQIDIFPAICNTAVRL 416

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