Conserved Protein Domain Family
ACCD

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cd06449: ACCD 
Click on image for an interactive view with Cn3D
Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia.
Statistics
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PSSM-Id: 107210
View PSSM: cd06449
Aligned: 9 rows
Threshold Bit Score: 392.94
Threshold Setting Gi: 31615397
Created: 9-Jul-2008
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
catalyticpyridoxal
Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1:catalytic residue [active site]
Evidence:
  • Comment:pyridoxal 5'-phosphate (PLP) forms an internal aldimine bond (Schiff base linkage) with the catalytic residue lysine
  • Structure:1JOA_A; catalytic residue (lys) and cofactor (PLP)
    View structure with Cn3D

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                           #                                            
1J0A_A        22 TPIQYLPNIsrei--gadVYIKRDDLTGlg-iGGNKIRKLEYLLGDALskgaDVVITVGAvhsNHAFVTGLAAkklgLDA 98
gi 8469096    10 TPVQFLKRLseky--gfnIYVKRDDLTElv-gSGNKIRKLEYLLWEALkkgaTTVFTCGGlqsNHARATAYVSrrygLKP 86
gi 28558090   19 TPLEYLPRFsdyl--greIFIKRDDVTPma-mGGNKLRKLEFLAADALregaDTLITAGAiqsNHVRQTAAVAaklgLHC 95
gi 123328402  16 TPIHPLSRLseslggkveLYAKRDDCNSglafGGNKTRKLEYVIPDVLaqgaDTLVSIGGiqsNHTRQVAAIAahlgLKC 95
gi 62286577   15 TPIEKLDRLgkhlggkveIYAKREDCNSglafGGNKLRKLEYVIPDAIasdaDTLVTVGGvqsNHTRMVAAVAakigMKC 94
gi 61211692   16 TPITSMKRLsktlggkveIFAKREDCNSglafGGNKIRKLEYLIPEAIdggyDTLVSIGGiqsNQTRQVAAVAahlgLDC 95
gi 81308375   16 SPITPLKRLsehlggkveLYAKREDCNSglafGGNKTRKLEYLVPEAIdggyDTLVSIGGiqsNQTRQVAAVAahlgMKC 95
gi 61211376   23 SPISYLPNLtavlggkvkLYAKREDCNSglayGGNKVRKLEYLVADAKakgcNTLVSVGGvqsNHTRAVTAVAvasgLKA 102
gi 61211587   16 SPISNLNRLsqhlgskvnVYAKREDCNSglafGGNKLRKLEYIVPDIVegdyTHLVSIGGrqsNQTRMVAALAaklgKKC 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
1J0A_A        99 ILVLRgke----------elkGNYLLDKIMgiETRVYdakdsfeLMKYAEEIAeelkreGRKPYVIPPGga-sPIGTLGY 167
gi 8469096    87 VLFLRkgek---------vlnGNLLLDILLgaEIVEVspeeyerIDEIFDVHKkmrekkGEKVYVIPEGgs-nSLGAFGY 156
gi 28558090   96 VALLEnpigtta---enyltnGNRLLLDLFntQIEMCdal--tdPNAQLEELAtrveaqGFRPYVIPVGgs-nALGALGY 169
gi 123328402  96 VLVQEnwvnysd---avydrvGNIQMSRIMgaDVRLVsegfdigIRPSWEEAMesvrkaGGKPYPIPAGcsehPLGGLGY 172
gi 62286577   95 LLVHEswvphed---vvydrvGNILLSRILgaEVRLVddgfdigIRRSWEKALyevkarGGRPYAIPAGasvhPNGGLGY 171
gi 61211692   96 VLIQEdwvdykd---tmydrvGNIELSRIVnaDVRLDsskfdigIRPSFKNALeeltkkGKKPFPIPAGcsehPYGGLGF 172
gi 81308375   96 VLVQEnwvnysd---alydrvGNIEMSRIMgaDVRLDsagfdigIRPSWEKAMadveesGGKPFPIPAGcsehPYGGLGF 172
gi 61211376  103 VTVQEkwvpidp---plysetGNILLSRLMggDVRLNqetfdirHKKATEDAFkdveakGGKPYYIPAGasdhPLGGLGF 179
gi 61211587   96 VLIQEdwvpipeaekdvynrvGNIELSRIMgaDVRVIedgfdigMRKSFANALqeledaGHKPYPIPAGcsehKYGGLGF 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
1J0A_A       168 VRAVGEIATQSev---kfDSIVVAAGSGGTLAGLSLGLSIlnediRPVGIAVgrfgevmtskldnli----keaaellgv 240
gi 8469096   157 FNAVLEMKDQLnle--sfDAIVCAVGSGGTIAGLSAGISFleyhvPVVGVNVttknsdyfvgkvkrii--sgmeeyglrv 232
gi 28558090  170 VESALEIAQQCega-vniSSVVVASGSAGTHAGLAVGLEHlmpesELIGVTVsrsvadqlpkvvnlqq---aiakelelt 245
gi 123328402 173 VGFAEEVREQEaglgfrfDYIVVCSVTGSTQAGMVVGFAAdgradRVIGIDAsakpeptraqilriarhtaelvglgrdi 252
gi 62286577  172 VGFAEEVRAQEeqlgfafDYMVVCTVTGSTHAGMLVGFAKdgrqrNVIGIDAsatpaktkaqvlsiarhtatlvelgsel 251
gi 61211692  173 VGCVEEIYEQEkqlgfkfDKIVVCTVTGSSFAGIIVGMALtgrqkDVIGIDAsatpektkaqvlriaqntakliglekel 252
gi 81308375  173 VRFADEVRQQEeelgfkfDYIVVCSVTGSTHAGMLVGFAAdgraqRVIGIDAsakpektraqvlriaqntaklvelgrei 252
gi 61211376  180 TNWVVELAKQEkelgvffDVVIVCSVTGSSHAGTVVGAVAegrkrKIIGIDAsgkpeatrnqvlkiarntaallderlei 259
gi 61211587  176 VGFADEVINQEvelgikfDKIVVCCVTGSTTAGILAGMAQygrqdDVIAIDAsftsektkeqtlrian--ntakligveh 253
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                                                
1J0A_A       241 kvevrpELYDYSFGeygkitGEVAQIIRKVGtreGIILDPVYTGKAFYGLVDLarkg--elgeKILFIHTGG 310
gi 8469096   233 netvfeVVDDYRGPgyaipsSEDVEILKEVAsieGIILDPVYTAKAFRGMIEMfrn----sekNVLFIHTGG 300
gi 28558090  246 asveilLWDDYFAPgygvpnDEGMEAVKLLArleGILLDPVYTGKAMAGLIDGisqkrfkdegPILFIHTGG 317
gi 123328402 253 teadvvLDTRYGGPeyglpsAGTLEAIRLSArleGMMTDPVYEGKSMQGMIDMvrrgefpqgsKVLFAHLGG 324
gi 62286577  252 aeddvvLLEDYAHPrygipsEETKEAIRLCArleGMITDPVYEGKSMQGMIDLvqkgffpagsRILYAHLGG 323
gi 61211692  253 tesdvnIDTRFAHPaygipnEGTIEAIKLCGateGVLTDPVYEGKSMQGLIHLvrnneiaegsKVLYIHLGG 324
gi 81308375  253 taedvvLDTRYAYPeyglpnDGTLEAIRLCArleGVLTDPVYEGKSMHGMIDMvrngefpegsKVLYAHLGG 324
gi 61211376  260 keedviLDDRFHAGiygipdDETIAAMKLAAqtdAFITDPVYEGKSMAGMIRLvkegaikegsNVLYIHLGG 331
gi 61211587  254 efkdftLDTRFAYPcygvpnEGTIEAIRTCAeqeGVLTDPVYEGKSMQGLIALikedyfkpgaNVLYVHLGG 325

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