Conserved Protein Domain Family
PBP1_alkylbenzenes_like

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cd06360: PBP1_alkylbenzenes_like 
Type I periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene
This group includes the type I periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Statistics
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PSSM-Id: 107355
View PSSM: cd06360
Aligned: 16 rows
Threshold Bit Score: 388.213
Threshold Setting Gi: 119715096
Created: 30-Jan-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligand
Feature 1:putative ligand binding site [chemical binding site]
Evidence:
  • Comment:based on sequence similarity to the Pseudomonas aeruginosa AmiC complexed with butyramide

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                ###     
gi 85707328   25 KVGLLLPFSGvyaaLGNDIEAGFTTALeqfg-setPATFEIVREDTevkpPVALAKAKKLILqdKVDVISGIVSSgvlga 103
gi 33600577   45 RIGALNSYSKvfaaLGNANLNGMNMYFdqigntiaGRKVEVIREDDeinpQVGLQKLKKLVEsdRCDIVTGIQASnvama 124
gi 72384023   31 RVGLLTIKTGvaagIGQQMQDGFEYLLherggklaGRDVEVVVADTaaspAVAKAKFLQLTErdRVDVVVGPLAAfeana 110
gi 108803046  51 RIGALLTLSGpyatLGESIRNGMETFLrlndnqigGREVQVRYEDSegdpQVALRVYRQLTGqnAVDFLMGPVISteala 130
gi 119715096  47 KIGVLLPYTGpfglYGKPMEAALTARLklddfkvgDRSIELVFEDEatdpATAVSKANKLVDqdGVSAVVCCATGaatla 126
gi 27378498   27 KVGVTATLEGtytvLGEDGMRGHQTALnvlgkkigDKELEFIVASTdatpDSAVRAVRKLIEqdKVQILLSPLSGdegia 106
gi 84502441   26 KIGVISVLEGafagPGMDGVRGAKLAVqeaggavgGNEIEIVTMSSdaspDSAVNAARKLIEqdEVDLIVGPLSGsegla 105
gi 126731081  28 KFGILVATEGafaeGGADGIRNVELAIqqaggtagGLTIETVVAPTdttpDTTVRQARKLIEqdGVDIILGPLSGsegia 107
gi 39933745   35 KVGLLLPYSGtyapLGEAITRGLELYVqsqggklgGRSISFVKVDDesapPKATELTTKLIQseKADVLIGTVHSgvama 114
gi 115522574  39 KIGLMLPYTGtyarLGRFIDAGFRLLIdqrggklgGRDVFFVQLDDeskvESATTNINRLVGreKVDVVIGSVHSgvaia 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                       #  ##                                              #  #          
gi 85707328  104 v--rdmvhgAGVPLIVANAGNDeatgeacspyitRMSFSNGQVNRPMGQWMYdqg-irKVYTLAPDYa-AGRQMIDGFVQ 179
gi 33600577  125 a--veylrqSKAFMLCSGAGVAqlsytg-mpyffRCSISTVPIHATMGEWFYdnv-akEALLTASDFa-GGRNTLEEFKA 199
gi 72384023  111 i--rddiarAKVPVILSSAAAEdltqrkadpwmvRSSSTSAQAMHPFGEYAAttlkyrRIAVVAEDLs-FSHETVAGFQR 187
gi 108803046 131 l--anrlqrDRIILINSNAAANdlsweqksdysyRVSQSNYQLGAAGAEYIFrni-gkTAFTIGMDYv-AGYEVIEAFRI 206
gi 119715096 127 v--gpilaeRGIPQLGPIPNPDglsef---ataaVAAPTAGHDAGKLGTYAAtdldyrSAVIVASDFa-YGHEVAENFKK 200
gi 27378498  107 vk-nfakthPELTFINAASGAQettyvdpapnffRYNMDGAQWQVGLGKYAYddkkyrKIATVGEDYsfIYTQVFGLVLE 185
gi 84502441  106 lr-dlsksyPDVTFLNGSSASQdttlrdasenffRFGGDGAQWMVGVGDYAFndlgyeSVAIVGEDYs-FPYTQVLGFMA 183
gi 126731081 108 mrdyaktipDKTVINGISGALEttwvdp-aenffRFNLDGAQWGAGLGSYVVnekgwtKVATVAADYs-FGYTNFLGFAV 185
gi 39933745  115 m--vkiareDGIPTIVPNAGADiitramcapnvfRTSFANGQIGRATGDAMIkag-lkKAVTVTWKYa-AGEEMVSGFKK 190
gi 115522574 119 m--vkvareSGTLLIIPNAGANeatgllcapnifRTSFSNWQANYPAGKAMAdag-lkTVVTIGWRYt-AGDEMIAAFTE 194
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                            #           
gi 85707328  180 TFtaagGEIVGQEFTpfqktqdFGPYMAQAKSSgaEAVFVFYaggeAISFVKQYDSFglkaeLPLYGSGfltssl---yv 256
gi 33600577  200 GFsrkgGRIIKEIYPplg-nndFSPYLADIRSMspQATFSFYagtdAVRFVKQYDEYglkakSRLTGSGfmldsd---ti 275
gi 72384023  188 TFeeagGKIVQKLWApfn-asdFATLIAQIHPNv-DAVLINFsggnATRFLKQYRDYglkqkIPLLAGMntvdes---ll 262
gi 108803046 207 AYreagGEVVGSAFSapg-tadFATYLTNIRRAepEVVFSFLsgtdAIRFLQQYDSFglkgeIPLIGHDqlaspt---vt 282
gi 119715096 201 GFteagGSIVKEVYAplg-tsdFASYLSQLPDA--DVVFAGFagadAIRFVQQYDKFgvkakMPLIGHGplvtel---vl 274
gi 27378498  186 FCga-gGQVTNRQWVplg-tkdFASVIAALPDDv-DAIYLGLggadAVNFLNQYQQAgg--kAHLMGGSimidqtilssk 260
gi 84502441  184 EYceagGRVPEKFWTpig-nkdYSSIVYSIPQDv-DAIFVVLggadAVNFLTQYAQAgg--dKPIIGSSvtidqsvldsq 259
gi 126731081 186 DFcsagGDIVERFWVplg-ssdFGGVIASLPDDv-DAIYLGVggtdAINFLNQYSQAga--dTNLIGGTimadqtvltsr 261
gi 39933745  191 SFtagkGEVVKDITIafp-dveFQSALAEIASLkpDCVYAFFsgggALKFIKDYAAAnl--gIPLWGPGfltdg----ve 263
gi 115522574 195 AYveqgGRIVEALTLpfp-qtgFEPLIARIAQRkpDAVFAFFagggAVKFVRDYAAAglnktIPLYGPGfltdg----tl 269
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 85707328  257 naeGPAAEGVITALHYVPTLdnpaNAQFVEAFKAKTgr-----vPSEFAVHGYDAGRALIeavkagatdres-----lan 326
gi 33600577  276 paqGRAALGALNSLHYADTLdnpaNLKFVADYRARFkd-----yPSVYSEYGYVAARIIHlaleavdgnsedkd--klra 348
gi 72384023  263 ekmGDEAVGIISAGWYSGAIstpvNERYVEGYRKQYht-----tPGFYATGGYSAGLVLEqalqaggsatlsgr-alada 336
gi 108803046 283 dpaGEAAVGVMACSFYYPNLenetNRRFVEAYRKEYdq-----pPDTIACQGYDTGNIMAkaveeagstepda----lie 353
gi 119715096 275 nqiGPAAVGVGAAFYYSSTLdnaeNERFISTMKAANpd----fvPSHFTAGAWASGSVLLdaieragddatdge--klaa 348
gi 27378498  261 gnaKNALIGTIAASGQADTWedpgWQKFVKAYQDAFppnkrfpsPSLLATNYYGSTMALIlalrevngdlsdnq-skfrt 339
gi 84502441  260 gpfKDLLVGAPSGTPTVSNFegeeWQAFVASYNEAFpdg--fsaPSIFGHHYYMSTKAAMlaleevggdlsdgqeafraa 337
gi 126731081 262 graKEALIGTPTSGPLADDNpdpaWQEYVKAYQDAFpegerfpsPSLFGVGYYVAALAAIeglnevdgdlsdgq-aafkn 340
gi 39933745  264 aaaGPAGDGIKTVLHYVSDLdnaeNQAFVKSFEAAYki-----pPDVFAVQGWDAGQLLDagvkavggdvakrk--elna 336
gi 115522574 270 eaqGEAADGIRTTLHYADDLdhpaNLAFLKAFKAATgk-----dGDIYAVQGYDAAALLDiglravggdtkard--amia 342
                        330       340       350
                 ....*....|....*....|....*....|..
Feature 1                                        
gi 85707328  327 alrqvsfdgPRGALSIDPa-TNNIVQPIYVYE 357
gi 33600577  349 amraikldaPRGPFRFNEe-TQSPIHNVYIRE 379
gi 72384023  337 mhavrlsqsPRGPLTLDRf-GNPVVTVYIRKV 367
gi 108803046 354 vlkgislqsPRGSFTMDPe-THNPIQNYYIGE 384
gi 119715096 349 airstkieaPWGPLAFDPdtGYAIAPTYYYTV 380
gi 27378498  340 alakieldaPNGKIKLDSn-RQAIGTNFVTEV 370
gi 84502441  338 ltdlefvtpTGGTMRLDEn-RNGIVDNFVTEV 368
gi 126731081 341 alstmtletPLGPVHLNEn-RQATGSVFINEV 371
gi 39933745  337 amaaasfasPRGPFKLSAa-HNPVQNFYLREL 367
gi 115522574 343 amaaakidsPRGPLSFNKa-HNPIQNIYLREV 373

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