Conserved Protein Domain Family
Glyco_transf_WecG_TagA

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cd06533: Glyco_transf_WecG_TagA 
The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common antigen (eca) synthesis. B. subtilis TagA plays a key role in the Wall Teichoic Acid (WTA) biosynthetic pathway, catalyzing the transfer of N-acetylmannosamine to the C4 hydroxyl of a membrane-anchored N-acetylglucosaminyl diphospholipid to make ManNAc-beta-(1,4)-GlcNAc-pp-undecaprenyl. This is the first committed step in this pathway. Also included in this group is Xanthomonas campestris pv. campestris GumM, a glycosyltransferase participating in the biosynthesis of the exopolysaccharide xanthan.
Statistics
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PSSM-Id: 119439
View PSSM: cd06533
Aligned: 224 rows
Threshold Bit Score: 99.0807
Threshold Setting Gi: 84685615
Created: 8-Jan-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 135271     57 LSSSNFILPDGIGVVMMSRLTNnr----lQSRIAGYDVFKELLGVAnkkkkRIFLYGAKKDVikgvvskissEYPNIKIA 132
gi 84685615   53 TSGDDHVVIDGGTTARIVSKLTgvp--ceSLSFDYAGVACAAMDRLaqrgaRLGLIGGTSDEvsrvatflrdRHPGLRVV 130
gi 159185180  71 LRQADQIHADGMSLVIFSRKFCrq---alRERVATTDLVHAVAKRAeetgsRFYFLGGSEEVnraaveemqrLYPRLVFS 147
gi 39937641  116 LMEADAIHADGMPLVFVSRFRCgq---slPERVATTDLFHEVAREAskrgaTMYMLGANEESnrravermqrRYPGLRLV 192
gi 89067921   71 LAAADIVHADGGFLVTLSRHRAgp---aiPERSATTDMIHDFARAFsdgtgSFYLLGGPEEInaacarelrrRYPGLAIA 147
gi 83647372   64 MNNVDLVHADGQSVVTLSRWFSer---piAERSATTDMIHDIPVHYap-tlKHFFLGGLKDVveqaakiysdTYANAEIV 139
gi 75342194   76 FRGADLINADGQPLVADSKLQSwf---plPERVATTDLFHVVARKAeavgrTFYMFGASEAEnaaavenvrtMYPNLKIV 152
gi 186459490  56 TSKYDYFIPDGMPLIWCLNRAGag----lKDRVYGPTFMREFLSKVpk-qyTHYLLGGSEECgsrikeifqkLNPGIQFV 130
gi 114562553  67 LLQADLIHADGQSVVTFSKWVKgr---niPERTATTDMIHDIPNYFes-niNHFLLGCENDIvenacklmskRYKNFKIS 142
gi 116671162  60 YEDSDVVLLDGAPVLWLWGRSGeadgpvmDYRLGSTDWIPALGSVEgl--eRIAVIGAGAEAnaravarlagIVPNAKVA 137
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 135271    133 gy----sDGYVQDRtlv--------akQIARANPDMVFVALGyPHQEKFIHNyrhlf-pkavsIGLGGsFDVFSGNVKRa 199
gi 84685615  131 laa-sgyHPSHRQLm-----------sDVAVARPDVLLVSMGsPRQEALALAlkarldhptaiVTCGA-FVHQTARHPYy 197
gi 159185180 148 gr----rNGYFSRAeeda------vlaDITTSKTDILWVGFGiPLEQRFVSRnldrlsgiaviKTCGGlFDFLAGRNSRa 217
gi 39937641  193 gh----rHGYFANEaeei-----avcrEIGALAPDILWVSMGvPREQAFVVRnrhrlttvgviKTSGGlFDFLSGSKPRa 263
gi 89067921  148 gr----rHGFFGHEdehg------iidHINRSGADIVWIGLGkPREQAIARRwrdrl-tarwvITCGGcFNYVTGHYRRa 216
gi 83647372  140 gv----rDGYFSAAdeln------iveEINQSGADVLWVGLGkPKEQEFCIRhkdkl-kvpvvISCGGcYNFLTGHYKRa 208
gi 75342194  153 gh----sHGYLRGEslra------kveEINALAPDYLWVALGvPNEQAFVEQytplltnvgviKTSGGlFNFLSDSRSRa 222
gi 186459490 131 ga----fHGRCGLDgildgnseqmvmaDLARLSPDFIWVGFGtPKQQAWTRKhkqli-rrgviLTVGFaFDVNAGMKPDa 205
gi 114562553 143 gf----nDGFFSIEeede------iidKINSSRVDVLWVGLGkPKEQEFCIRnkekl-nvsviITCGGcYNYITNDYPRa 211
gi 116671162 138 gmpgegwNSALEGEav----------aWLQELRPQMVLLGLGmPLQEMVLRRrlsvl-ppavyCAVGGaIEQIAGIQKLa 206
                        170       180
                 ....*....|....*....|....*.
gi 135271    200 PSWMirlNLEWFYRLILNPWR-WKRM 224
gi 84685615  198 PEVYtrrNLRWLYRALNTPHI-APRI 222
gi 159185180 218 PQWMqdmGLEWLYRAMLEPKRlGKRY 243
gi 39937641  264 PQWMqkvGLEWLWRMALEPRRlGVRY 289
gi 89067921  217 PGWMqraNLEWLHRLCTDPRRlARRY 242
gi 83647372  209 PEWVqnnGLEWVHRMVLNPRKlFWRY 234
gi 75342194  223 PQWMqkfGLEWAWRTWLEPRRlFWRY 248
gi 186459490 206 PIWMqrlGLTWVFRLLSEPKRlASRY 231
gi 114562553 212 PVWMqkiGFEWLHRMSTNPRKlFYRY 237
gi 116671162 207 PRWLgrlGLEWAWRLMLHPRRvAYRV 232
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