Conserved Protein Domain Family
p23_NUDCD1_like

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cd06493: p23_NUDCD1_like 
p23_NUDCD1: p23-like NUD (nuclear distribution) C-like domain found in human NUD (nuclear distribution) C domain-containing protein 1, NUDCD1 (also known as CML66), and similar proteins. NUDCD1/CML66 is a broadly immunogenic tumor associated antigen, which is highly expressed in a variety of solid tumors and in leukemias. In normal tissues high expression of NUDCD1/CML66 is limited to testis and heart.
Statistics
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PSSM-Id: 107242
View PSSM: cd06493
Aligned: 5 rows
Threshold Bit Score: 158.842
Threshold Setting Gi: 66472492
Created: 29-Jun-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74732699  278 YYWQQTedDLTVTIRLPEdstkeDIQIQFLpdHINIVLK-DHQFLEGKLYSSIDHESSTWIIKesNSLEISLIKkneglt 356
gi 149410565 180 YHWQQTedDLTVIIHLPQdtskeDILVQFSpdHLSVALKnQPSLVEGKLYSSIDHESSTWIIKenNSLEVSLIKkdegpt 259
gi 66472492  281 YFWQQTeeDVTLCVRLPEgttkdDIRFKLTvdCLRVRVGdYAPLLDGQLFAPVDPEASTWTMNddKSLEVSLQKrsegpl 360
gi 148229636 280 YNWQQTgeEVTLTFLLPEgktkeDLNIKFLpgEIDISIKdQGTFLKGQLYSDVDCESSAWIMKegRGVEVTLTKrepgct 359
gi 126322217 279 YYWQQTeeDLTMIIHFSEdvskeDIEIRFSpdHISIALK-KQPYLEGKLFSSIDHESSTWIIKenKSLEVSLIKkdeglt 357

                 ....*
gi 74732699  357 WPELV 361
gi 149410565 260 WPELI 264
gi 66472492  361 WSEVV 365
gi 148229636 360 WAELV 364
gi 126322217 358 WPELI 362
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