Conserved Protein Domain Family
GH25_Lys1-like

?
cd06416: GH25_Lys1-like 
Lys-1 is a lysozyme encoded by the Caenorhabditis elegans lys-1 gene. This gene is one of a several lysozyme genes upregulated upon infection by the Gram-negative bacterial pathogen Serratia marcescens. Lys-1 contains a glycosyl hydrolase family 25 (GH25) catalytic domain. This family also includes Lys-5 from Caenorhabditis elegans.
Statistics
?
PSSM-Id: 119378
View PSSM: cd06416
Aligned: 28 rows
Threshold Bit Score: 181.751
Threshold Setting Gi: 67467471
Created: 30-Aug-2005
Updated: 17-Jan-2013
Structure
?
Aligned Rows:
 
active site
Feature 1:active site [active site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1            #                        #                                 # #              
gi 17565328   60 AYAVDISvptt-vsqMNCLKtsRYAAVFIRGFTPFgsg--afDTTSVTSIRNAYSAGLGI-EVYMTPQpls-------sl 128
gi 66800171   21 HIGIDVSsgtn-esgFECFKqkKYSRAIIRCYESIgs----iDTNCKPSIENAKKAGIETiDVYLFPCydc--------g 87
gi 170583503  19 GKAIDITtyvd-rsvFRCLFqaGFTIAFIRVYMSNgng--tvDINSASNIYNAASEGMGT-EIYVEPQprg-------tk 87
gi 17565332   65 AYSVDISfhtt-psdMDCLRdqGYKSVFVRALNPIgnt--yfDRNALNTINNAFEAGLGS-EVYITPNins-------tr 133
gi 118358694 261 IAFYDLLdye--enmYQCLKfyKVSTQLVDGFKDNtt---ifSPQVQGKIDRAQEQGIST-DLLFDPCvntvrq--enfy 332
gi 118373708  21 KLGYDISvwegevncFGCTKqsGYDFVVIEIYSSAkq----fNNYLAQNIKSAYNASLEV-DLYIFPDtt---------r 86
gi 118377284  28 TKLEDVDqfes-idkYICYSnqQFSFQNIVYKQIWg-----yDISHKFGRQYAARTGMKS-NSMYIPCindnpt-kfpfy 99
gi 118377280  26 FFGFTQNqple-eeeFQCLR--DTTYYFIQTITGN-------DPQTVYQARMASFSGLDT-QLIYIPCinkdtd-sypes 93
gi 118377282  25 KYSLAFAydke-vgyTDCLKllGMQQQFIHIYKDYg------TINEGFLQLWINKMPFGA-QLVFEPDvdplge--nkya 94
gi 156063770 111 SLGFDISqlgs-ttfFQCAKk-TKDVVVIRGYEQAcgsggqvDSNFVTSYKNAKAAGFTRiDSYLFPCtgtptgnepqck 188
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                    # #                                         #       
gi 17565328  129 qGYQQLDALYNGlngn---gitIRSVWIQVTs-------pANWqKSATTNVNFLNSIISRAKQY--GLTVGIYTNQYDWS 196
gi 66800171   88 nPENQVTTTSHYlkdy---lkdLDFLWLDIEgp------gQYWsGSYDNNKKFIQGLLDSAKTAg-FKHVGIYTSESQWP 157
gi 170583503  88 sGSEQFMEAYTFltkk---giaVRTIWIKITs-------pINWpNNQTANTDFINKFILCAWKH--GLLVGIYTNWYDWE 155
gi 17565332  134 sGADQISLVYQNllan---ginVRSIWIQVTs-------pTNWvAPMAVRIEFIQDMIRSAKNL--GLSVGIYTSFYDWL 201
gi 118358694 333 tPEHQVTKFSENykf----ltgYENIWFNVIqka---drnCFWsTDANLNCEILTKYISLLQAQt-GKKIGIRSSSLDWS 404
gi 118373708  87 dPAEQINSFFQYliane-tmslFNNVWLDIEn-------eNLFfANCTQNIEFLQAMINTTENYisKDRIGLYASQHYWP 158
gi 118377284 100 tLENQTKNLINFaasyydnrdyGDFFWIVVEann---ikdCQWtNDYQKNCEILTDLVHTASKAsiGLSVGIYSSQEDWI 176
gi 118377280  94 rVTDQVKTFLKTvhq-----vsCQVIWIQISvnd---dekCKWtDDIDFNCQRTKEIANYLKATa-NKNIGFFSSQEDWI 164
gi 118377282  95 tPEVEVGQLVQYnpn----ihgYEYIWINVQqrn----kkNQWsTDVEQNCDLLKRFVSLLKSYs-KNKVAVRSSKIDWV 165
gi 156063770 189 sISTQISEYLQVissn---nmdITMLWLDIEptsastsacNAWnLGAAANEKLAKQWVAAIKAT--GLKWGIYANGNQWS 263
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
Feature 1                             #                                   #            #    
gi 17565328  197 QITGnwatl------ssdvLLWYWHvlgggvtGETPATf-DDFRA--FGSFKKASVKQFAQvesvCSLTVNRDVY 262
gi 66800171  158 GIVGswdg-------gkdyPIWYAN-------YDGAENf-NDFSP--FNGWTKPHMKQYAGnineCGLGIDKNYW 215
gi 170583503 156 QIIAgqitp-----nqrqiRLWYWNllg-sslNDATPPtfADFRP--FGGFNAPMVKQYAKntpiCGICASLNVY 222
gi 17565332  202 EITGgwntf------ssdvFLWYWHvlsmgtdGETTPTl-EDFRP--FGPWRQATVKQFGQveklCGMIVNRNVY 267
gi 118358694 405 NIFGtttnca----nfgnlPLSYIN-------YNQKPNf-QDWQDqqFGSWRGPMMKEFDTte-lCGLTTTLSVY 466
gi 118373708 159 IMCNttvf--------sdlQLWYPR-------WDNQTNf-NDFTP--FGGFANPVMKQFYNdvqiCCTNTDVDWR 215
gi 118377284 177 KLFGdsqqcts--nksyatRVHYKS-------YNSQPNf-DDWAEksFGGWAKPHMKTYQNty-vCGSSIDLSVY 240
gi 118377280 165 KIFGssegcssvsdkknfyPLYYKH-------LDGQPNt-HDYKDhkFGSFENPAMKMYLSte-eCNIKFNANVY 230
gi 118377282 166 NIFGtsesca----eftdlPLRYIH-------LDSNPNf-NDWPQqsFGQWKQPYMKDYSLas-iCEIDTILTVF 227
gi 156063770 264 GMFAsrstd-----vgselPLWAVQ-------DDFEAGv-NTVDTf-MGGWTEAVAKQYYLdttlCGLGVDLDSF 324

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap