Conserved Protein Domain Family
GT8_like_1

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cd06429: GT8_like_1 
GT8_like_1 represents a subfamily of GT8 with unknown function.
A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.
Statistics
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PSSM-Id: 133051
View PSSM: cd06429
Aligned: 11 rows
Threshold Bit Score: 276.192
Threshold Setting Gi: 162683086
Created: 11-Jun-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
putative ligandmetal binding
Feature 1:putative ligand binding site
Evidence:
  • Comment:annotation is based on homology to other subgroups of the superfamily

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1             ### ##                                                                     
gi 50754115   67 ISVVIAASdERLGGAIAAMNSIYRNTr--sNVVFYIVTLndtv---dhlrLWLRNTALKNlryHILNFDPRVLEgkvqvd 141
gi 82179902   65 IPVLITAPeERLGAAVTAMNSIYRNSk--aNVVFNIVTLnesv---vhlsTWLSKTDLKH---KIIVFDPSILLgkiptd 136
gi 152125896  66 IPVVIAASeDRLGGAIAAINSIQHNTr--sNVIFYIVTLnnta---dhlrSWLNSDSLKSiryKIVNFDPKLLEgkvked 140
gi 49522107   65 IAVVIPGVeERLGGLIATINSISSNTk--sNVVFYIITTndtk---khisSWLDGTDLKRvayKLLTFDARVLDgkvrvd 139
gi 162683086 195 VHIFVSTDgADFRPLAVLVNSTISNAvhpeRLHFHLVLPashhsrakhlaAFFQDTKIDIvseNIDFKDMEKHItfrkns 274
gi 162669483 205 FHYALFSD-NILAAAVVVNSTITNAKdp-sKHVFHVVTDklny---gamrMWFLLNPPGAatiQVESVDDFKWLnssycp 279
gi 57899736  217 LHVTIVTD-NVLAAAVAVASAVRSSAep-aRLVFHVVTDkksy---vpmhSWFALHPVSPavvEVKGLHQFDWRdggaia 291
gi 26398609  249 YHYAIFSD-NVIAASVVVNSAVKNAKep-wKHVFHVVTDkmnl---gamqVMFKLKEYKGahvEVKAVEDYTFLnssyvp 323
gi 108862115 296 HHYVIFSK-NVLAVSTTINSTVMNSKds-gSIVFHLFTDsqnf---yamkHWFDRNMYLEatvHVTDIEDHQKLskdvdf 370
gi 147811140 203 YHFCIFSD-NLLAVSVVINSTISNADhp-kQLVFHIVTNginy---gamqAWFLINIEEFswlNASYAPVMKQLldadsr 277
gi 18404824  326 LHFVIISD-NILASSVVINSTVVHARds-kNFVFHVLTDeqny---famkQWFIRNPCKQstvQVLNIEKLELDdsdmkl 400
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                    #              # ###                
gi 50754115  142 p-------------------------------qkadsikPLTFARFYLPNLvphaEKAIYVDDDVIVQDDILELYntplk 190
gi 82179902  137 a-------------------------------qkmetvrPLTFARFYMPAFlpdaEKAIYLDDDVIVQGDIRELFntslk 185
gi 152125896 141 p-------------------------------dqgesmkPLTFARFYLPILvpsaKKAIYMDDDVIVQGDILALYntalk 189
gi 49522107  140 a--------------------------------gaepvkPMTFARFYLPSLlpgaKKVIYLDDDVIVQDDIVQLYntpis 187
gi 162683086 275 k-------------------------------arpelqsVYNFAPFLLPLHfkdvGRFIYLDADIVVKGNIEELIqidlg 323
gi 162669483 280 vlkqlesaamkeyyfkadnantlaagtsnlkyrnpkylsMLNHLRFYLPEVypklDKILFLDDDIVVQKDLTGLWdidlk 359
gi 57899736  292 svmrtieevqrssmeyhqcdasvvreyrrleaskpstfsLLNYLKIHLPEFfpelGRVILLDDDVVVRKDLTGLWeqhlg 371
gi 26398609  324 vlkqlesanlqkfyfe-nklenatkdttnmkfrnpkylsILNHLRFYLPEMypklHRILFLDDDVVVQKDLTGLWeidmd 402
gi 108862115 371 hdmkllrpaeefrv------tfrnhsqsfqkqmkteyisTFGHSHFLLPDLlpslNRVVVLDDDLIVQKDLSSLWnlnmg 444
gi 147811140 278 eyyfkgsed----------------levepkfrnpkyiyLLNHLRFYIPEIypqlEKVVFLDDDVVVQKDLTSLFsldlh 341
gi 18404824  401 slsaefrvsfp------------sgdllasqqnrthylsLFSQSHYLLPKLfdklEKVVILDDDVVVQRDLSPLWdldme 468
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                #                                           ###                         
gi 50754115  191 pgHAAAFSDdcdsttnkvavrgagnqynyigfldykketirklamkantcSFNPGVFVANLTe---WKLQNITKQLEKWM 267
gi 82179902  186 sgHVAAFSEdcdsasskgivrgagnqnsyigyldfkkeaikklgmrantcSFNPGVFVANLTe---WKQQNVTSQLEFWM 262
gi 152125896 190 pgHAAAFSEdcdsastkvvirgagnqynyigyldykkerirklsmkastcSFNPGVFVANLTe---WKRQNITNQLEKWM 266
gi 49522107  188 pgHAAAFSEdcdsvtskfpvrgganqynyigfldykkerirslgikantcSFNPGVFVANLTe---WRRQNITRQLEKWM 264
gi 162683086 324 nrAAAAVEDcsqtfetyfdfnelakiqa----rpekptwvptepikpdacVFNRGVLVIDTNq---WIKQQVTEAILWWM 396
gi 162669483 360 gnVNGAVETcgpsfhrfntylnf-------------snpliarnfksdacGWAYGMNIFDLKq---WKIQDITGIYHKWQ 423
gi 57899736  372 enIIGAVGGhnpgedgvvciektlgdh------lnftdpevsnvlesarcAWSWGVNVVNLDa---WRRTNVTDTYQLWL 442
gi 26398609  403 gkVNGAVETcfgsfhryaqymnf-------------shplikekfnpkacAWAYGMNFFDLDa---WRREKCTEEYHYWQ 466
gi 108862115 445 gkVVGAIQFcevklgqlkay-------------------teernfdnnscVWLSGLNVVELKk---WRDLHITSRYEQLL 502
gi 147811140 342 gnVNGAVETcleafhryykylnf-------------sntiisskfdpqacGWAFGMNANVTAryhfWQGQNADQTLWKMG 408
gi 18404824  469 gkVNGAVKSctvrlgqlrsl--------------------krgnfdtnacLWMSGLNVVDLAr---WRALGVSETYQKYY 525
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                          ##                    ##                                     #
gi 50754115  268 tlnvaeelysrtlagsiTTPPLLIVFYKqHSSIDPLWNVRHLGsnagkry------------------spqfvkaAKLLH 329
gi 82179902  263 ernakedlysktladcmTTPPMLIVFYKhHSNIDPMWNVRHLGatgagnry-----------------saqfvkaAKLLH 325
gi 152125896 267 klnveeglysrtlagsiTTPPLLIVFYQqHSTIDPMWNVRHLGssagkry------------------spqfvkaAKLLH 328
gi 49522107  265 eldvteelyskslsgniAAPPLLIVFYRlYSNINPLWHVRHLGsstgkry------------------spqfvkaAKLLH 326
gi 162683086 397 defqsaes--vlykyglSQPPFLLALYGkYMKLDTPWNVRGLGrnefsererefleskyghkperkpfisldadtAKILH 474
gi 162669483 424 smneer-----tlwklgTLPPGLITFYKlTQPLEKSWHVLGLGynpaie--------------------etdiesAAVIH 478
gi 57899736  443 eknresg---frlwkmgSLPPALIAFDGrVQAVEPRWHLRGLGwhtpdg---------------------eqlqrSAVLH 498
gi 26398609  467 nlnenr-----alwklgTLPPGLITFYStTKPLDKSWHVLGLGynpsis--------------------mdeirnAAVVH 521
gi 108862115 503 qklqkds---vtsfplkVLPISLLVFQDlIYPLEDSWVQSGLGhdygvs--------------------qtdikrSVTLH 559
gi 147811140 409 -----------------ILPAGLLTFYGlTEPLDRRWHVLGLGydlnid--------------------nrlietAAVIH 451
gi 18404824  526 kemssgd----esseaiALQASLLTFQDqVYALDDKWALSGLGydyyin--------------------aqaiknAAILH 581
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
Feature 1         ##  #                                  
gi 50754115  330 WNGhFKPWGRta-----------------syAEVWEKWYV 352
gi 82179902  326 WNGhYKPWGRts-----------------sfSDIWDKWYI 348
gi 152125896 329 WNGhLKPWGRta-----------------syTDVWEKWYI 351
gi 49522107  327 WNGhFKPWGRts-----------------sfPEIWEKWFL 349
gi 162683086 475 FNGkFKPWKQtrpvgpssnvvsrcgskgiecAKLWWEYLS 514
gi 162669483 479 WNGnMKPWLEiai---------------skfKPYWSKYVK 503
gi 57899736  499 FSGpRKPWLEvaf---------------pelRELWLGHLN 523
gi 26398609  522 FNGnMKPWLDiam---------------nqfRPLWTKHVD 546
gi 108862115 560 YNGvMKPWLDlgi---------------hdyKGYWRKYMT 584
gi 147811140 452 FNGnMKPWLKlai---------------gryKPLWERYVN 476
gi 18404824  582 YNGnMKPWLElgi---------------pnyKNYWRRHLS 606

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