Conserved Protein Domain Family
PBP1_ABC_ligand_binding_like_9

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cd06344: PBP1_ABC_ligand_binding_like_9 
Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions
This subgroup includes the type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine/isoleucine/valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 107339
View PSSM: cd06344
Aligned: 28 rows
Threshold Bit Score: 213.313
Threshold Setting Gi: 29831346
Created: 11-Jan-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the periplasmic Leu/Ile/Val-binding protein with bound valine

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 86608416   120 SLAVVVPIssn------pnRAKETLRGVAQAQeelfq-qggigGRLLRVVIADDgdnpERATAVAKALVSq-----pEIL 187
gi 54023404   506 SLVYFSGLsytdtnvryphAQVEELAGLAVQQrrall-asdesEPLLRVIVANGgsdmQHATWVVDHQLRgliaddpGVL 584
gi 17232023   457 KIGVAVPIgtn------snVAQEILRGVAQAQqeinh-qggihGKFLKVVLANDdnkpEIAKQVAQRFVQd-----aDIL 524
gi 16331566   131 QIAVVAPVgss------lnIAQEILRGAAQAQeeinq-kggidGRFLHITIVNDandgTLAQQFAGELVKq-----nQIL 198
gi 126660184  187 TIAVAVPIsss------pdSAAEILRGVAKYQtefnq--sstsGQLLEVAIIDSsd-pTTAPNVAQTVINt-----pDIL 252
gi 159030024  192 TIAVVVPIand------pnSAKEILRGVARYQeefn---nsnpGNPLEIVIANDgg-gLQSKAIADDLIQs-----gQVL 256
gi 17232023   885 RIAVSVPIgsn------lnVAKEILQGVAQAQdeinr-qggiqGHLLQVEIATDdnnpEIAQKLASYFVTd-----kQIL 952
gi 22298823   189 TMAAVVPIgts------pdTAKEVLRGVAQYQeqfn---asapHRLLEVVIVNEns-pNGVTSLAEDLINs------SIQ 252
gi 23124354   123 KVAVIASInfd------tnLSEEILRGVAQAQneinn-qggidGKKLQLVIASAen-rEDFAQLDNELFKd-----kSIV 189
gi 119511764  134 QIAVSVPIshk------lyIAEEILRGVAQAQneinqsndrinGKWLQVGIADDkndiPVAKKIAEQAISn-----tNIL 202
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1              ###                     ###                                                
gi 86608416   188 GVIGHNTSdatlaa-aevyqpAGLAMISSTSTstris----------------mlgdAIFRTVPSDQVAGTQLARYALst 250
gi 54023404   585 GVIGLDRSnaetrraigrlgeFGVPVVATTLSadgla----------------easpLYFQAAPSNATQARLIADYVQga 648
gi 17232023   525 AVVGHNSSdasvpa-sdiyqaGKLVMVSPTSSstrltdrp----------rldshgnYIYRTIISFNVIAESLAEYAKta 593
gi 16331566   199 GVVGHNASsatlsa-aptyeaGGLVLVNATSDangit----------------nvgnHIFRVIPQINTSAQTLVQQVGke 261
gi 126660184  253 GIVGYGIDpgsqaa-lqqyesAGVAVLSPLTTsf---------------------qeSTLKTIPIDTKEDELLVNYLQav 310
gi 159030024  257 AVMGHGIDpfsqka-iesyekEGLAILSPLTTnvsq------------------tgnATLKTIPLKDKSQEVLGSYLEav 317
gi 17232023   953 AVIGHNASdasvaa-cpiyqaGKLVNISPTSFsvkls----------------gcgaYIFRTAPNIRLIADILSNYAIkt 1015
gi 22298823   253 GVLGHGTDansraa-lqvyeqAGIAALSPLTTnvipqgngrvq---vqtlplnekgkQLLNTYLDNAAQTLAEAIAKKvp 328
gi 23124354   190 AAVGVRRNaai-------yneKHLVLVFPVERptqaenqekldnnavssqpnssttnYLFHVNPLYDNLVDTHARYIArq 262
gi 119511764  203 AMVGHNASkistev-akiyndNKLVMVTPTSYdldit---------------npqyeYIFKIVPNVNILVNHLRKYYNsq 266
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                          #                                              
gi 86608416   251 l-----------rlqRVAIFYNPNs-------aYSTSLRDAFASTLts--------------egGIVLAEFDLsasdFNP 298
gi 54023404   649 rhpagsaqagqpryrRVSVYHPEAae-----diYVTTLVADLKSELarraidydahtwriqqelNRFPAPCETd--dFDP 721
gi 17232023   594 g------------inRVMICSDSQa--------ADQSFEQAFVNAIiyk------------rlqHINNINCDFasedFRP 641
gi 16331566   262 -------------vdQVAVCYDSKa-------pDGVSFYQEFTTGLlas-------------ggQLAPTVCDLseanFNS 308
gi 126660184  311 gktltqyaaqqqpspNIAIFYNSDs-------gYSQQLQQEIINALpe--------------vqGILIEQIDIsspnFDA 369
gi 159030024  318 aktlanyaskqenspSVVLFYNSDs-------pYSQKLKDSFAKAIke--------------pgGQIVKEIDTtkanFNA 376
gi 17232023  1016 v-----------ktkNLAICVDEQa-------iDNQSFRDEFTSAIiiy-------------ggNLVNIPCDFsapdFNP 1064
gi 22298823   329 -------------naKVALFYNSDs-------pYSNELKNKLTALLpq--------------lgAQVVQPMDVat-gFNA 373
gi 23124354   263 -------------grNVAICGDVRssrdnsgfsSNQILVEQYTQALqky-------------gsKVISTPCNLadkdLDY 316
gi 119511764  267 n------------ykQLFICFDSKe-------qVSTNFKRLFTDIEaq---------------vVSEDDDCNVsknnFQP 312
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                            #                                  #         
gi 86608416   299 QASLQRAVGQga----------------qVAFLAPTas----vAEKALAVARENava----gkpLALLGGDVLFsltt-l 353
gi 54023404   722 GTLLFYAGRNedfptfarsvsrgcltgqaPAILGNDtltrvitDPRATAALPANltvryvakaaPVLLGGARCItgvael 801
gi 17232023   642 ETIVKDAIAQnv----------------dAILLNPQvd----rMSKAVEIGKFNqg-------kVRLLGNPSLQtkti-- 692
gi 16331566   309 QTKMAEIVASga----------------qGLLILPHid----rLDRAFALGDANrg-------rLKLYGNSPLStikt-- 359
gi 126660184  370 NTSVSNLQNNga----------------nVAILALSks----kVSQAVEIATANenq----gspLRLMGGDELYnadi-l 424
gi 159030024  377 KTAIDQAKQAga----------------rVVFLALSkdg--drIDQAVAIAQESs--------gMLLLGGNELYtpdi-l 429
gi 17232023  1065 NQVITEAISSga----------------nGLVLAPHid----rINKALDIAAANkg-------rLRLFASPTLYtsqt-l 1116
gi 22298823   374 NTAMTAARQAaa---------------naVVLAFSRa-----rVNEAVALAIANqtq----tppLQFFGSDQLYgpdl-l 428
gi 23124354   317 RAFVDKAIETena--------------sgFLLLPSVr-----nIYFATKVAQEVkg-------rKPLFASETMYsstt-- 368
gi 119511764  313 NTAISKAQAMqa----------------dSLLLATSvt----tINSFIDLAKASkg-------rLALFSTSTLYtdei-l 364
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                         
gi 86608416   354 qdgGAAVEGLVVAVPWhpqvprNREFAQKAAQLWggq--vswRTALAYDATRVFLQAFsqgatsrnavlar--lqdpnfl 429
gi 54023404   802 gdqPVPIEYEQLCRELpgliedLRRYPELADYHPswa---gdRTGLAFDVSGLFLAAVragrhtdlppnrtaiamqlrer 878
gi 17232023   693 ldaGDVIKGMVIATPWladvspNQEFVQNAKNLWresdlitwRTATAFDATKAIAAALkqeddtrsgiqk----alarnf 768
gi 16331566   360 leqGQSMVDLMVAIPWsskrgaNRPFAEAARKFWggd--vswRTAATYDAVYVVANALavapsreglqkv----ltepef 433
gi 126660184  425 vqgGNAIAGIILAVPWsf--spTDDFAKDALQSWkgr--vswRTATAYDATKALVENVsqnpdra--------------m 486
gi 159030024  430 iqgADSIDGLVLAVPWsf--qaTDPFAKDALKSWrgr--vswRTATAYDTMKVLGEAIakssdra--------------s 491
gi 17232023  1117 qqgQADVNGLMLAVPWhpdgntQNNFSQKAQRLWgns--vtwRSATSYDATLAVIAGLqqsknreelqrv----lrnpkf 1190
gi 22298823   429 ikgDSAINGMILAVPWst--npNDPFAQQAAQAWrgq--iswRTTTAYDATHALAQAMakggdrastqql-----lrqgv 499
gi 23124354   369 lqnGTDLEGMVLPVYWhrdankNNPFAENAFKLWnar--vnqRTAGAYDALQVIITGLkqdntreglqkv----lsnrdf 442
gi 119511764  365 skaKEALKNMVLVTPWhpdafaNNPFPLKAEQMWqrk--vnwRTAMAYDATKVIIEGLkrntnreelpke-----lhkni 437
                         410       420
                  ....*....|....*....|....*....
Feature 1                                      
gi 86608416   430 lqdgasGEVRFLPs--GDRNA--PHVLVR 454
gi 54023404   879 dyqgitGTLGFGAsrvADGSS--IAVLVT 905
gi 17232023   769 slqsatGTIQFLSw--GDRKG--DRVGNA 793
gi 16331566   434 vsstinGEVRFLPn--GDRAG--QATLVQ 458
gi 126660184  487 vfqslnNGVTLSDs-tTDFNLfnEVPLVQ 514
gi 159030024  492 avetlnRGITLQGs-tTDFNIfnQVPLVR 519
gi 17232023  1191 yavgatGKIRFFPs--GDRYL--KNDTIL 1215
gi 22298823   500 qiqgqtASGTFNRv--PLVQA--APGPNG 524
gi 23124354   443 stsgatGMIKFSPs--GERQG--EALLVK 467
gi 119511764  438 picgstGEISFQSg--ERRQP--QAFIIK 462

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